TN5100 |
Taspine
|
602-07-3
|
98%
|
|
Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of H...
|
TN3397 |
Alpinumisoflavone
|
34086-50-5
|
98%
|
|
Alpinumisoflavone has atheroprotective effects, may result from their ability to upregulate mechanisms promoting HDL-cholesterol and bile acid formation, it is e...
|
T12409 |
PERK-IN-2
|
1337531-83-5
|
98%
|
|
PERK-IN-2 is a potent inhibitor of PERK(IC50 of 0.2 nM).
|
TN1793 |
Isorhamnetin 3-O-galactoside
|
6743-92-6
|
98%
|
|
Isorhamnetin 3-O-galactoside shows antioxidant, anti-inflammatory, neuroprotective,and barrier protective activities, it could be used as a candidate therapeutic...
|
TN4489 |
Manassantin A
|
88497-87-4
|
98%
|
|
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effec...
|
TN3539 |
Broussonin A
|
73731-87-0
|
98%
|
|
Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin A shows estrogenic activity with ligand-binding activity of estrogen receptor, tra...
|
TN3839 |
Desoxo-narchinol A
|
53859-06-6
|
98%
|
|
Desoxo-narchinol A exhibits protective effects against LPS-induced endotoxin shock and inflammation through p38 deactivation, it shows inhibitory activity agains...
|
TN2995 |
4,10-Aromadendranediol
|
70051-38-6
|
98%
|
|
4,10-Aromadendranediol exhibits neurite outgrowth-inducing activity in neurons via activation of the ERK signaling pathway, which may be beneficial to the treatm...
|
TN3144 |
6,4'-Dihydroxy-7-methoxyflavanone
|
189689-32-5
|
98%
|
|
6,4'-Dihydroxy-7-methoxyflavanone is a biologically active compound isolated from the heartwood of Dalbergia odorifera T. Chen (Leguminosae) with antioxidant, an...
|
TN3152 |
6-Acetonyldihydrochelerythrine
|
22864-92-2
|
98%
|
|
6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therape...
|
TN4490 |
Manassantin B
|
88497-88-5
|
98%
|
|
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-κB. It also possesses anti-EBV ...
|
T16998 |
Tauroursodeoxycholate dihydrate
|
117609-50-4
|
98%
|
|
Tauroursodeoxycholate dihydrate is an endoplasmic reticulum stress inhibitor. Tauroursodeoxycholate also inhibits ERK. Tauroursodeoxycholate significantly decrea...
|
TN4213 |
Hirsutenone
|
41137-87-5
|
98%
|
|
Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid pero...
|
TN3931 |
Ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid
|
57719-81-0
|
98%
|
|
Ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid has anti-cancer activity, it induces apoptosis of human malignant cancer cells, it also inhibits hepatocellular ...
|
T13680 |
Enniatin B1
|
19914-20-6
|
98%
|
|
Enniatin B1, a Fusarium mycotoxin, crosses the blood-brain barrier, decreases the activation of ERK (p44/p42), and inhibits moderately TNF-α-induced NF-κB activa...
|
T12410 |
PERK-IN-3
|
1337532-08-7
|
98%
|
|
PERK-IN-3 is a potent inhibitor of PERK(IC50 of 7.4 nM).
|
T23337 |
SCH772984 HCl
|
T23337
|
98%
|
|
SCH772984 HCl is a selective inhibitor of ERK1/2 that displays behaviors of both type I and type II kinase inhibitors, with IC50s of 4 and 1 nM, respectively. SC...
|
T36067 |
Bongkrekic acid
|
11076-19-0
|
98%
|
|
Bongkrekic acid (Bongkrekic Acid (ammonium salt)) is a mitochondrial toxin secreted by Burkholderia gladioli that inhibits adenine nucleotide translocase (ANT).B...
|
TN5387 |
Grasshopper ketone
|
41703-38-2
|
98%
|
|
Grasshopper ketone, isolated from the brown alga Sargassum, is a potent inhibitor of LPS-induced NO production in RAW 264.7 cells and induces anti-inflammatory e...
|
TN3003 |
4-(3,4-Dimethoxyphenyl)-3-buten-1-ol
|
69768-97-4
|
98%
|
|
(E)-4-(3,4-dimethoxyphenyl)but-3-en-1-ol may promote melanin synthesis via USF1 dependent fashion and could be used as a clinical therapeutic agent against hypop...
|