T8958 |
PU-H54
|
1454619-13-6
|
98.42%
|
|
PU-H54 is a purine-based inhibitor of Grp94. It is a Grp94-selective resorcinol-based inhibitor isolated through probing of the exclusive binding region of S2 s...
|
T23434 |
GPR35 agonist 2
|
494191-73-0
|
98.40%
|
|
GPR35 agonist 2 (TC-G 1001) is a potent GPR35 agonist.The EC50 values of GPR35 agonist 2 in the β-arrestin and Ca2+ release assays were 26 and 3.2 nM, respective...
|
TP2073L |
BigLEN (mouse) acetate
|
TP2073L
|
98.34%
|
|
BigLEN (mouse) acetate is a potent and selective agonist of orphan G protein-coupled receptor 171 (GPR171), with a Kd of ∼0.5 nM.
|
T7713 |
Benzyl nicotinate
|
94-44-0
|
98.22%
|
|
Benzyl nicotinate (Pycaril) is a agonist of GPR109A receptor and GPR109B receptor
|
T62420 |
P2Y2R/GPR17 antagonist 1
|
2395016-49-4
|
98.21%
|
|
P2Y2R/GPR17 antagonist 1 (Compound 14m) is a dual P2Y2R (IC50: 3.17 μM) and GPR17 (IC50: 1.67 μM) antagonist.
|
T15364 |
G-1
|
881639-98-1
|
98.14%
|
|
G-1 is a nonsteroidal, high-affinity and selective GPR30 agonist (Ki: 11 nM).
|
TQ0020 |
AMG 837 calcium hydrate
|
1259389-38-2
|
98.07%
|
|
AMG 837 calcium hydrate is a potent GPR40 agonist with an EC50 of 13 nM. AMG 837 calcium hydrate also shows highly selective over GPR41, GPR43, and GPR120 (EC50 ...
|
T77673 |
7-FluorotryptaMine HCl
|
159730-09-3
|
98.06%
|
|
7-FluorotryptaMine HCl is a potent aromatic monoamine GPRC5A agonist that induces GPRC5A-mediated β-arrestin recruitment.7-FluorotryptaMine HCl can be used to st...
|
T14565 |
BI-671800
|
1093108-50-9
|
98.06%
|
|
BI-671800 (AP-761) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2). With IC50 values of 4.5 n...
|
T15432 |
GSK256073
|
862892-90-8
|
98.03%
|
|
GSK256073 is an orally active GPR109A agonist. GSK256073 also is a long-lasting and non-flushing HCA2 (hydroxy-carboxylic acid receptor 2) full agonist (pEC50: 7...
|
T8901 |
YUM70
|
423145-35-1
|
98.01%
|
|
YUM70 is a potent and selective glucose-regulated protein 78 (GRP78) inhibitor(with an IC50 of 1.5 μM for inhibiting GRP78 ATPase activity of the full-length pro...
|
T6855 |
HA15
|
1609402-14-3
|
98%
|
|
HA15 targets specifically BiP/GRP78/HSPA5. HA15 exhibits anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells t...
|
T20939 |
Bimatoprost acid
|
38344-08-0
|
98%
|
|
Bimatoprost acid (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and has a potential antagonistic activity for the FP receptor. It has a relat...
|
T7398 |
ONC212
|
1807861-48-8
|
98%
|
|
ONC212, a fluorinated-ONC201 analogue, is a selective agonist of GPR132.
|
T7261 |
Grp94 Inhibitor-1
|
2234897-35-7
|
98%
|
|
Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM).
|
T7482 |
3-chloro-5-hydroxybenzoic Acid
|
53984-36-4
|
98%
|
|
3-chloro-5-hydroxy Benzoic Acid (3-chloro-5-hydroxy BA) is an agonist of GPR81 (EC50 : 16 μM)
|
T3965 |
Fevipiprant
|
872365-14-5
|
98%
|
|
Fevipiprant (NVP-QAW039) is a selective, potent, reversible competitive CRTh2 antagonist.
|
T5828 |
MS21570
|
65373-29-7
|
98%
|
|
MS21570 as a GPR171 antagonist based on its ability to block,with an IC50 of 220 Nm,that reduces anxiety-like behavior and fear conditioning in mice.
|
T1915 |
AM251
|
183232-66-8
|
97.88%
|
|
AM251 is a effective CB1 receptor antagonist (IC50/Ki: 8 /7.49 nM) that displays 306-fold selectivity over CB2 receptors; also effective GPR55 agonist (EC50: 39 ...
|
TP2165 |
Urotensin II, mouse acetate (9047-55-6 free base)
|
TP2165
|
97.86%
|
|
Urotensin II, mouse acetate (9047-55-6 free base) is an endogenous ligand for the orphan GPR14 or SENR. It is a potent vasoconstrictor.
|