T1508 |
Decitabine
|
2353-33-5
|
99.17%
|
|
Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic a...
|
T24871 |
TFMB-(S)-2-HG
|
1445703-64-9
|
98.88%
|
|
TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase. Additionally, it significantly inhibits the EglN prolyl h...
|
T60322 |
Procainamide
|
51-06-9
|
98.86%
|
|
Procainamide (Novocainamide) is a specific and potent DNA methyltransferase 1 ( DNMT1 ) inhibitor. Procainamide is a Class 1A antiarrhythmic agent. Procainamide ...
|
T3089 |
6-Thioguanine
|
154-42-7
|
98.75%
|
|
6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
|
T7194 |
CM-272
|
1846570-31-7
|
98.21%
|
|
CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.
|
T16287 |
Neurodazine
|
937807-66-4
|
98.01%
|
|
Neurodazine is a neural inducer that promotes the differentiation of pluripotent cells into neuronal cells.Neurodazine promotes differentiation by activating Wnt...
|
T8967 |
SW155246
|
420092-79-1
|
97.79%
|
|
SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM). SW155246 induces re-expression of the tumor suppressor geneRASSF...
|
T11469 |
GSK-3484862
|
2170136-65-7
|
100%
|
|
GSK-3484862 is a non-covalent Dnmt1 inhibitor. It induces DNA hypomethylation to against cancer.
|
T0018 |
Procainamide hydrochloride
|
614-39-1
|
100%
|
|
Procainamide Hydrochloride (Procapan) is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analog ...
|
T2169 |
Zebularine
|
3690-10-6
|
100%
|
|
Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor. Acts as a transition state analog inhibitor of cytidine deaminase by binding to the active size as co...
|
T5198 |
Bobcat339
|
2280037-51-4
|
|
|
Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.
|
T9573 |
GSK3685032
|
2170137-61-6
|
98%
|
|
GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM). The inhibitory effect is time-independent and reversible. GSK3685032 induces loss of DN...
|