T3435 |
Vicriviroc maleate
|
599179-03-0
|
97.51%
|
|
Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus. The IC50...
|
T61793 |
HIV-IN-6
|
301357-74-4
|
97.12%
|
|
HIV-IN-6 is an HIV viral inhibitor that inhibits the replication of the HIV virus.HIV-IN-6 has anti-HIV viral activity and works by targeting Src family kinases ...
|
T8233 |
BRD3308
|
1550053-02-5
|
97.12%
|
|
BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK.
|
T68103L |
Mk-6186 HCl
|
|
97.09%
|
|
MK-6186 HCl, a novel non-nucleoside reverse transcriptase inhibitor with antiviral activity, can be used to study HIV.
|
T6007 |
Birinapant
|
1260251-31-7
|
97.08%
|
|
Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IA...
|
T16098 |
Islatravir
|
865363-93-5
|
97.03%
|
|
Islatravir (MK-8591) is an effective anti-HIV-1 agent. It acts as a nucleoside reverse transcriptase inhibitor (EC50s: 0.068 nM, 3.1 nM, and 0.15 nM for HIV-1 (W...
|
TN2097 |
Pomolic acid
|
13849-91-7
|
96.84%
|
|
Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-mediat...
|
T30479 |
Bis-T-23
|
171674-76-3
|
96.81%
|
|
Bis-T-23 is a promoter of actin-dependent dynamin oligomerization, an HIV-I integrase inhibitor, and a Telstar derivative. Bis-T-23 promotes actin-dependent dyna...
|
TN1727 |
Helichrysetin
|
62014-87-3
|
96.32%
|
|
Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selecte...
|
T6256 |
YYA-021
|
144217-65-2
|
95.82%
|
|
YYA-021 inhibits HIV entry, with high anti-HIV activity and low cytotoxicity.
|
T6001 |
Nelfinavir Mesylate
|
159989-65-8
|
95.81%
|
|
Nelfinavir Mesylate (Viracept) is an effective HIV protease inhibitor (Ki: 2 nM).
|
T4182 |
Lavendustin B
|
125697-91-8
|
95.72%
|
|
Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived gro...
|
T3321 |
Oleanonic acid
|
17990-42-0
|
95.58%
|
|
Oleanonic acid (3-Ketooleanolic Acid) is relatively non-toxic, hepatoprotective, and exhibits antitumor and andantiviral properties.
|
T1131 |
Ivermectin
|
70288-86-7
|
95.35%
|
|
Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.
|
T29037 |
UC-781
|
178870-32-1
|
92.17%
|
|
UC-781 (NSC-675186) is a potent and selective inhibitor of human immunodeficiency virus HIV-1 non-nucleoside reverse transcriptase (NNRTI) I with a C50 value of ...
|
T11465 |
Lenacapavir
|
2189684-44-2
|
100.00%
|
|
Lenacapavir (GS-6207) is a potent capsid-targeting inhibitor of HIV replication. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells.
|
T8311 |
Obefazimod
|
1258453-75-6
|
100%
|
|
Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) (IC50 : 0.1 μM - 0.5 ...
|
T67798 |
(2RS)-FPMPA
|
135295-27-1
|
100%
|
|
(2RS)-FPMPA(FPMPA) has antiviral activity with an IC50 value of 1.85 μM measured in human MT12 cells infected with SHIV (DH4R).
|
T2942 |
Psoralen
|
66-97-7
|
100%
|
|
Psoralen (Ficusin) is a furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.
|
T0282 |
Q-VD-OPH
|
1135695-98-5
|
100%
|
|
Q-VD-OPH (Quinoline-Val-Asp-Difluorophenoxymethylketone) is a pan-caspase inhibitor with potent antiapoptotic properties.
|