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Dopamine Receptor

Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate different effectors through not only G-protein coupling, but also signaling through different protein (dopamine receptor-interacting proteins) interactions.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T61807 5-HT6/7 antagonist 1 131999-28-5 98.78%
5-HT6/7 antagonist 1
5-HT6/7 antagonist 1 is a dual 5-HT6/7/2A and D2 receptor antagonist for the study of dementia and Alzheimer's disease.
TN1217 2'-O-Methylisoliquiritigenin 51828-10-5 98.75%
2'-O-Methylisoliquiritigenin
2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR.2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-re...
T3431 Pardoprunox hydrochloride 269718-83-4 98.73%
Pardoprunox hydrochloride
Pardoprunox hydrochloride (SLV-308 hydrochloride) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) an...
T1322 Bendazol 621-72-7 98.7%
Bendazol
Bendazol (Dibazol) is always used as the drug for hypertension and cerebral Angiospasm.
T14490 Talipexole dihydrochloride 36085-73-1 98.64%
Talipexole dihydrochloride
Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and intestinal...
T10213 A-437203 220519-06-2 98.62%
A-437203
A-437203 (Lu201640) is A kind of based on 1 h - pyrimidin - 2 - one sca ff old, selective, new powerful d3 receptor antagonist, on D2, d3, and D4 receptor, Ki val...
T12861 SB-277011 215803-78-4 98.61%
SB-277011
SB-277011 (SB-277011A) is a specific antagonist of the dopamine D3 receptor with pKi values of 8.0, 6.0, 5.0, and <5.2 for D3 receptor, D2 receptor, 5-HT1D, and ...
T7635 Raclopride 84225-95-6 98.6%
Raclopride
Raclopride is a selective antagonist of dopamine D2/D3 receptor.
TQ0084 Lumateperone Tosylate 1187020-80-9 98.57%
lumateperone Tosylate
lumateperone Tosylate (ITI-007) is a 5-HT2A receptor antagonist (Ki: 0.54 nM), a SERT blocker (Ki: 61 nM), a partial agonist of presynaptic D2 receptors and an a...
T1476 Pramipexole 104632-26-0 98.54%
Pramipexole
Pramipexole (SND 919) is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of tra...
T11079 NMI 8739 129024-87-9 98.51%
NMI 8739
NMI 8739 (n-docosahexaenoyl dopamine) is an agonist of D2 autoreceptor. NMI 8739 reduces NO production and elicits concentration-dependent suppression of CCL-20,...
T31602 Ecopipam 112108-01-7 98.5%
Ecopipam
Ecopipam (UNII-0X748O646K) is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam ...
T7070 Nomifensine maleate 32795-47-4 98.46%
Nomifensine maleate
Nomifensine maleate (Nomifensine (maleate)) is a selective inhibitor of dopamine uptake. Nomifensine maleate is used in adult attention deficit disorder.
T60835 SKF83959 80751-85-5 98.45%
SKF83959
SKF83959, a benzazepine analog, is a selective and potent partial agonist of the dopamine D1 receptor with Ki values of 1.18, 7.56, 920, and 399 nM for rat D1, D...
T5158 N-Desmethylclozapine 6104-71-8 98.45%
N-Desmethylclozapine
N-Desmethylclozapine (Desmethylclozapine) is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 re...
T60107 N-0500 HCl 100935-99-7 98.42%
N-0500 HCl
N-0500 HCl ((-)-Propyl-9-hydroxynaphthoxazine Hydrochloride) is a very potent centrally acting DA receptor agonist. N-0500 HCl is a potent displacer of the speci...
T0990 Droperidol 548-73-2 98.38%
Droperidol
Droperidol (Dehydrobenzperidol) is a Dopamine-2 Receptor Antagonist. The mechanism of action of droperidol is as a Dopamine D2 Antagonist.
