T68156 |
(Rac)-Telinavir
|
162679-88-1
|
100%
|
|
(Rac)-Telinavir shows anti-HIV activity.
|
T2942 |
Psoralen
|
66-97-7
|
100%
|
|
Psoralen (Ficusin) is a furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.
|
T0282 |
Q-VD-OPH
|
1135695-98-5
|
100%
|
|
Q-VD-OPH (Quinoline-Val-Asp-Difluorophenoxymethylketone) is a pan-caspase inhibitor with potent antiapoptotic properties.
|
T1776 |
Plerixafor
|
110078-46-1
|
100%
|
|
Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.
|
T28255 |
Opaviraline
|
178040-94-3
|
100%
|
|
Opaviraline (GW-420867X) is a potent reverse transcriptase inhibitor that inhibits Human immunodeficiency virus 1 and has the potential to treat HIV infection.
|
TJS1779 |
Protosappanin A
|
102036-28-2
|
100%
|
|
Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inf...
|
T2279 |
Tizoxanide
|
173903-47-4
|
100%
|
|
Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine. Lamivudine (2', 3'-dideoxy-3'-thiacytidine, commonly called 3TC) is a potent nucleoside analog...
|
T7624 |
DAPTA
|
106362-34-9
|
100%
|
|
DAPTA (Adaptavir) is an inhibitor of CCR5, shows potent anti-HIV activities.
|
T7903 |
Saquinavir
|
127779-20-8
|
100%
|
|
Saquinavir (Ro 31-8959) is a potent HIV protease inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS.
|
T1525 |
Ritonavir
|
155213-67-5
|
100%
|
|
Ritonavir (ABT 538) is a peptidomimetic agent that inhibits both HIV-1 and HIV-2 proteases. Ritonavir is highly inhibited by serum proteins but boosts the effect...
|
T5863 |
Indinavir sulfate
|
157810-81-6
|
100%
|
|
Indinavir sulfate (L735524 sulfate) is a HIV protease inhibitor.It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM.
|
T6016 |
Maraviroc
|
376348-65-1
|
100%
|
|
Maraviroc (Selzentry) is a C-C Chemokine Receptor Type 5 (CCR5) antagonist, and for MIP-1α(IC50=3.3 nM), MIP-1β (IC50=7.2 nM) and RANTES(IC50=5.2 nM).Maraviroc i...
|
T6065 |
Triciribine
|
35943-35-2
|
100%
|
|
Triciribine (NSC-154020) is a DNA synthesis inhibitor, and it also inhibits Akt and HIV-1/2.
|
T24362 |
L 756423
|
216863-66-0
|
100%
|
|
L 756423 (L756423) is a novel potent and selective and competitive HIV protease inhibitor with a Ki value of 0.049 nM for HIV-1 PR.L 756423 blocks the spread of ...
|
TN1103 |
Diphyllin
|
22055-22-7
|
|
|
Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.
|
T7700 |
Lersivirine
|
473921-12-9
|
|
|
Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.
|
TQ0217 |
Gomisin G
|
62956-48-3
|
|
|
Gomisin G is a natural compound and exhibits potent anti-HIV activity (EC50: 0.006 μg/mL; therapeutic index: 300). It is a good substrate of CYP2C9.
|
T13647 |
Dextran sulfate sodium salt (MW 4500-5500)
|
9011-18-1
|
|
|
Dextran sulfate sodium salt (MW 4500-5500) is an anhydrous glucose polymer with a molecular weight range of 4500-5500. Dextran sulfate sodium salt (MW 4500-5500)...
|
T16764 |
RN-18
|
431980-38-0
|
|
|
RN-18 is an inhibitor of HIV-1 viral infectivity factor (IC50: 6 μM in nonpermissive H9 cells).
|
T9212 |
IMB-301
|
64009-84-3
|
|
|
IMB-301 is a small molecular inhibitor via virtual screening according to the hA3G model.
|