T10606 |
BRD0705
|
2056261-41-5
|
99.59%
|
|
BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor (IC50: 66 nM; Kd: 4.8 μM). BRD0705 displays increased selectivity for GSK3α (8-fold) ver...
|
T77554 |
GSK-3 Inhibitor 5
|
20099-89-2
|
99.58%
|
|
GSK-3 Inhibitor 5 (4-Cyanophenacyl bromide) is a ketone derivative that is used as an intermediate in pharmaceuticals and organic synthesis, and inhibits glycoge...
|
T41094 |
Wnt/β-catenin agonist 2
|
943820-93-7
|
99.58%
|
|
Wnt/β-catenin agonist 2 activates Wnt/β-catenin signaling and is an effective Wnt agonist. Wnt/β-catenin agonist 2 can be used in the study of diseases related t...
|
T6659 |
SB 415286
|
264218-23-7
|
99.56%
|
|
SB 415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β.
|
T8908 |
4-Chloro-2'-bromoacetophenone
|
536-38-9
|
99.56%
|
|
4-Chloro-2'-bromoacetophenone against glycogen synthase kinase-3 (GSK-3beta).
|
T6206 |
PHA-767491
|
845714-00-3
|
99.49%
|
|
PHA-767491 (CAY10572) is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.
|
T8605 |
GS87
|
919936-70-2
|
99.47%
|
|
GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive differentiation of AML cells.
|
T10705 |
CCG 203769
|
410074-60-1
|
99.46%
|
|
CCG 203769 (Thiadiazolidinone (TDZD) deriv. 6) is a selective inhibitor of RGS4 with an IC50 of 17 nM for the RGS4-Gαo protein-protein interaction.
|
T2695 |
TBB
|
17374-26-4
|
99.45%
|
|
TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).
|
T6049 |
SNS-032
|
345627-80-7
|
99.44%
|
|
SNS-032 (BMS-387032) is a selective inhibitor of CDK2 (IC50: 48 nM ) and is 10- and 20-fold selective over CDK1/CDK4. It is also sensitive to CDK7/9 (IC50: 62 nM...
|
T7426 |
ALSTERPAULLONE
|
237430-03-4
|
99.39%
|
|
Alsterpaullone is a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing Effec
|
T73331 |
GSK3-IN-3
|
331963-27-0
|
99.37%
|
|
GSK3-IN-3 is a mitochondrial autophagy (mitophagy) inducer and GSK-3 inhibitor (IC50: 3.01 μM) that induces parkin-dependent mitochondrial autophagy. GSK3-IN-3 i...
|
T21956 |
GSK3β inhibitor II
|
478482-75-6
|
99.32%
|
|
GSK3β inhibitor II is a GSK3β inhibitor. GSK3β inhibitor II exhibits the research potential of Alzheimer's disease (AD).
|
T14066 |
9-ING-41
|
1034895-42-5
|
99.25%
|
|
9-ING-41 is a glycogen synthase kinase-3 inhibitor.
|
T6139 |
A-674563
|
552325-73-2
|
99.21%
|
|
A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
|
T11447 |
GNF4877
|
2041073-22-5
|
99.11%
|
|
GNF4877 is a potent DYRK1A and GSK3β inhibitor (IC50s: 6 nM and 16 nM). It leads to blockade of nuclear factor of activated T-cells (NFATc) nuclear export and in...
|
T11467 |
GSK-3β inhibitor 1
|
187325-53-7
|
99.08%
|
|
GSK-3β inhibitor 1 is an inhibitor of GSK-3β( IC50 of 4.9 nM) and demonstrates high antidiabetic efficacy.
|
T3074 |
CHIR 98024
|
556813-39-9
|
99.04%
|
|
CHIR 98024 is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 ...
|
T22657 |
Laduviglusib trihydrochloride
|
1782235-14-6
|
99.03%
|
|
Laduviglusib trihydrochloride (CT99021 trihydrochloride) is a selective glycogen synthase kinase 3 (GSK-3) inhibitor with IC50s of 10 nM and 6.7 nM for GSK-3α an...
|
T72048 |
CDK8-IN-12
|
2613307-67-6
|
98.97%
|
|
CDK8-IN-12 is a selective, potent and orally active inhibitor of CDK8 (Ki: 14 nM) and is an anti-cancer agent. CDK8-IN-12 inhibits GSK-3α, GSK-3β and PCK-θ with ...
|