T4606 |
2119738-71-3
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2119738-71-3
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99.23%
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2119738-71-3 is a useful organic compound for research related to life sciences. The catalog number is T4606 and the CAS number is 2119738-71-3.
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T64167 |
Ifebemtinib
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1227948-82-4
|
98.33%
|
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Ifebemtinib (BI-853520) is an orally active and potent inhibitor of adhesion plaque kinase (FAK) (IC50=1 nM) with anti-tumour activity that inhibits globule form...
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T15092 |
Defactinib hydrochloride
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1073160-26-5
|
98.06%
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Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK. Which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-depen...
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T79688 |
FAK-IN-11
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98%
|
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FAK-IN-11 (Compound 4l), a FAK inhibitor, specifically targets the ATP binding pocket of FAK to prevent its phosphorylation. It exhibits cytotoxic effects on MDA...
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T82420 |
FAK-IN-12
|
|
98%
|
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FAK-IN-12 (Compound 12S) is a selective FAK inhibitor with an IC50 of 47 nM. It effectively suppresses proliferation of MGC-803, HCT-116, and KYSE30 cells with I...
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T6936 |
PF-03814735
|
942487-16-3
|
98%
|
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PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and...
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TN3139 |
5α-Hydroxycostic acid
|
132185-83-2
|
98%
|
|
5alpha-Hydroxycostic acid possesses anti-angiogenic ability by interfering the VEGF- and Ang2-related pathways, and it may be a good drug candidate.
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T11260 |
FAK inhibitor 2
|
2354405-14-2
|
98%
|
|
FAK inhibitor 2, antitumor and anti-angiogenesis activitiesis ,is a potent focal adhesion kinase (FAK) inhibitor with an IC50 of 0.07 nM .
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TN4046 |
Excisanin A
|
78536-37-5
|
98%
|
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ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a pote...
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T2609 |
Masitinib
|
790299-79-5
|
99.91%
|
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Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs. Since its introduction in November 200...
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TQ0169 |
Inulicin
|
33627-41-7
|
99.77%
|
|
Inulicin (1-O-Acetylbritannilactone), an active compound isolated from Inula Britannica L, inhibits VEGF-mediated activation of Src and FAK.
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T1950 |
PND-1186
|
1061353-68-1
|
99.75%
|
|
PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).
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T9576 |
AMP-945
|
1393653-34-3
|
99.60%
|
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AMP-945 is a proprietary focal adhesion kinase (FAK) inhibitor.
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T2809 |
(R)-Fangchinoline
|
33889-68-8
|
99.58%
|
|
(R)-Fangchinoline ((+)-Thalrugosine) is extracted from Stephania tetrandra S. Moore.
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T3391 |
Corosolic acid
|
4547-24-4
|
99.52%
|
|
Corosolic acid (Colosic acid) contains anti-angiogenic activity that can suppress FAK signaling induced by angiopoietin-1. Corosolic acid exerts anticancer activ...
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T6177 |
PF-562271 besylate
|
939791-38-5
|
99.5%
|
|
PF-562271 besylate (PF-00562271 Besylate) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK a...
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T0263 |
Chloropyramine hydrochloride
|
6170-42-9
|
99.45%
|
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Chloropyramine hydrochloride (Alergosan) is a histamine receptor H1 antagonist.
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T67843 |
GSK215
|
2743427-26-9
|
99.3%
|
|
GSK215 is a potent and selective PROTAC focal adhesion kinase (FAK) degrader (pDC50= 8.4). GSK215 is designed by the FAK inhibitor VS-4718 and a binder for the V...
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T6419 |
BMS-536924
|
468740-43-4
|
99.19%
|
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BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for ...
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TN1433 |
Batatasin III
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56684-87-8
|
99.16%
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Batatasin III inhibits cancer migration and invasion by suppressing epithelial to mesenchymal transition and FAK-AKT signals and possesses anti-cancer activities...
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