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Dopamine Receptor

Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate different effectors through not only G-protein coupling, but also signaling through different protein (dopamine receptor-interacting proteins) interactions.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T0445 Promethazine 60-87-7 99.11%
Promethazine
Promethazine (Proazamine) is an analogue of anti-glaucoma prostaglandin (PG) .
T34616 Seridopidine 883631-51-4 99.11%
Seridopidine
Seridopidine (ACR343) is a modulator of dopaminergic activity that is used as an oral therapy for schizophrenia, Parkinson's disease, and Tourette's syndrome.
T12489 Pimethixene 314-03-4 99.1%
Pimethixene
Pimethixene (Calmixen) is a highly potent 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors antagonist...
T2226 Pergolide mesylate 66104-23-2 99.09%
Pergolide mesylate
Pergolide mesylate salt(LY127809) is a long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some...
T4369 SCH-23390 hydrochloride 125941-87-9 99.07%
SCH-23390 hydrochloride
SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).
T17072 Thiethylperazine dimaleate 1179-69-7 99.07%
Thiethylperazine dimaleate
Thiethylperazine dimaleate (Thiethylperazine maleate) is an antagonist of the D2 receptor and H1 receptor. Thiethylperazine dimaleate is an activator of ABCC1 an...
T21855 AMI-193 510-74-7 99.04%
AMI-193
AMI-193 (Spiramide) is an effective and selective antagonist of 5-HT2 and D2 receptor with Kis of 2, 3, 50, 2530, and 4300 nM for 5-HT2, D2 Receptor, 5-HT1A, D1 ...
T22508 3-CPMT 14008-79-8 99.03%
3-CPMT
3-CPMT (FC-1) is a dopamine uptake inhibitor and a potent long-acting antihistaminic agent.
T8389 Trifluoperazine 117-89-5 99.03%
Trifluoperazine
Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.
T0716 Molindone hydrochloride 15622-65-8 99%
Molindone hydrochloride
Molindone hydrochloride (EN-1733A) is an indole derivative effective in schizophrenia and other psychoses by blocking the effects of dopamine in the brain.
T9409 Mesdopetam hemitartrate 2562346-14-7 98.96%
Mesdopetam hemitartrate
Mesdopetam hemitartrate (IRL790 hemitartrate) is an antagonist of dopamine D3 receptor (Ki=90 nM; IC50=9.8 μM for human recombinant D3 receptor). It has psychomo...
T12405 Pentiapine 81382-51-6 98.93%
Pentiapine
Pentiapine (CGS 10746) is a novel inhibitor of dopamine release.
T3526 Dasotraline hydrochloride 675126-08-6 98.92%
Dasotraline hydrochloride
Dasotraline hydrochloride (SEP-225289 hydrochloride) (SEP-225289 hydrochloride) is a triple reuptake inhibitor that inhibits dopamine, norepinephrine, and seroto...
T28809 SLV-310 264869-71-8 98.91%
SLV-310
SLV-310 is a potent dopamine D2 receptor antagonist and 5-HT reuptake receptor inhibitor used in the study of neurological disorders such as bipolar disorder and...
T15686 L-741626 81226-60-0 98.9%
L-741626
L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3 an...
T7728 ACEPROMAZINE MALEATE 3598-37-6 98.87%
ACEPROMAZINE MALEATE
ACEPROMAZINE MALEATE is a dopamine receptor antagonist
T4576 Perospirone 150915-41-6 98.86%
Perospirone
Perospirone (Lullan) is an antagonist of serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agon...
T1292 Tiapride hydrochloride 51012-33-0 98.86%
Tiapride hydrochloride
Tiapride is a selective blocker of D2/3 dopamine receptors in the brain. It is used in the therapy of various psychiatric and neurological disorders containing d...
T9237 Rotigotine 92206-54-7 98.84%
Rotigotine
Rotigotine (1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-) is an antiparkinson agent and dopamine receptor agonist.
T5047 PD-168077 maleate 630117-19-0 98.82%
PD-168077 maleate
PD-168077 maleate is a selective agonist of dopamine D4 receptor(Ki : 9 nM)
Promethazine
T0445
Promethazine (Proazamine) is an analogue of anti-glaucoma prostaglandin (PG) .
Seridopidine
T34616
Seridopidine (ACR343) is a modulator of dopaminergic activity that is used as an oral therapy for schizophrenia, Parkinson's disease, and Tourette's syndrome.
Pimethixene
T12489
Pimethixene (Calmixen) is a highly potent 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors antagonist...
Pergolide mesylate
T2226
Pergolide mesylate salt(LY127809) is a long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some...
SCH-23390 hydrochloride
T4369
SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).
Thiethylperazine dimaleate
T17072
Thiethylperazine dimaleate (Thiethylperazine maleate) is an antagonist of the D2 receptor and H1 receptor. Thiethylperazine dimaleate is an activator of ABCC1 an...
AMI-193
T21855
AMI-193 (Spiramide) is an effective and selective antagonist of 5-HT2 and D2 receptor with Kis of 2, 3, 50, 2530, and 4300 nM for 5-HT2, D2 Receptor, 5-HT1A, D1 ...
3-CPMT
T22508
3-CPMT (FC-1) is a dopamine uptake inhibitor and a potent long-acting antihistaminic agent.
Trifluoperazine
T8389
Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.
Molindone hydrochloride
T0716
Molindone hydrochloride (EN-1733A) is an indole derivative effective in schizophrenia and other psychoses by blocking the effects of dopamine in the brain.
Mesdopetam hemitartrate
T9409
Mesdopetam hemitartrate (IRL790 hemitartrate) is an antagonist of dopamine D3 receptor (Ki=90 nM; IC50=9.8 μM for human recombinant D3 receptor). It has psychomo...
Pentiapine
T12405
Pentiapine (CGS 10746) is a novel inhibitor of dopamine release.
Dasotraline hydrochloride
T3526
Dasotraline hydrochloride (SEP-225289 hydrochloride) (SEP-225289 hydrochloride) is a triple reuptake inhibitor that inhibits dopamine, norepinephrine, and seroto...
SLV-310
T28809
SLV-310 is a potent dopamine D2 receptor antagonist and 5-HT reuptake receptor inhibitor used in the study of neurological disorders such as bipolar disorder and...
L-741626
T15686
L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3 an...
ACEPROMAZINE MALEATE
T7728
ACEPROMAZINE MALEATE is a dopamine receptor antagonist
Perospirone
T4576
Perospirone (Lullan) is an antagonist of serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agon...
Tiapride hydrochloride
T1292
Tiapride is a selective blocker of D2/3 dopamine receptors in the brain. It is used in the therapy of various psychiatric and neurological disorders containing d...
Rotigotine
T9237
Rotigotine (1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-) is an antiparkinson agent and dopamine receptor agonist.
PD-168077 maleate
T5047
PD-168077 maleate is a selective agonist of dopamine D4 receptor(Ki : 9 nM)
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TargetMol