T28303 |
Pazinaclone
|
103255-66-9
|
98.12%
|
|
Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.
|
T0958 |
Penicillin G sodium salt
|
69-57-8
|
98.11%
|
|
Penicillin G sodium(Benzylpenicillin sodium) salt is a penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a var...
|
T16535 |
Picrotoxinin
|
17617-45-7
|
98.07%
|
|
Picrotoxinin is a blocker of chloride channel and a noncompetitive antagonist of GABAA with an IC50 of 1.15 μM for α1β2γ2L GABAA. Picrotoxinin shows convulsant p...
|
T22348 |
Isonipecotic acid
|
498-94-2
|
98.02%
|
|
Isonipecotic acid (4-Piperidinecarboxylic acid) is a heterocyclic compound. Isonipecotic acid mainly characterized as a GABAA receptor partial agonist.
|
TN1202 |
(-)-α-Pinene
|
7785-26-4
|
98.02%
|
|
(-)-α-Pinene ((1S)-(-)-Alpha-Pinene) enhances the quantity of NREMS without affecting the intensity of NREMS by prolonging GABAergic synaptic transmission, actin...
|
T3403 |
Glabridin
|
59870-68-7
|
98.01%
|
|
Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS und...
|
T23466 |
TP003
|
628690-75-5
|
98%
|
|
TP003 is a novel non-selective GABAA receptor benzodiazepine site agonist with affinity for α1β2gam2, α2β3gam2, α3β3gam2, α5β2gam2, EC50 of 20.3, 10.6, 3.24, 5.6...
|
T7136 |
AZD-6280
|
942436-93-3
|
98%
|
|
AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder.
|
T4590 |
(+)-Kavain
|
500-64-1
|
98%
|
|
(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.
|
T0675 |
Topiramate
|
97240-79-4
|
98%
|
|
Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associate...
|
T7165 |
Basmisanil
|
1159600-41-5
|
98%
|
|
Basmisanil (RG1662) is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for the tre...
|
T0508 |
γ-Aminobutyric acid
|
56-12-2
|
98%
|
|
γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system.
|
T7595 |
L-DABA
|
1758-80-1
|
98%
|
|
L-DABA (L-2,4-Diaminobutyric acid) is an inhibitor of GABA transaminase (IC50 > 500 μM).
|
T5754 |
Kavain
|
3155-48-4
|
98%
|
|
Kavain, a compound extracted from the Kava plant, Piper methysticum, is found to be involved in TNF-α expression in human and mouse cells via regulation of trans...
|
T27838 |
Lirequinil
|
143943-73-1
|
97.86%
|
|
Lirequinil (Ro 41-3696) is a small molecule GABAA receptor agonist used to study neurological disorders.
|
TN1432 |
Bacopasaponin C
|
178064-13-6
|
97.85%
|
|
Bacopasaponin C may have antioxidant activity, it also shows anti-leishmanial property.
|
T4522 |
SSD114 HCl
|
2319790-02-6
|
97.83%
|
|
SSD114 is a novel GABAB receptor positive allosteric modulator.
|
T2196 |
Fipronil
|
120068-37-3
|
97.48%
|
|
Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disr...
|
T5S1882 |
Songorine
|
509-24-0
|
97.34%
|
|
Songorine (Napellonine) shows favorable anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking...
|
T28159 |
Nerisopam
|
102771-12-0
|
97.27%
|
|
Nerisopam is an agonist of gamma-aminobutyric acid (GABA) receptor.
|