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Dopamine Receptor

Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate different effectors through not only G-protein coupling, but also signaling through different protein (dopamine receptor-interacting proteins) interactions.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T4494 CLOZAPINE N-OXIDE 34233-69-7 98.65%
CLOZAPINE N-OXIDE
Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration [1]. It is produ...
T14490 Talipexole dihydrochloride 36085-73-1 98.64%
Talipexole dihydrochloride
Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and intestinal...
T10213 A-437203 220519-06-2 98.62%
A-437203
A-437203 (Lu201640) is A kind of based on 1 h - pyrimidin - 2 - one sca ff old, selective, new powerful d3 receptor antagonist, on D2, d3, and D4 receptor, Ki val...
T12861 SB-277011 215803-78-4 98.61%
SB-277011
SB-277011 (SB-277011A) is a specific antagonist of the dopamine D3 receptor with pKi values of 8.0, 6.0, 5.0, and <5.2 for D3 receptor, D2 receptor, 5-HT1D, and ...
T7635 Raclopride 84225-95-6 98.6%
Raclopride
Raclopride is a selective antagonist of dopamine D2/D3 receptor.
T11079 NMI 8739 129024-87-9 98.51%
NMI 8739
NMI 8739 (n-docosahexaenoyl dopamine) is an agonist of D2 autoreceptor. NMI 8739 reduces NO production and elicits concentration-dependent suppression of CCL-20,...
T31602 Ecopipam 112108-01-7 98.5%
Ecopipam
Ecopipam (UNII-0X748O646K) is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam ...
T60835 SKF83959 80751-85-5 98.45%
SKF83959
SKF83959, a benzazepine analog, is a selective and potent partial agonist of the dopamine D1 receptor with Ki values of 1.18, 7.56, 920, and 399 nM for rat D1, D...
T60107 N-0500 HCl 100935-99-7 98.42%
N-0500 HCl
N-0500 HCl ((-)-Propyl-9-hydroxynaphthoxazine Hydrochloride) is a very potent centrally acting DA receptor agonist. N-0500 HCl is a potent displacer of the speci...
T0990 Droperidol 548-73-2 98.38%
Droperidol
Droperidol (Dehydrobenzperidol) is a Dopamine-2 Receptor Antagonist. The mechanism of action of droperidol is as a Dopamine D2 Antagonist.
T24444 Medifoxamine 32359-34-5 98.35%
Medifoxamine
Medifoxamine (LG 152) is a selective non-monoamine oxidase inhibitor that exhibits antidepressant activity through inhibition of 5 HT reuptake.Medifoxamine prefe...
T24613 PF-00217830 846032-02-8 98.30%
PF-00217830
PF-00217830 is a serotonin 1A receptor agonist, dopamine D2 receptor agonist, and serotonin 2A receptor antagonist.PF-00217830 may be used in the study of schizo...
TQ0176 (-)-Isocorypalmine 483-34-1 98.18%
(-)-Isocorypalmine
(-)-Isocorypalmine ((S)-Tetrahydrocolumbamine), a natural product isolated from Corydalis chaerophylla, has significant antifungal activity.
T78825 D4R agonist-1 2826198-44-9 98.16%
D4R agonist-1
D4R agonist-1 is a selective and potent D4R partial agonist (Ki:2.2 nM).D4R agonist-1 can be used to study neurological diseases.
T26375 (S)-Amisulpride 71675-92-8 98.16%
(S)-Amisulpride
(S)-Amisulpride ((S) Amisulpride) (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist. (S)-Amisulpride is an antagonist at the 5-HT7 receptor with a K...
T1233 Oxolinic acid 14698-29-4 98.15%
Oxolinic acid
Oxolinic acid (Nidantin) is a synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.
T11722 JNJ-37822681 dihydrochloride 2108806-02-4 98.13%
JNJ-37822681 dihydrochloride
JNJ-37822681 has potential for the treatment of schizophrenia and bipolar disorder.JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dis...
