Estrogen Receptor/ERR

The ERRs are orphan nuclear receptors, meaning the identity of their endogenous ligand has yet to be unambiguously determined. They are named because of sequence homology with estrogen receptors, but do not appear to bind estrogens or other tested steroid hormones.There are three human estrogen related receptors:ERRα,ERRβand ERRγ .

Cat. No.	Product name	CAS No.	Purity
TMA1644	Segetalin B	164991-89-3	99.64%
TMA1644	Segetalin B is a natural product from Vaccaria segetalis (Neck.) Garcke, has estrogen-like activity.
T2837	Chrysin	480-40-0	99.63%
T2837	Chrysin (5,7-Dihydroxyflavone) exhibits many biological activities and pharmacological effects, including antioxidant, anti-inflammatory, anticancer, and antivir...
T6491	(-)-(S)-Equol	531-95-3	99.61%
T6491	(-)-(S)-Equol (4',7-Dihydroxyisoflavan) is an orally bioavailable, non-steroidal estrogen naturally produced by the metabolism of the isoflavonoid daidzein by hu...
T11237	Camizestrant	2222844-89-3	99.57%
T11237	Camizestrant (Estrogen receptor antagonist 2) is an antagonist of the estrogen receptor and can be used in studies about ER+ HER2-advanced breast cancer[1].
T4420	4-Hydroxytamoxifen	68047-06-3	99.56%
T4420	4-Hydroxytamoxifen (ICI 79280) is the active metabolite of Tamoxifen, an estrogen receptor modulator (SERM) with selective and oral potency. 4-Hydroxytamoxifen h...
T3958	WAY-200070	440122-66-7	99.46%
T3958	WAY-200070 is a specific agonist of estrogen receptor β (ERRβ, IC50: 2.3 nM).
T15191	PROTAC ERRα ligand 1	1264754-13-3	99.45%
T15191	PROTAC ERRα ligand 1 is an α (ERRα) antagonist of estrogen-related receptor (IC50s of 0.04 and 2.8 μM for ERRα and ERRγ, respectively).
T40598	Norethindrone acetate	51-98-9	99.4%
T40598	Norethindrone acetate (19-Norethindroneacetate) is an oestrogen with inhibitory effects on adolescent menstruation and hepatic adenomas and is often used in comb...
T14987	CMP8	851107-28-3	99.38%
T14987	CMP8 is a selective ligand for estrogen receptor. CMP8 binds to the mutant estrogen receptor ligand binding domain (ERLBD). CMP8 has IC50 values of 29 nM , 41 nM...
T36857L	Premarin	481-97-0	99.37%
T36857L	Premarin (Estrone 3-sulfate) is an an estrogen sulfate with neuroprotective actions during traumatic brain injury.
T11098	Droloxifene	82413-20-5	99.37%
T11098	Droloxifene (3-Hydroxytamoxifen), a tamoxifen derivative, is an oral active and selective estrogen receptor modulator.Droloxifene induced p53 expression and apop...
T4388	PHTPP	805239-56-9	99.37%
T4388	PHTPP is a selective ERβ antagonist.
T1048	Estradiol	50-28-2	99.35%
T1048	Estradiol (E2) is a naturally occurring steroidal sex hormone that is essential for female fertility and maintenance of secondary sexual characteristics. Estradi...
T12148	N-Desmethyltamoxifen hydrochloride	15917-65-4	99.34%
T12148	N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.
TQ0295	Coumestrol	479-13-0	99.23%
TQ0295	Coumestrol that existed in soybean products suppresses the proliferation of ES2 cells (IC50: 50 μM). It exhibits activities against neurological disorders, cance...
T0168	Estradiol (cypionate)	313-06-4	99.2%
T0168	Estradiol cypionate (Depofemin), the 17 β-cyclopentylpropinate ester of estradiol, inhibits ET-1 synthesis via estrogen receptor.
T6533	Hexestrol	84-16-2	99.2%
T6533	Hexestrol (Hexanoestrol) binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively.
T0695	Avobenzone	70356-09-1	99.14%
T0695	Avobenzone (Butyl methoxydibenzoylmethane), an oil-soluble ingredient, is a dibenzoylmethane derivative used in sunscreen products to absorb the full spectrum of...
T1216	Diethylstilbestrol	56-53-1	99.13%
T1216	Diethylstilbestrol (DES) is used in the treatment of menopausal and postmenopausal disorders.
T2177	Kaempferol	520-18-3	99.11%
T2177	Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ. Kaempferol has a wide range of antitumor, anti-inflammatory, antioxidant, ...