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Ferroptosis

Ferroptosis is a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides, and is genetically and biochemically distinct from other forms of regulated cell death such as apoptosis.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T0334 Rosiglitazone 122320-73-4 99.87%
Rosiglitazone
Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity. Rosiglitazone is also a hypoglycemic agent and a thiazolidi...
T9073 SRS16-86 1793052-96-6 99.85%
SRS16-86
SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.
T2O2733 L-Cystine 56-89-3 99.85%
L-Cystine
L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation of cyste...
T60168 NCOA4 - 9a 2650557-72-3 99.84%
NCOA4 - 9a
NCOA4 - 9a is a ferroptosis inhibitor.
TQ0211 Brusatol 14907-98-3 99.82%
Brusatol
Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.
T3S1447 Arteannuin B 50906-56-4 99.8%
Arteannuin B
1. Arteannuin B has potent antimalarial activity.
T1710 Trolox 53188-07-1 99.8%
Trolox
Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.
T1637 Deferoxamine Mesylate 138-14-7 99.8%
Deferoxamine Mesylate
Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor. Deferoxamine Mesylate binds free iron into a stable complex and reduces iron accumulat...
T6646 Rosiglitazone hydrochloride 302543-62-0 99.79%
Rosiglitazone hydrochloride
Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.
T8970 ML162 1035072-16-2 99.78%
ML162
ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-typ...
T36404L PRLX-93936 HCL 1094210-96-4 99.78%
PRLX-93936 HCL
PRLX-93936 HCL is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.
T6192 Alogliptin 850649-61-5 99.77%
Alogliptin
Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9....
T7530 PD146176 4079-26-9 99.77%
PD146176
PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM. PD146176 reverses...
T1644 Dopamine hydrochloride 62-31-7 99.76%
Dopamine hydrochloride
Dopamine hydrochloride (ASL279) is a naturally occurring catecholamine formed by decarboxylation of dihydroxyphenylalanine and a precursor of norepinephrine and ...
T64357 FA16 99.75%
FA16
FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16 inhibit...
T11631 IFSP1 150651-39-1 99.74%
iFSP1
iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverse huma...
T1297 Eugenol 97-53-0 99.72%
Eugenol
Eugenol (Allylguaiacol) is a Standardized Chemical Allergen. The physiologic effect of eugenol is by means of Increased Histamine Release and Cell-mediated Immun...
T5687 WITHAFERIN A 5119-48-2 99.71%
WITHAFERIN A
WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/or...
T2A2497 L-Glutamic acid 56-86-0 99.7%
L-Glutamic acid
L-Glutamic acid (Glutaminol) acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals.
T0787 Butylhydroxyanisole 25013-16-5 99.7%
Butylhydroxyanisole
Butylhydroxyanisole (BHA) is an antioxidant consisting of a mixture of two isomeric organic compounds, 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyan...
Rosiglitazone
T0334
Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity. Rosiglitazone is also a hypoglycemic agent and a thiazolidi...
SRS16-86
T9073
SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.
L-Cystine
T2O2733
L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation of cyste...
NCOA4 - 9a
T60168
NCOA4 - 9a is a ferroptosis inhibitor.
Brusatol
TQ0211
Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.
Arteannuin B
T3S1447
1. Arteannuin B has potent antimalarial activity.
Trolox
T1710
Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.
Deferoxamine Mesylate
T1637
Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor. Deferoxamine Mesylate binds free iron into a stable complex and reduces iron accumulat...
Rosiglitazone hydrochloride
T6646
Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.
ML162
T8970
ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-typ...
PRLX-93936 HCL
T36404L
PRLX-93936 HCL is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.
Alogliptin
T6192
Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9....
PD146176
T7530
PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM. PD146176 reverses...
Dopamine hydrochloride
T1644
Dopamine hydrochloride (ASL279) is a naturally occurring catecholamine formed by decarboxylation of dihydroxyphenylalanine and a precursor of norepinephrine and ...
FA16
T64357
FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16 inhibit...
iFSP1
T11631
iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverse huma...
Eugenol
T1297
Eugenol (Allylguaiacol) is a Standardized Chemical Allergen. The physiologic effect of eugenol is by means of Increased Histamine Release and Cell-mediated Immun...
WITHAFERIN A
T5687
WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/or...
L-Glutamic acid
T2A2497
L-Glutamic acid (Glutaminol) acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals.
Butylhydroxyanisole
T0787
Butylhydroxyanisole (BHA) is an antioxidant consisting of a mixture of two isomeric organic compounds, 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyan...
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TargetMol