T22967 |
MEDICA16
|
87272-20-6
|
99.13%
|
|
MEDICA16 is a selective agonist for GPR40 as well as a partial agonist for GPR120. MEDICA16, an ATP-citrate lyase inhibitor, significantly reduces intracellular ...
|
T4626L |
TC-O 9311
|
444932-31-4
|
99.12%
|
|
TC-O 9311 (TCO-9311) is an effective agonist of GPR139 (EC50 = 39 nM in CHO-K1 cells expressing human GPR139).
|
T15352 |
FTBMT
|
1358575-02-6
|
99.12%
|
|
FTBMT is a selective GPR52 agonist (EC50: 75 nM) and has antipsychotic and procognitive properties.
|
T21874 |
CID 2745687
|
264233-05-8
|
99.11%
|
|
CID 2745687 is a GPR35 antagonist that inhibited the effects at human GPR35 of cromolyn disodium and zaprinast, two agonists that share an overlapping binding s...
|
TQ0108 |
MK-6892
|
917910-45-3
|
99.03%
|
|
MK-6892 is a selective and full agonist for the high-affinity nicotinic acid receptor GPR109A (Ki: 4 nM; GTPγS EC50: 16 nM).
|
T5100 |
DJ-V-159
|
2253744-53-3
|
99%
|
|
DJ-V-159 is a GPRC6A agonist, targeting the G protein-coupled receptor family C group 6 member A (GPRC6A).
|
T7010 |
VER-155008
|
1134156-31-2
|
98.88%
|
|
VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively, >100-fold se...
|
T9346 |
CVN424
|
2254706-21-1
|
98.8%
|
|
CVN424 is a selective and novel GPR6 Inverse agonist effective in models of Parkinson Disease.
|
T21622 |
Tyrphostin A25
|
118409-58-8
|
98.76%
|
|
Tyrphostin A25 (Tyrphostin AG 82) is a specific EGFR tyrosine kinase inhibitor and GPR35 agonist with an IC50 value of 0.94 μM for GPR35 and an EC50 value of 5.3...
|
T22547 |
Acifran
|
72420-38-3
|
98.65%
|
|
Acifran (AY 25712) is an HM74A/GPR109A and GPR109B agonist and displays antihyperlipidemic activity.
|
T37527L |
[Orn8]-Urotensin II acetate
|
|
98.63%
|
|
[Orn8]-Urotensin II acetate is a Urotensin receptor ligand and a partial agonist at Urotensin receptors.
|
T8407 |
AF64394
|
1637300-25-4
|
98.55%
|
|
AF64394 is a selective inverse agonist of GPR3(pIC50 : 7.3)
|
T9452 |
PW0787
|
2624131-45-7
|
98.52%
|
|
PW0787 is a potent, selective, orally active, and brain-penetrant GPR52 agonist (EC50=135 nM).
|
T2058 |
Palosuran
|
540769-28-6
|
98.46%
|
|
Palosuran (ACT-058362) (ACT-058362) is a new potent and specific antagonist of the human UT receptor.
|
T8958 |
PU-H54
|
1454619-13-6
|
98.42%
|
|
PU-H54 is a purine-based inhibitor of Grp94. It is a Grp94-selective resorcinol-based inhibitor isolated through probing of the exclusive binding region of S2 s...
|
TP2073L |
BigLEN (mouse) acetate
|
TP2073L
|
98.34%
|
|
BigLEN (mouse) acetate is a potent and selective agonist of orphan G protein-coupled receptor 171 (GPR171), with a Kd of ∼0.5 nM.
|
T7713 |
Benzyl nicotinate
|
94-44-0
|
98.22%
|
|
Benzyl nicotinate (Pycaril) is a agonist of GPR109A receptor and GPR109B receptor
|
T62420 |
P2Y2R/GPR17 antagonist 1
|
2395016-49-4
|
98.21%
|
|
P2Y2R/GPR17 antagonist 1 (Compound 14m) is a dual P2Y2R (IC50: 3.17 μM) and GPR17 (IC50: 1.67 μM) antagonist.
|
T15364 |
G-1
|
881639-98-1
|
98.14%
|
|
G-1 is a nonsteroidal, high-affinity and selective GPR30 agonist (Ki: 11 nM).
|
TQ0020 |
AMG 837 calcium hydrate
|
1259389-38-2
|
98.07%
|
|
AMG 837 calcium hydrate is a potent GPR40 agonist with an EC50 of 13 nM. AMG 837 calcium hydrate also shows highly selective over GPR41, GPR43, and GPR120 (EC50 ...
|