Drug Metabolite

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom oxygenations, reductions, and dehydrogenations, heteroatom dealkylations, hydroxylations, can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No.	Product name	CAS No.	Purity
T38961L	DP-1 hydrochloride	1472616-35-5	99.29%
T38961L	DP-1 hydrochloride is a degradation product of SDC-TRAP-0063, a fragment of Ganetespib, a heat shock protein 90 (HSP90) inhibitor with antitumor activity.
T16338	Norgestimate metabolite Norelgestromin	53016-31-2	99.25%
T16338	Norgestimate metabolite Norelgestromin (17-Deacylnorgestimate) is one of the active metabolites of norgestimate.It is a steroidal progestin used in contraceptive...
T13539	Allopurinol riboside	16220-07-8	99.21%
T13539	Allopurinol riboside is a metabolite of allopurinol with potency against parasites. Allopurinol riboside competitively inhibits the action of purine nucleoside p...
T8217	Enzalutamide carboxylic acid	1242137-15-0	99.17%
T8217	Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) .
T6293	Mycophenolate Mofetil	128794-94-5	99.11%
T6293	Mycophenolate Mofetil (TM-MMF), an immunosuppressive agent, is the 2-morpholinoethyl ester of mycophenolic acid (MPA), and an inhibitor of inosine monophosphate ...
T35716	N-desmethyl Olanzapine	161696-76-0	99.1%
T35716	N-desmethyl Olanzapine is a metabolite of the atypical antipsychotic compound Olanzapinec, which is formed through the oxidative metabolism of olanzapine by the ...
T6619	Desmethyl Erlotinib hydrochloride	183320-51-6	99.03%
T6619	Desmethyl Erlotinib hydrochloride (OSI 420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM...
T4710	3-Methoxytyramine hydrochloride	1477-68-5	98.99%
T4710	3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride) is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (T...
T10138	4-Desmethoxy Omeprazole	110374-16-8	98.96%
T10138	4-Desmethoxy Omeprazole is the active metabolite of Omeprazole. Omeprazole is a proton pump inhibitor (PPI). Omeprazole shows competitive inhibition of CYP2C19 a...
T2687	Omeprazole sulfide	73590-85-9	98.77%
T2687	Omeprazole sulfide (Ufiprazole), a metabolite of Omeprazole, functions as a proton pump inhibitor.
T12005	Meta-Fexofenadine	479035-75-1	98.76%
T12005	meta-Fexofenadine (meta-MDL-16455) is an isomer of Fexofenadine.
T6328	Desmethyl Erlotinib	183321-86-0	98.62%
T6328	Desmethyl Erlotinib (CP-473420) is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM).
T11641	N-Desmethyl imatinib	404844-02-6	98.60%
T11641	N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.
T0050	Ampyrone	83-07-8	98.57%
T0050	Ampyrone (4-Aminoantipyrine) is a reagent for glucose determination in the presence of peroxidase and phenol.
T5158	N-Desmethylclozapine	6104-71-8	98.45%
T5158	N-Desmethylclozapine (Desmethylclozapine) is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 re...
T8175	DL-Laudanosine	1699-51-0	98.45%
T8175	DL-Laudanosine (Laudanosine) is a recognized metabolite of atracurium and cisatracurium.
T5186	Oseltamivir acid	187227-45-8	98.29%
T5186	Oseltamivir acid (GS4071) is a potent influenza virus neuraminidase inhibitor and the prodrug of GS4071.
T4000	(±)-Equol	94105-90-5	98.28%
T4000	(±)-Equol ((R,S)-Equol) is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora. The es...
TN1352	N-(3-Methoxybenzyl-(9z,12z)-octadecadienamide	883715-22-8	98.22%
TN1352	N-(3-Methoxybenzyl-(9z,12z)-octadecadienamide ((9Z,12Z)-N-(3-Methoxybenzyl)octadeca-9,12-dienamide) is a Macamide impurity that may be used in the study of metab...
T10157	Regorafénib N-oxyde (M2)	835621-11-9	98.03%
T10157	Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, RET, Kit, and Raf-1 (IC50s: 13/4.2...