T4318 |
EOC317
|
939805-30-8
|
98.00%
|
|
EOC317 (ACTB-1003) is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).
|
T3456 |
Fisogatinib
|
1707289-21-1
|
98%
|
|
Fisogatinib (BLU-554) is a potent inhibitor of fibroblast growth factor receptor 4 (FGFR4).
|
T2358 |
ENMD-2076
|
934353-76-1
|
98%
|
|
ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.
|
T6082 |
SSR128129E
|
848318-25-2
|
98%
|
|
SSR128129E (SSR) is an allosteric and orally-active FGFR1 inhibitor (IC50: 1.9 μM), but not affecting other related RTKs.
|
T3466 |
FIIN-3
|
1637735-84-2
|
97.7%
|
|
FIIN-3 is an irreversible inhibitor of FGFR.
|
T3274 |
S49076
|
1265965-22-7
|
97.4%
|
|
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3, blocking cellular phosphorylation of MET, AXL, and FGFRs.
|
T4235 |
Roblitinib
|
1708971-55-4
|
97.36%
|
|
Roblitinib (FGF-401) is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, Roblitini...
|
T37426 |
FIIN-1
|
1256152-35-8
|
97.30%
|
|
FIIN-1 (FGFR irreversible inhibitor-1) is an irreversible and selective FGFR inhibitor with Kd of 2.8, 6.9, 5.4, 120, 32 and 120 nM for FGFR1, FGFR2, FGFR3, FGFR...
|
T2608 |
CHIR-98014
|
252935-94-7
|
97.09%
|
|
CHIR-98014 (CT98014) is a selective GSK3 inhibitor; potentiate insulin activation of glucose transport and utilization in vitro and in vivo.
|
T26240 |
Surfen dihydrochloride
|
5424-37-3
|
97.08%
|
|
Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a potent small molecule antagonist of heparin sulfate with antibacterial and antiviral activity, and i...
|
T24804 |
SM27
|
6266-54-2
|
96.8%
|
|
SM27 is a fibroblast growth factor 2 (FGF2) inhibitor with anti-angiogenic activity and can be used to study tumours.
|
T8976 |
PD-089828
|
179343-17-0
|
96.78%
|
|
PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 µM, respectively) and a noncompetitiv...
|
T15185 |
Lucitanib
|
1058137-23-7
|
96.13%
|
|
Lucitanib (E-3810) is a novel VEGFR and FGFR inhibitor. It potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1 and FGFR2 (IC50s: 7 nM, 25 nM, 10 nM, ...
|
T6184 |
Orantinib
|
252916-29-3
|
100%
|
|
Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation. It ...
|
T2S0007 |
Ferulic acid sodium
|
24276-84-4
|
100%
|
|
Ferulic acid sodium (Sodium ferulic), the sodium salt of ferulic acid, is a drug used in traditional Chinese medicine for treatment of cardiovascular and cerebro...
|
T27319 |
FIIN-4
|
2093088-81-2
|
100%
|
|
FIIN-4 is a covalent inhibitor of FGFR and can be used in studies about metastatic breast cancer.
|
T2372L |
Ponatinib Hydrochloride
|
1114544-31-8
|
100%
|
|
Ponatinib Hydrochloride (AP-24534 Hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.3...
|
T7104 |
Dovitinib lactate
|
692737-80-7
|
100%
|
|
Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).
|
T9030 |
SU4984
|
186610-89-9
|
100%
|
|
SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).
|
TQ0317 |
R1530
|
882531-87-5
|
|
|
R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.
|