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Dopamine Receptor

Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate different effectors through not only G-protein coupling, but also signaling through different protein (dopamine receptor-interacting proteins) interactions.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T13245 UCSF924 1434515-70-4 98%
UCSF924
UCSF924 is a potent and specific agonist of dopamine D4 receptor (DRD4) partial (EC50: 4.2 nM, Ki: 3 nM).
T12288 Odapipam 131796-63-9 98%
Odapipam
Odapipam is a selective and high affinity antagonist of benzazepine dopamine D1 receptor (Kd of 0.18 nM).
T1476L Pramipexole dihydrochloride 104632-25-9 98%
Pramipexole dihydrochloride
Pramipexole dihydrochloride could be used to treat Parkinson disease.
T22921 LE 300 274694-98-3 98%
LE 300
dopamine D1 receptor antagonist
T10611 Brexpiprazole S-oxide D8 2748605-29-8 98%
Brexpiprazole S-oxide D8
Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium labeled Brexpiprazole S-oxide. Brexpiprazole S-oxide is a main metabolite of Brexpiprazole. Brexpiprazole is...
T21360 Asenapine 65576-45-6 98%
Asenapine
Asenapine (Org 5222) is a 5-HT receptor, adrenergic receptor, dopamine receptor, and histamine receptor antagonist with antipsychotic effects that is used to tre...
TQ0175 Dexpramipexole 104632-28-2 98%
Dexpramipexole
Dexpramipexole (KNS-760704, R-(+)-Pramipexole) is a neuroprotective agent and weak non-ergoline dopamine agonist.
TQ0140 Sumanirole maleate 179386-44-8 98%
Sumanirole maleate
Sumanirole maleate (U-95666E) is a highly selective full agonist of the D2 receptor (ED50: 46 nM).
T7341 Diclofensine 67165-56-4 98%
Diclofensine
Diclofensine (Ro 8-4650) inhibits the uptake of serotonin, noradrenaline and dopamine.
T9540 Phenelzine 51-71-8 98%
Phenelzine
Phenelzine is an antidepressant and mania drug, which is a monoamine oxidase inhibitor. Its antidepressant effect is similar to that of niacinamide. It can reduc...
T11799L L-745870 158985-00-3 98%
L-745870
L-745870 is a high-affinity and selective human dopamine D4 receptor antagonist (Ki: 0.43 nM). L-745870 has excellent brain penetration. It considerably weaker D...
T12476 Pimozide-d4 1803193-57-8 98%
Pimozide-d4
Pimozide D4 is a deuterium labeled Pimozide.
T13463L Dihydrexidine 123039-93-0 98%
Dihydrexidine
Dihydrexidine is a full efficacy D1-like dopamine receptor (D1/D5) agonist (IC50: 10 nM for D1 receptor). It also shows potent antiparkinsonian activity.
T13898 SPD-473 citrate 161190-26-7 98%
SPD-473 citrate
SPD-473 citrate is an inhibitior of serotonin/dopamine/norepinephrine reuptake.
T10908 CY 208-243 100999-26-6 98%
CY 208-243
CY 208-243 is a selective dopamine D1 receptor agonist with anti-Parkinson disease activity.
T12865 SCH-23390 maleate 87134-87-0 98%
SCH-23390 maleate
SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM, r...
T13652 Dicarbine 17411-19-7 98%
Dicarbine
Double carbene can be used for the study of schizophrenia and alcoholism. It can block dopamine receptors in various parts of the brain and prevent the reduction...
T68023 Tolnapersine 70312-00-4 98%
Tolnapersine
Tolnapersine is a mixed dopamine agonist and alpha-adrenoceptor antagonist.
T10681 Cariprazine D6 1308278-67-2 98%
Cariprazine D6
Cariprazine D6 (RGH-188 D6) is a deuterium-labeled Cariprazine. Cariprazine is an antipsychotic agent (D3 receptors, Ki: 0.085 nM; D2 receptors, Ki: 0.49 nM).
TN1424 Bacopaside X 94443-88-6 98%
Bacopaside X
Bacopaside X (9.06 μM) showed binding affinity towards the D1 receptor.
UCSF924
T13245
UCSF924 is a potent and specific agonist of dopamine D4 receptor (DRD4) partial (EC50: 4.2 nM, Ki: 3 nM).
Odapipam
T12288
Odapipam is a selective and high affinity antagonist of benzazepine dopamine D1 receptor (Kd of 0.18 nM).
Pramipexole dihydrochloride
T1476L
Pramipexole dihydrochloride could be used to treat Parkinson disease.
LE 300
T22921
dopamine D1 receptor antagonist
Brexpiprazole S-oxide D8
T10611
Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium labeled Brexpiprazole S-oxide. Brexpiprazole S-oxide is a main metabolite of Brexpiprazole. Brexpiprazole is...
Asenapine
T21360
Asenapine (Org 5222) is a 5-HT receptor, adrenergic receptor, dopamine receptor, and histamine receptor antagonist with antipsychotic effects that is used to tre...
Dexpramipexole
TQ0175
Dexpramipexole (KNS-760704, R-(+)-Pramipexole) is a neuroprotective agent and weak non-ergoline dopamine agonist.
Sumanirole maleate
TQ0140
Sumanirole maleate (U-95666E) is a highly selective full agonist of the D2 receptor (ED50: 46 nM).
Diclofensine
T7341
Diclofensine (Ro 8-4650) inhibits the uptake of serotonin, noradrenaline and dopamine.
Phenelzine
T9540
Phenelzine is an antidepressant and mania drug, which is a monoamine oxidase inhibitor. Its antidepressant effect is similar to that of niacinamide. It can reduc...
L-745870
T11799L
L-745870 is a high-affinity and selective human dopamine D4 receptor antagonist (Ki: 0.43 nM). L-745870 has excellent brain penetration. It considerably weaker D...
Pimozide-d4
T12476
Pimozide D4 is a deuterium labeled Pimozide.
Dihydrexidine
T13463L
Dihydrexidine is a full efficacy D1-like dopamine receptor (D1/D5) agonist (IC50: 10 nM for D1 receptor). It also shows potent antiparkinsonian activity.
SPD-473 citrate
T13898
SPD-473 citrate is an inhibitior of serotonin/dopamine/norepinephrine reuptake.
CY 208-243
T10908
CY 208-243 is a selective dopamine D1 receptor agonist with anti-Parkinson disease activity.
SCH-23390 maleate
T12865
SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM, r...
Dicarbine
T13652
Double carbene can be used for the study of schizophrenia and alcoholism. It can block dopamine receptors in various parts of the brain and prevent the reduction...
Tolnapersine
T68023
Tolnapersine is a mixed dopamine agonist and alpha-adrenoceptor antagonist.
Cariprazine D6
T10681
Cariprazine D6 (RGH-188 D6) is a deuterium-labeled Cariprazine. Cariprazine is an antipsychotic agent (D3 receptors, Ki: 0.085 nM; D2 receptors, Ki: 0.49 nM).
Bacopaside X
TN1424
Bacopaside X (9.06 μM) showed binding affinity towards the D1 receptor.
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TargetMol