T68023L Tolnapersine TFA T68023L 98.10%
Tolnapersine TFA
Tolnapersine TFA is a mixed dopamine agonist and alpha adrenergic receptor antagonist.
T21667 FAUC-365 474432-66-1 98.09%
FAUC-365
FAUC-365 is a D3 dopamine receptor agonist.
T2564 Cis-(Z)-Flupentixol dihydrochloride 51529-01-2 98.07%
cis-(Z)-Flupentixol dihydrochloride
cis-(Z)-Flupentixol dihydrochloride (Emergil) is a dopamine receptor antagonist.
CLOZAPINE N-OXIDE
T4494
Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration [1]. It is produ...
Talipexole dihydrochloride
T14490
Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and intestinal...
A-437203
T10213
A-437203 (Lu201640) is A kind of based on 1 h - pyrimidin - 2 - one sca ff old, selective, new powerful d3 receptor antagonist, on D2, d3, and D4 receptor, Ki val...
SB-277011
T12861
SB-277011 (SB-277011A) is a specific antagonist of the dopamine D3 receptor with pKi values of 8.0, 6.0, 5.0, and <5.2 for D3 receptor, D2 receptor, 5-HT1D, and ...
Raclopride
T7635
Raclopride is a selective antagonist of dopamine D2/D3 receptor.
NMI 8739
T11079
NMI 8739 (n-docosahexaenoyl dopamine) is an agonist of D2 autoreceptor. NMI 8739 reduces NO production and elicits concentration-dependent suppression of CCL-20,...
Ecopipam
T31602
Ecopipam (UNII-0X748O646K) is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam ...
SKF83959
T60835
SKF83959, a benzazepine analog, is a selective and potent partial agonist of the dopamine D1 receptor with Ki values of 1.18, 7.56, 920, and 399 nM for rat D1, D...
N-0500 HCl
T60107
N-0500 HCl ((-)-Propyl-9-hydroxynaphthoxazine Hydrochloride) is a very potent centrally acting DA receptor agonist. N-0500 HCl is a potent displacer of the speci...
Droperidol
T0990
Droperidol (Dehydrobenzperidol) is a Dopamine-2 Receptor Antagonist. The mechanism of action of droperidol is as a Dopamine D2 Antagonist.
Medifoxamine
T24444
Medifoxamine (LG 152) is a selective non-monoamine oxidase inhibitor that exhibits antidepressant activity through inhibition of 5 HT reuptake.Medifoxamine prefe...
PF-00217830
T24613
PF-00217830 is a serotonin 1A receptor agonist, dopamine D2 receptor agonist, and serotonin 2A receptor antagonist.PF-00217830 may be used in the study of schizo...
(-)-Isocorypalmine
TQ0176
(-)-Isocorypalmine ((S)-Tetrahydrocolumbamine), a natural product isolated from Corydalis chaerophylla, has significant antifungal activity.
D4R agonist-1
T78825
D4R agonist-1 is a selective and potent D4R partial agonist (Ki:2.2 nM).D4R agonist-1 can be used to study neurological diseases.
(S)-Amisulpride
T26375
(S)-Amisulpride ((S) Amisulpride) (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist. (S)-Amisulpride is an antagonist at the 5-HT7 receptor with a K...
Oxolinic acid
T1233
Oxolinic acid (Nidantin) is a synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.
JNJ-37822681 dihydrochloride
T11722
JNJ-37822681 has potential for the treatment of schizophrenia and bipolar disorder.JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dis...
Tolnapersine TFA
T68023L
Tolnapersine TFA is a mixed dopamine agonist and alpha adrenergic receptor antagonist.
FAUC-365
T21667
FAUC-365 is a D3 dopamine receptor agonist.
cis-(Z)-Flupentixol dihydrochloride
T2564
cis-(Z)-Flupentixol dihydrochloride (Emergil) is a dopamine receptor antagonist.
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TargetMol