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Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as sex, age, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T66935 1-Aminopropan-2-ol 78-96-6 98%
1-Aminopropan-2-ol
1-Aminopropan-2-ol is involved in the metabolism of threonine in Bacillus subtilis strains and can be used as a nitrogen source on fungal media.
TQ0148 Orotidine 314-50-1 98%
Orotidine
Orotidine (Uridin-6-carboxylic acid) is a nucleoside found in bacteria, fungi, and plants. In humans, orotidine occurs as its 5'-phosphate (orotidylic acid).
T10934 D-Gluconic acid 526-95-4 98%
D-Gluconic acid
D-Gluconic acid (D-Gluco-hexonic acid) is a carboxylic acid that has antiseptic and chelating properties through oxidation.
T9454 4-Hydroxyestrone 3131-23-5 98%
4-Hydroxyestrone
4-Hydroxyestrone, an endogenous estrogen metabolite, can strongly protect neuronal cells against oxidative damage.
T21411 Isoproterenol 7683-59-2 98%
Isoproterenol
Isoproterenol (Norisodrine) is a non-selective and orally active β-adrenoceptor agonist.Isoproterenol is a potent peripheral vasodilator and bronchodilator.Isopr...
T35321 Zymostenol 566-97-2 98%
Zymostenol
Zymostenol (5a-Cholest-8-en-3b-ol) is a RORγ agonist with an EC50 of 1 μM.Zymostenol is a late stage precursor of cholesterol biosynthesis.
T10943 D-(-)-Lactic acid 10326-41-7 98%
D-(-)-Lactic acid
D-(-)-Lactic acid is a normal intermediate in sugar fermentation (oxidation, metabolism). It is identified as a competitive inhibitor of ProDH (proline dehydroge...
T5066 Nε,Nε,Nε-Trimethyllysine chloride 55528-53-5 98%
Nε,Nε,Nε-Trimethyllysine chloride
Nε,Nε,Nε-Trimethyllysine chloride (Lys(Me)3-OH Chloride) is a methylated derivative of the amino acid lysine. It is a component of histone proteins, a precursor ...
T13831 Prostaglandin D2 41598-07-6 98%
Prostaglandin D2
Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals,and is a potent endogenous sleep promoting substances.
T17056 Tetrahydrobiopterin 17528-72-2 98%
Tetrahydrobiopterin
Tetrahydrobiopterin (BH4) is a cofactor for aromatic amino acid hydroxylases and an essential cofactor for nitric oxide synthase (NOS), which is used in the stud...
T67670 4-Ethylbenzaldehyde 4748-78-1 98%
4-Ethylbenzaldehyde
4-Ethylbenzaldehyde is a RIFM flavor present in naturally fermented tilapia sausage and soybean plants.4-Ethylbenzaldehyde shows nematicidal activity at 250 g/ml...
T40849 C20 Ceramide 7344-02-7 98%
C20 Ceramide
C20 Ceramide (N-Arachidoyl-D-sphingosine) is a 20:0 ceramide found in the brain that crosses the blood-brain barrier to activate microglia and induce depressive-...
T8269 3-Methoxytyramine 554-52-9 98%
3-Methoxytyramine
3-Methoxytyramine, an extracellular metabolite of 3-hydroxytyramine/dopamine, is a neuromodulator.
T37323 Succinyl-Coenzyme A sodium salt 108347-97-3 98%
Succinyl-Coenzyme A sodium salt
Succinyl-Coenzyme A sodium salt(Succinyl-CoA sodium salt) participates in the citric acid cycle, where it is converted to succinic acid.Succinyl-Coenzyme A (sodi...
TN6699 DL-Malic acid 617-48-1 BR
DL-Malic acid
DL-Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid found in fruits such as apples and pears. It plays a role in many sour or acidic foods.
T0848 L-DOPA 59-92-7 99.99%
L-DOPA
L-DOPA (Levodopa) is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxyl...
T2876 Flavone 525-82-6 99.99%
Flavone
Flavone (2-Phenyl-4-chromone) have effects on CYP (P450) activity which are enzymes that metabolize most drugs in the body.
T8783 4-Methylbiphenyl 644-08-6 99.98%
4-Methylbiphenyl
4-Methylbiphenyl (4-Phenyltoluene) is a human endogenous metabolite.
