T16729 |
Remetinostat
|
946150-57-8
|
98.67%
|
|
Remetinostat (SHP-141), a hydroxamic acid-based inhibitor of histone deacetylase enzymes, is currently being developed for the treatment of cutaneous T-cell lymp...
|
T3983 |
TMP195
|
1314891-22-9
|
98.66%
|
|
TMP195 (TFMO 2) is a selective class IIa histone deacetylase (HDAC) inhibitor.
|
T6678 |
Splitomicin
|
5690-03-9
|
98.64%
|
|
Splitomicin (1-Naphthalenepropanoic Acid) (IC50 of 60 μM), a specific inhibitor of NAD(+)-dependent histone deacetylase Sir2p, displays a high activity in a cell...
|
T3516 |
EDO-S101
|
1236199-60-2
|
98.61%
|
|
EDO-S101 (Tinostamustine) is a pan HDAC inhibitor with IC50 values of 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3 , respectively.
|
T67878 |
HDAC-IN-52
|
2075787-77-6
|
98.5%
|
|
HDAC-IN-52 is a pyridine-containing HDAC inhibitor that inhibits HDAC1, HDAC2, HDAC3 and HDAC10 with IC50s of 0.189, 0.227, 0.440 and 0.446 μM, respectively. HDA...
|
T6865 |
Quisinostat dihydrochloride
|
875320-31-3
|
98.5%
|
|
Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a ...
|
T7691 |
NSC 3852
|
3565-26-2
|
98.44%
|
|
NSC 3852 is a potent inhibitor of histone deacetylase.
|
T0431 |
Abexinostat
|
783355-60-2
|
98.39%
|
|
PCI-24781 (Abexinostat (PCI24781)) is a new pan-HDAC inhibitor mainly targeting HDAC1 (Ki: 7 nM), also have moderate inhibitory for HDACs 2, 3, 6, and 10 and gre...
|
T77334 |
HDAC-IN-57
|
2716217-79-5
|
98.38%
|
|
HDAC-IN-57 is an orally active pan-inhibitor of histone deacetylase (HDAC), inhibiting HDAC1, HDAC2, HDAC6, and HDAC8 with IC50 values of 2.07 nM, 4.71 nM, 2.4 n...
|
T24133 |
HDAC8-IN-20a
|
1884231-52-0
|
98.38%
|
|
HDAC8-IN-20a (HDAC8 inhibitor-20a) is a potent and selective HDAC8 inhibitor with an IC50 of 27 nM. HDAC8-IN-20a blocks activation of growth receptor survival si...
|
T1966 |
Tubastatin A
|
1252003-15-8
|
98.36%
|
|
Tubastatin A (Tubastatin A BASE) is an effective and specific HDAC6 inhibitor (IC50: 15 nM, in a cell-free assay). Its selectivity is 1000-fold against all the o...
|
T6325 |
PCI-34051
|
950762-95-5
|
98.29%
|
|
PCI-34051 is an effective and selective HDAC8 inhibitor (IC50: 10 nM).
|
T10245 |
ACY-957
|
1609389-52-7
|
98.24%
|
|
ACY-957 (HDAC Inhibitor C001) is an orally active and selective inhibitor of HDAC1 and HDAC2 (IC50s: 7 nM, 18 nM, and 1300 nM against HDAC1/2/3) and shows no inh...
|
T10864 |
Corin
|
1808113-09-8
|
98.22%
|
|
Corin is an irreversible inhibitor of HDAC1(IC50 = 147 nM) and LSD1(Ki = 110 nM).
|
T3205 |
UF010
|
537672-41-6
|
98.11%
|
|
UF010 is a potent and selective HADC inhibitor with IC50 ~0.06 μM, 0.1 μM, 0.5 μM and 1.5 μM for HDACs 3, 2, 1 and 8, respectively.
|
T6279 |
Givinostat hydrochloride monohydrate
|
732302-99-7
|
98.09%
|
|
Givinostat hydrochloride monohydrate (ITF2357) is an HDAC inhibitor.
|
T1983 |
CAY10603
|
1045792-66-2
|
98.06%
|
|
CAY10603 (BML-281) is a potent and selective inhibitor of HDAC6.
|
T21806 |
HNHA
|
926908-04-5
|
98.04%
|
|
HNHA is an inhibitor of HDAC.
|
T6279L |
Givinostat hydrochloride
|
199657-29-9
|
98.01%
|
|
Givinostat hydrochloride (ITF2357 hydrochloride) is an inhibitor of HDAC with IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat hydrochloride ...
|
T5631 |
SIS17
|
2374313-54-7
|
98%
|
|
SIS17 is a potent and selective HDAC 11 inhibitor with an IC50 value of 0.83 μM. SIS17, is active in cells and inhibited the demyristoylation of a known HDAC11 s...
|