T24444 Medifoxamine 32359-34-5 98.35%
Medifoxamine
Medifoxamine (LG 152) is a selective non-monoamine oxidase inhibitor that exhibits antidepressant activity through inhibition of 5 HT reuptake.Medifoxamine prefe...
T71707L Romergoline 2HCl 98.33%
Romergoline 2HCl
Romergoline 2HCl is a D1 agonist and D2 antagonist used in the study of Parkinson's disease.
T24613 PF-00217830 846032-02-8 98.30%
PF-00217830
PF-00217830 is a serotonin 1A receptor agonist, dopamine D2 receptor agonist, and serotonin 2A receptor antagonist.PF-00217830 may be used in the study of schizo...
5-HT6/7 antagonist 1
T61807
5-HT6/7 antagonist 1 is a dual 5-HT6/7/2A and D2 receptor antagonist for the study of dementia and Alzheimer's disease.
2'-O-Methylisoliquiritigenin
TN1217
2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR.2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-re...
Pardoprunox hydrochloride
T3431
Pardoprunox hydrochloride (SLV-308 hydrochloride) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) an...
Bendazol
T1322
Bendazol (Dibazol) is always used as the drug for hypertension and cerebral Angiospasm.
Talipexole dihydrochloride
T14490
Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and intestinal...
A-437203
T10213
A-437203 (Lu201640) is A kind of based on 1 h - pyrimidin - 2 - one sca ff old, selective, new powerful d3 receptor antagonist, on D2, d3, and D4 receptor, Ki val...
SB-277011
T12861
SB-277011 (SB-277011A) is a specific antagonist of the dopamine D3 receptor with pKi values of 8.0, 6.0, 5.0, and <5.2 for D3 receptor, D2 receptor, 5-HT1D, and ...
Raclopride
T7635
Raclopride is a selective antagonist of dopamine D2/D3 receptor.
lumateperone Tosylate
TQ0084
lumateperone Tosylate (ITI-007) is a 5-HT2A receptor antagonist (Ki: 0.54 nM), a SERT blocker (Ki: 61 nM), a partial agonist of presynaptic D2 receptors and an a...
Pramipexole
T1476
Pramipexole (SND 919) is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of tra...
NMI 8739
T11079
NMI 8739 (n-docosahexaenoyl dopamine) is an agonist of D2 autoreceptor. NMI 8739 reduces NO production and elicits concentration-dependent suppression of CCL-20,...
Ecopipam
T31602
Ecopipam (UNII-0X748O646K) is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam ...
Nomifensine maleate
T7070
Nomifensine maleate (Nomifensine (maleate)) is a selective inhibitor of dopamine uptake. Nomifensine maleate is used in adult attention deficit disorder.
SKF83959
T60835
SKF83959, a benzazepine analog, is a selective and potent partial agonist of the dopamine D1 receptor with Ki values of 1.18, 7.56, 920, and 399 nM for rat D1, D...
N-Desmethylclozapine
T5158
N-Desmethylclozapine (Desmethylclozapine) is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 re...
N-0500 HCl
T60107
N-0500 HCl ((-)-Propyl-9-hydroxynaphthoxazine Hydrochloride) is a very potent centrally acting DA receptor agonist. N-0500 HCl is a potent displacer of the speci...
Droperidol
T0990
Droperidol (Dehydrobenzperidol) is a Dopamine-2 Receptor Antagonist. The mechanism of action of droperidol is as a Dopamine D2 Antagonist.
Medifoxamine
T24444
Medifoxamine (LG 152) is a selective non-monoamine oxidase inhibitor that exhibits antidepressant activity through inhibition of 5 HT reuptake.Medifoxamine prefe...
Romergoline 2HCl
T71707L
Romergoline 2HCl is a D1 agonist and D2 antagonist used in the study of Parkinson's disease.
PF-00217830
T24613
PF-00217830 is a serotonin 1A receptor agonist, dopamine D2 receptor agonist, and serotonin 2A receptor antagonist.PF-00217830 may be used in the study of schizo...
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TargetMol