T10767 |
Cerivastatin sodium
|
143201-11-0
|
98%
|
|
Cerivastatin sodium is a synthetic lipid-lowering agent and a highly potent and orally active HMG-CoA reductase inhibitor (Ki: 1.3 nM). It also inhibits the prol...
|
T10070 |
2'-Ethyl Simvastatin
|
79902-42-4
|
98%
|
|
2'-Ethyl Simvastatin is a Mevinolin analog with HMG-CoA reductase inhibition.
|
T11572 |
HMG499
|
2416941-68-7
|
98%
|
|
HMG499 is a potent and selective HMG-CoA reductase inhibitor with an IC 50 of 0.41 μM. HMG499 can eliminate statins-induced accumulation of HMGCR, lower serum ch...
|
T6994 |
SR12813
|
126411-39-0
|
99.95%
|
|
SR12813 (GW 485801) is a pregnane X receptor (PXR) agonist.
|
T0687 |
Simvastatin
|
79902-63-9
|
99.95%
|
|
Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cho...
|
T3116 |
Atorvastatin hemicalcium salt
|
134523-03-8
|
99.89%
|
|
Atorvastatin hemicalcium salt (Atorvastatin Calcium), an effective HMG-CoA reductase inhibitor (IC50 = 8 nM), is utilized as a cholesterol-lowering medication.
|
T6450 |
Clinofibrate
|
30299-08-2
|
99.84%
|
|
Clinofibrate (Lipoclin)(IC50 of 0.47 mM), a lipid-lowering agent, inhibits hydroxymethylglutaryl coenzyme A reductase (HMGCR). It is utilized to control high cho...
|
T1676 |
Rosuvastatin
|
287714-41-4
|
99.8%
|
|
Rosuvastatin (ZD 4522) is an antilipemic agent that competitively inhibits hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the...
|
T20887 |
Atorvastatin Sodium
|
134523-01-6
|
99.79%
|
|
Atorvastatin Sodium (Lipitor) is a competitive inhibitor of HMG-CoA reductase and increases the expression of low density lipoprotein (LDL) receptors on hepatocy...
|
TN1438 |
Beta-Amyrin acetate
|
1616-93-9
|
99.74%
|
|
beta-Amyrin acetate inhibits HMG-CoA Reductase (HMGCR) and sEH activity with IC50 of 3.4 μM. beta-Amyrin acetate has anti-inflammatory, antifungal, antioxidant, ...
|
T1664 |
Meglutol
|
503-49-1
|
99.73%
|
|
Meglutol (3-Hydroxy-3-methylglutaric acid) is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by...
|
T2534 |
Pitavastatin calcium
|
147526-32-7
|
99.71%
|
|
Pitavastatin calcium (NK-104) is a potent inhibitor of HMG-CoA reductase (Ki: 1.7 nM). It lowers both total cholesterol and low-density lipoprotein cholesterol i...
|
T20765 |
Atorvastatin
|
134523-00-5
|
99.69%
|
|
Atorvastatin is an orally active HMG-CoA reductase inhibitor that has the ability to effectively lower blood lipids by activating liver cytochrome p450 to accele...
|
T24865 |
Tenivastatin
|
121009-77-6
|
99.68%
|
|
Tenivastatin (Simvastatin acid) is an anti-hyperlipidemic HMG-CoA reductase inhibitor that inhibits the production of reactive oxygen species (ROS) and can be us...
|
T10324 |
Anhydrosimvastatin
|
210980-68-0
|
99.63%
|
|
Anhydrosimvastatin (Dehydro simvastatin) is an impurity of Simvastatin. Simvastatin is an HMG-CoA reductase inhibitor.
|
T3698 |
Alpha-Asarone
|
2883-98-9
|
99.59%
|
|
alpha-Asarone (trans-Asarone) is a psychoactive compound with antidepressant-like activity in mice.
|
T1207 |
Lovastatin
|
75330-75-5
|
99.59%
|
|
Lovastatin (MK-803) is an HMG-CoA Reductase Inhibitor, used for lowering cholesterol.
|
T13131 |
Tert-Buthyl Pitavastatin
|
586966-54-3
|
99.57%
|
|
tert-Buthyl Pitavastatin is Pitavastatin metabolite. Pitavastatin is a potent inhibitor of HMG-CoA reductase.
|
T1487 |
Fluvastatin sodium
|
93957-55-2
|
99.46%
|
|
Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol lower...
|
T0672 |
Pravastatin sodium
|
81131-70-6
|
99.08%
|
|
Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.
|