T8105 Indole-3-carboxaldehyde 487-89-8 99.98%
Indole-3-carboxaldehyde
1H-Indole-3-carboxaldehyde (3-Formylindole), also known as 3-formylindole or 3-indolealdehyde, belongs to the class of organic compounds known as indoles. Indole...
T4707 3-Hydroxyanthranilic acid 548-93-6 99.98%
3-Hydroxyanthranilic acid
3-Hydroxyanthranilic acid (3-HYDROXY-2-AMINOBENZOIC ACID), also known as 2-amino-3-hydroxy-benzoate or 3-ohaa, belongs to the class of organic compounds known as...
1-Aminopropan-2-ol
T66935
1-Aminopropan-2-ol is involved in the metabolism of threonine in Bacillus subtilis strains and can be used as a nitrogen source on fungal media.
Orotidine
TQ0148
Orotidine (Uridin-6-carboxylic acid) is a nucleoside found in bacteria, fungi, and plants. In humans, orotidine occurs as its 5'-phosphate (orotidylic acid).
D-Gluconic acid
T10934
D-Gluconic acid (D-Gluco-hexonic acid) is a carboxylic acid that has antiseptic and chelating properties through oxidation.
4-Hydroxyestrone
T9454
4-Hydroxyestrone, an endogenous estrogen metabolite, can strongly protect neuronal cells against oxidative damage.
Isoproterenol
T21411
Isoproterenol (Norisodrine) is a non-selective and orally active β-adrenoceptor agonist.Isoproterenol is a potent peripheral vasodilator and bronchodilator.Isopr...
Zymostenol
T35321
Zymostenol (5a-Cholest-8-en-3b-ol) is a RORγ agonist with an EC50 of 1 μM.Zymostenol is a late stage precursor of cholesterol biosynthesis.
D-(-)-Lactic acid
T10943
D-(-)-Lactic acid is a normal intermediate in sugar fermentation (oxidation, metabolism). It is identified as a competitive inhibitor of ProDH (proline dehydroge...
Nε,Nε,Nε-Trimethyllysine chloride
T5066
Nε,Nε,Nε-Trimethyllysine chloride (Lys(Me)3-OH Chloride) is a methylated derivative of the amino acid lysine. It is a component of histone proteins, a precursor ...
Prostaglandin D2
T13831
Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals,and is a potent endogenous sleep promoting substances.
Tetrahydrobiopterin
T17056
Tetrahydrobiopterin (BH4) is a cofactor for aromatic amino acid hydroxylases and an essential cofactor for nitric oxide synthase (NOS), which is used in the stud...
4-Ethylbenzaldehyde
T67670
4-Ethylbenzaldehyde is a RIFM flavor present in naturally fermented tilapia sausage and soybean plants.4-Ethylbenzaldehyde shows nematicidal activity at 250 g/ml...
C20 Ceramide
T40849
C20 Ceramide (N-Arachidoyl-D-sphingosine) is a 20:0 ceramide found in the brain that crosses the blood-brain barrier to activate microglia and induce depressive-...
3-Methoxytyramine
T8269
3-Methoxytyramine, an extracellular metabolite of 3-hydroxytyramine/dopamine, is a neuromodulator.
Succinyl-Coenzyme A sodium salt
T37323
Succinyl-Coenzyme A sodium salt(Succinyl-CoA sodium salt) participates in the citric acid cycle, where it is converted to succinic acid.Succinyl-Coenzyme A (sodi...
DL-Malic acid
TN6699
DL-Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid found in fruits such as apples and pears. It plays a role in many sour or acidic foods.
L-DOPA
T0848
L-DOPA (Levodopa) is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxyl...
Flavone
T2876
Flavone (2-Phenyl-4-chromone) have effects on CYP (P450) activity which are enzymes that metabolize most drugs in the body.
4-Methylbiphenyl
T8783
4-Methylbiphenyl (4-Phenyltoluene) is a human endogenous metabolite.
Indole-3-carboxaldehyde
T8105
1H-Indole-3-carboxaldehyde (3-Formylindole), also known as 3-formylindole or 3-indolealdehyde, belongs to the class of organic compounds known as indoles. Indole...
3-Hydroxyanthranilic acid
T4707
3-Hydroxyanthranilic acid (3-HYDROXY-2-AMINOBENZOIC ACID), also known as 2-amino-3-hydroxy-benzoate or 3-ohaa, belongs to the class of organic compounds known as...
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TargetMol