Home Tools
Log in
Cart

GABA Receptor

The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T28303 Pazinaclone 103255-66-9 98.12%
Pazinaclone
Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.
T0958 Penicillin G sodium salt 69-57-8 98.11%
Penicillin G sodium salt
Penicillin G sodium(Benzylpenicillin sodium) salt is a penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a var...
T16535 Picrotoxinin 17617-45-7 98.07%
Picrotoxinin
Picrotoxinin is a blocker of chloride channel and a noncompetitive antagonist of GABAA with an IC50 of 1.15 μM for α1β2γ2L GABAA. Picrotoxinin shows convulsant p...
T22348 Isonipecotic acid 498-94-2 98.02%
Isonipecotic acid
Isonipecotic acid (4-Piperidinecarboxylic acid) is a heterocyclic compound. Isonipecotic acid mainly characterized as a GABAA receptor partial agonist.
TN1202 (-)-α-Pinene 7785-26-4 98.02%
(-)-α-Pinene
(-)-α-Pinene ((1S)-(-)-Alpha-Pinene) enhances the quantity of NREMS without affecting the intensity of NREMS by prolonging GABAergic synaptic transmission, actin...
T3403 Glabridin 59870-68-7 98.01%
Glabridin
Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS und...
T23466 TP003 628690-75-5 98%
TP003
TP003 is a novel non-selective GABAA receptor benzodiazepine site agonist with affinity for α1β2gam2, α2β3gam2, α3β3gam2, α5β2gam2, EC50 of 20.3, 10.6, 3.24, 5.6...
T7136 AZD-6280 942436-93-3 98%
AZD-6280
AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder.
T4590 (+)-Kavain 500-64-1 98%
(+)-Kavain
(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.
T0675 Topiramate 97240-79-4 98%
Topiramate
Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associate...
T7165 Basmisanil 1159600-41-5 98%
Basmisanil
Basmisanil (RG1662) is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for the tre...
T0508 γ-Aminobutyric acid 56-12-2 98%
γ-Aminobutyric acid
γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system.
T7595 L-DABA 1758-80-1 98%
L-DABA
L-DABA (L-2,4-Diaminobutyric acid) is an inhibitor of GABA transaminase (IC50 > 500 μM).
T5754 Kavain 3155-48-4 98%
Kavain
Kavain, a compound extracted from the Kava plant, Piper methysticum, is found to be involved in TNF-α expression in human and mouse cells via regulation of trans...
T27838 Lirequinil 143943-73-1 97.86%
Lirequinil
Lirequinil (Ro 41-3696) is a small molecule GABAA receptor agonist used to study neurological disorders.
TN1432 Bacopasaponin C 178064-13-6 97.85%
Bacopasaponin C
Bacopasaponin C may have antioxidant activity, it also shows anti-leishmanial property.
T4522 SSD114 HCl 2319790-02-6 97.83%
SSD114 HCl
SSD114 is a novel GABAB receptor positive allosteric modulator.
T2196 Fipronil 120068-37-3 97.48%
Fipronil
Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disr...
T5S1882 Songorine 509-24-0 97.34%
Songorine
Songorine (Napellonine) shows favorable anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking...
T28159 Nerisopam 102771-12-0 97.27%
Nerisopam
Nerisopam is an agonist of gamma-aminobutyric acid (GABA) receptor.
Pazinaclone
T28303
Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.
Penicillin G sodium salt
T0958
Penicillin G sodium(Benzylpenicillin sodium) salt is a penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a var...
Picrotoxinin
T16535
Picrotoxinin is a blocker of chloride channel and a noncompetitive antagonist of GABAA with an IC50 of 1.15 μM for α1β2γ2L GABAA. Picrotoxinin shows convulsant p...
Isonipecotic acid
T22348
Isonipecotic acid (4-Piperidinecarboxylic acid) is a heterocyclic compound. Isonipecotic acid mainly characterized as a GABAA receptor partial agonist.
(-)-α-Pinene
TN1202
(-)-α-Pinene ((1S)-(-)-Alpha-Pinene) enhances the quantity of NREMS without affecting the intensity of NREMS by prolonging GABAergic synaptic transmission, actin...
Glabridin
T3403
Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS und...
TP003
T23466
TP003 is a novel non-selective GABAA receptor benzodiazepine site agonist with affinity for α1β2gam2, α2β3gam2, α3β3gam2, α5β2gam2, EC50 of 20.3, 10.6, 3.24, 5.6...
AZD-6280
T7136
AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder.
(+)-Kavain
T4590
(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.
Topiramate
T0675
Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associate...
Basmisanil
T7165
Basmisanil (RG1662) is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for the tre...
γ-Aminobutyric acid
T0508
γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system.
L-DABA
T7595
L-DABA (L-2,4-Diaminobutyric acid) is an inhibitor of GABA transaminase (IC50 > 500 μM).
Kavain
T5754
Kavain, a compound extracted from the Kava plant, Piper methysticum, is found to be involved in TNF-α expression in human and mouse cells via regulation of trans...
Lirequinil
T27838
Lirequinil (Ro 41-3696) is a small molecule GABAA receptor agonist used to study neurological disorders.
Bacopasaponin C
TN1432
Bacopasaponin C may have antioxidant activity, it also shows anti-leishmanial property.
SSD114 HCl
T4522
SSD114 is a novel GABAB receptor positive allosteric modulator.
Fipronil
T2196
Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disr...
Songorine
T5S1882
Songorine (Napellonine) shows favorable anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking...
Nerisopam
T28159
Nerisopam is an agonist of gamma-aminobutyric acid (GABA) receptor.
1 2 3 4 5 6 7 8 9 10
TargetMol