T8317 |
5'-Fluoroindirubinoxime
|
861214-33-7
|
100%
|
|
5'-Fluoroindirubinoxime (5'-FIO) is a potent FLT3 inhibitor( IC50 : 15 nM).
|
T7104 |
Dovitinib lactate
|
692737-80-7
|
100%
|
|
Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).
|
TQ0317 |
R1530
|
882531-87-5
|
|
|
R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.
|
TQ0235 |
AC710
|
1351522-04-7
|
|
|
AC710 is a potent PDGFR inhibitor (Kds: 0.6, 1, 1.57, 1.3, 1 nM for FLT3, KIT, CSF1R, PDGFRα and PDGFRβ).
|
T6S0033 |
Crotonoside
|
1818-71-9
|
|
|
1. Crotonoside (Isoguanosine) has much more active than adenosine in reducing the blood pressure in rabbits and cats, in decreasing the tone of isolated intestin...
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T2116 |
AEE788
|
497839-62-0
|
|
|
AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.
|
T14072 |
A-443654
|
552325-16-3
|
|
|
A-443654 is a pan-Akt inhibitor. A-443654 has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM).
|
T7673 |
ATH686
|
853299-52-2
|
|
|
ATH686 is an potent and selective Inhibitor of FLT3.
|
T10531 |
BGB-102
|
807640-87-5
|
98%
|
|
BGB-102 (JNJ-26483327) is a kinase inhibitor targeting FLT3 and YES1 and an antagonist targeting EGFR and VEGFR3, which may be useful in the study of macular deg...
|
T2272 |
BPR1J-097
|
1327167-19-0
|
98%
|
|
BPR1J-097) is a novel FLT-3 inhibitor(IC50: 11±7 nM) with promising in vivo anti-tumor activities. It also inhibits FLT-3 D835Y (IC50: 3 nM).
|
T4261 |
BPR1J-097 hydrochloride (1327167-19-0(free base))
|
T4261
|
98%
|
|
BPR1J-097, a new-type small molecule FLT-3 inhibitor(IC50=11±7 nM), is with great anti-tumor activities in vivo.
|
T2051 |
SKLB4771
|
1370256-78-2
|
98%
|
|
SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.
|