T7732 |
Carbenoxolone
|
5697-56-3
|
99.52%
|
|
Carbenoxolone (Biogastrone) is an inhibitor of 11β-HSD and gap junction connexin channels. Carbenoxolone inhibits macrophage migration into atria and prevents th...
|
T63341 |
ALDH1A1-IN-2
|
2231081-18-6
|
99.48%
|
|
ALDH1A1-IN-2 is a potent aldehyde dehydrogenase 1a1 (aldh1a1) inhibitor with anticancer activity.ALDH1A1-IN-2 may be used in the study of breast cancer, inflamma...
|
T2637 |
ADH-1
|
229971-81-7
|
98.1%
|
|
ADH-1 (Exherin) is an N-cadherin antagonist, inhibits N-cadherin mediated cell adhesion with potential antineoplastic and antiangiogenic activities.
|
T64360 |
HDHODH-IN-8
|
2757405-31-3
|
98%
|
|
hDHODH-IN-8 is a potent inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 16 nM. hDHODH-IN-8 has potent antiproliferative activity and exc...
|
T14780 |
BRD9185
|
2057420-29-6
|
98%
|
|
BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.
|
T16269 |
Nanaomycin A
|
52934-83-5
|
98%
|
|
Nanaomycin A, a quinone antibiotics, reactivates silenced tumor suppressor genes in human cancer cells. Nanaomycin A is a selective inhibitor of DNMT3B (IC50 = 5...
|
T11611 |
IDH1 Inhibitor 2
|
2244895-42-7
|
98%
|
|
IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor via direct covalent modification of His315 (IC50: 110 nM).
|
T12663 |
(Rac)-BMS-816336
|
T12663
|
98%
|
|
(Rac)-BMS-816336 (Compound 6n) is a racemate of BMS-816336. (Rac)-BMS-816336 is a potent human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzym...
|
T11238 |
Etamicastat
|
760173-05-5
|
98%
|
|
Etamicastat can be used in the research of cardiovascular diseases. Etamicastat (BIA 5-453) is a potent and reversible dopamine-β-hydroxylase (DBH) inhibitor wit...
|
T14383 |
AZD8329
|
1048668-70-7
|
98%
|
|
AZD8329 is a selectable and potent inhibitor of human recombinant 11β-HSD1 and isolated human adipocyte 11ß-HSD1 and is an inhibitor of rat 11β-HSD1 (IC50 - 89nM...
|
T13054 |
T-3764518
|
1809151-56-1
|
98%
|
|
T-3764518 is a novel and potent inhibitor of stearoyl coenzyme A desaturase (SCD)(IC50 of 4.7 nM).
|
TN3364 |
Agrimonolide
|
21499-24-1
|
98%
|
|
Agrimonolide, a compound derived from isocoumarins and found mainly in the herb Agrimonia pilosa Ledeb, has significant biological activity. agrimonolide exerts ...
|
TN1298 |
6''-O-Acetylglycitin
|
134859-96-4
|
98%
|
|
6''-O-Acetylglycitin is a potential nutriceutical, it is also a potent LDH inhibitor.
|
T5S2195 |
Sibiricose A5
|
107912-97-0
|
99.99%
|
|
Sibiricose A5 is a lactate dehydrogenase inhibitor, it displays antidepressant-like, and antioxidant actions. Sibiricose A5 can protect PC12 cells damage induced...
|
T3019 |
Physcion
|
521-61-9
|
99.96%
|
|
Physcion (Physcione) (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate ...
|
T10160 |
11β-HSD1-IN-1
|
1203956-47-1
|
99.96%
|
|
11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.
|
T0010 |
6-Mercaptopurine
|
50-44-2
|
99.94%
|
|
6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting puri...
|
T2662 |
Alda-1
|
349438-38-6
|
99.93%
|
|
Alda-1 is an ALDH2 agonist, a cell-permeable activator of both the wild-type ALDH2*1 and the Asian E487K mutant ALDH2*2 forms of mitochondrial aldehyde dehydroge...
|
T0746 |
Orotic acid
|
65-86-1
|
99.93%
|
|
Orotic acid (Vitamin B13) is an intermediate product in pyrimidine metabolism.
|
T1165 |
Ethionamide
|
536-33-4
|
99.92%
|
|
Ethionamide (2-ethylthioisonicotinamide) is a nicotinamide derivative, with antibacterial activity, used to treat tuberculosis. Although the exact mechanism of a...
|