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Ferroptosis

Ferroptosis is a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides, and is genetically and biochemically distinct from other forms of regulated cell death such as apoptosis.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T1085 L-Glutathione reduced 70-18-8 98.72%
L-Glutathione reduced
L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals. L-Glutat...
T8922 SRS11-92 1467047-25-1 98.67%
SRS11-92
SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1
T77765 FSEN1 862808-01-3 98.56%
FSEN1
FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM. FSEN1 induces iron death in cancer cells by inhibiting FSP1. F...
T5343 UAMC-3203 2271358-64-4 98.55%
UAMC-3203
UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).
T2707 Pifithrin-α hydrobromide 63208-82-2 98.54%
Pifithrin-α hydrobromide
Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.
TQ0120 CDDO-Im 443104-02-7 98.3%
CDDO-Im
CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).
T7092 NADPH tetrasodium salt 2646-71-1 98.22%
NADPH tetrasodium salt
NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of ...
T0423 Ethylenediaminetetraacetic acid trisodium salt 150-38-9 98%
Ethylenediaminetetraacetic acid trisodium salt
Ethylenediaminetetraacetic acid trisodium salt (EDTA Trisodium) used to bind metal ions in the chelation therapy.
T2856 (-)-Epicatechin 490-46-0 98%
(-)-Epicatechin
(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization o...
T1502 Vildagliptin 274901-16-5 98%
Vildagliptin
Vildagliptin (LAF237) is a cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Vildagliptin's cy...
T5679 (E)-Ferulic acid 537-98-4 98%
(E)-Ferulic acid
(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of ...
T5364 TBHQ 1948-33-0 98%
TBHQ
TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.
T6243 U-73122 112648-68-7 97.98%
U-73122
U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.
T4066 FIN56 1083162-61-1 97.86%
FIN56
FIN56 is a specific inducer of ferroptosis.
T16540 Piperazine Erastin 1538593-71-3 97.74%
Piperazine Erastin
Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.
TJS1159 Chrysosplenetin 603-56-5 97.43%
Chrysosplenetin
Chrysosplenetin is a metabolic inhibitor of artemisinin.
T2858 Baicalein 491-67-8 97.25%
Baicalein
Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.
T8375 ML-210 1360705-96-9 97%
ML-210
ML-210 (CID 49766530) is a selective RAS and covalent glutathione peroxidase 4 (GPX4) inhibitor(GPX4, EC50 : 30 nM), with anti-cancer activity
T0392 Artemisinin 63968-64-9 97%
Artemisinin
Artemisinin (Qinghaosu) is an ancient Chinese herbal therapy for malarial fevers which has been recently found to have potent activity against many forms of mala...
T2870 Matrine 519-02-8 100%
Matrine
Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.
L-Glutathione reduced
T1085
L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals. L-Glutat...
SRS11-92
T8922
SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1
FSEN1
T77765
FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM. FSEN1 induces iron death in cancer cells by inhibiting FSP1. F...
UAMC-3203
T5343
UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).
Pifithrin-α hydrobromide
T2707
Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.
CDDO-Im
TQ0120
CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).
NADPH tetrasodium salt
T7092
NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of ...
Ethylenediaminetetraacetic acid trisodium salt
T0423
Ethylenediaminetetraacetic acid trisodium salt (EDTA Trisodium) used to bind metal ions in the chelation therapy.
(-)-Epicatechin
T2856
(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization o...
Vildagliptin
T1502
Vildagliptin (LAF237) is a cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Vildagliptin's cy...
(E)-Ferulic acid
T5679
(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of ...
TBHQ
T5364
TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.
U-73122
T6243
U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.
FIN56
T4066
FIN56 is a specific inducer of ferroptosis.
Piperazine Erastin
T16540
Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.
Chrysosplenetin
TJS1159
Chrysosplenetin is a metabolic inhibitor of artemisinin.
Baicalein
T2858
Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.
ML-210
T8375
ML-210 (CID 49766530) is a selective RAS and covalent glutathione peroxidase 4 (GPX4) inhibitor(GPX4, EC50 : 30 nM), with anti-cancer activity
Artemisinin
T0392
Artemisinin (Qinghaosu) is an ancient Chinese herbal therapy for malarial fevers which has been recently found to have potent activity against many forms of mala...
Matrine
T2870
Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.
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TargetMol