Cat. No. | Product name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T13568L | BCX 1470 hydrochloride | 98.76% |
|
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BCX 1470 hydrochloride is a potent serine protease inhibitor with anti-inflammatory activity that inhibits the ester hydrolysis and haemolytic activity of factor... | ||||
T64388 | 3-Phenoxybenzaldehyde | 39515-51-0 | 98.61% |
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3-Phenoxybenzaldehyde is a complement (classical pathway) inhibitor with IC50 of 1388μM. | ||||
T3638 | Leukadherin-1 | 344897-95-6 | 98.49% |
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Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte motility and transendot... | ||||
T9915 | Eculizumab | 219685-50-4 | 98.20% |
Eculizumab
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Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5 | ||||
T0945 | Cyclosporin A | 59865-13-3 | 98% |
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Cyclosporin A is a Calcineurin Inhibitor Immunosuppressant. The mechanism of action of cyclosporine is as a Calcineurin Inhibitor, and Cytochrome P450 3A4 Inhibi... | ||||
T38287 | C3a Receptor Agonist | 944997-60-8 | 97.5% |
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C3a Receptor Agonist (C3a receptor agonist 1) binds the G protein-coupled C3a receptors (C3aRs) in the immune system complement pathway. Activation of C3aR preve... | ||||
TP1304 | Compstatin | 206645-99-0 | 100% |
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Compstatin, a cyclic tridecapeptide, which was originally discovered from phage-display libraries, is a highly potent and selective C3 inhibitor. | ||||
T7497L | C3a 70-77 2TFA(63555-63-5(free base)) | T7497L | 98% |
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C3a 70-77 2TFA(63555-63-5(free base)) (Complement 3a (70-77)) is an octapeptide corresponding to the COOH terminus of C3a. | ||||
TP2180L | Compstatin control peptide acetate | 301544-78-5 | 98% |
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Compstatin control peptide acetate is an inhibitor of complement protein C3 by binding and inhibiting the cleavage of complement C3. | ||||
T24524 | NDT 9513727 | 439571-48-9 | 98% |
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NDT 9513727 is a potent, selective and competitive C5aR1 inverse agonist for the study of inflammatory and immune disorders. | ||||
T76702 | Sutimlimab | 2049079-64-1 | 98% |
Sutimlimab
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Sutimlimab is a novel monoclonal antibody targeting complement protein C1. Sutimlimab is commonly used as a C1 inhibitor to treat cold agglutina-associated hemol... | ||||
T76831 | Tesidolumab | 1531594-08-7 | 98% |
Tesidolumab
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Tesidolumab (LFG316) is a fully human IgG1/λ anti-C5 monoclonal antibody. Tesidolumab (LFG316) has an inhibitory effect on crovalimab and C5, blocking the cuttin... | ||||
T76867 | Ravulizumab | 1803171-55-2 | 98% |
Ravulizumab
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Ravulizumab (ALXN1210) is a humanized monoclonal antibody targeting complement factor 5 that specifically binds to human complement protein C5 with high affinity... | ||||
T38332 | Complement factor D-IN-2 | 1903742-34-6 | 98% |
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Complement factor D-IN-2 is an inhibitor of Complement factor D and reduces the excessive activation of complement factor D. | ||||
T40646 | Lipoteichoic acid | 56411-57-5 | 98% |
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Lipoteichoic acid, a polymer of Staphylococcus aureus cell wall, activates the complement system by inducing C3 and inhibiting CD55, and reduces fat deposition v... | ||||
T7776 | ADH-503 | 2055362-74-6 | 98% |
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ADH-503 (GB1275) is a potent agonist of the integrin CD11b to mitigate myeloid cell immunosuppression. | ||||
TP2296L | TLQP 21 acetate | 98% |
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TLQP 21 acetate is a potent agonist of G-protein-coupled receptor complement-3a receptor 1 (C3aR1). The EC50 values are 10.3 μM for mouse and 68.8 μM for human... | ||||
T17250 | W-54011 | 405098-33-1 | 98% |
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W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki: 2.2 nM). W-54011 inhibits C5a... |