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Calcium Channel

A calcium channel is an ion channel which shows selective permeability to calcium ions. It is sometimes synonymous with voltage-gated calcium channel, although there are also ligand-gated calcium channels.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T12205 Ned 19 874374-25-1 98.55%
Ned 19
Ned 19 is a selective membrane-permeant non competitive antagonist of NAADP and strongly inhibits tumor growth and vascularization as well as lung metastases in ...
TN2054 Periplocymarin 32476-67-8 98.54%
Periplocymarin
Periplocymarin is a cardiac glycoside with anticancer potential isolated from Periploca sepium and Periploca graeca.
T4054 Dantrolene sodium hemiheptahydrate 24868-20-0 98.52%
Dantrolene sodium hemiheptahydrate
Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium concentration...
T3524 Halofuginone hydrobromide 64924-67-0 98.5%
Halofuginone hydrobromide
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of...
T41233 Cis-22a 1819366-84-1 98.49%
Cis-22a
Cis-22a is a TRPV6 inhibitor (IC50 = 0.32 μM), which exhibits selectivity against related TRPV channels and calcium channels. cis-22a displays antiproliferative ...
T25701 Levosemotiadil 116476-16-5 98.47%
Levosemotiadil
Levosemotiadil(SA 3212) is a novel calcium antagonist and a very potent inhibitor of low-density lipoprotein oxidation.Levosemotiadil may be used to prevent leth...
T13154 Tiapamil hydrochloride 57010-32-9 98.47%
Tiapamil hydrochloride
Tiapamil hydrochloride is a blocker of calcium channel.
T3543 NS-638 150493-34-8 98.44%
NS-638
NS-638 is a Ca2+-channel blocker. It can block K+-stimulated intracellular Ca2+-elevation (IC50: 3.4 μM).
T4693 2-Aminoethyl diphenylborinate 524-95-8 98.43%
2-Aminoethyl diphenylborinate
2-Aminoethyl diphenylborinate (2-APB) is a chemical that acts to inhibit both IP3 receptors and TRP channels (although it activates TRPV1, TRPV2, & TRPV3 at high...
TN1757 Hypophyllanthin 33676-00-5 98.39%
Hypophyllanthin
Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
T11517 GV-58 1402821-41-3 98.34%
GV-58
GV-58 is a selective N- and P/Q-type Ca2+ channels agonist (EC50: 7.21/8.81 uM for N-type/P-Q-type Ca2+ channel). The inhibitory of GV-58 is 20-fold fewer for CD...
T15027 Cyclopiazonic acid 18172-33-3 98.3%
Cyclopiazonic acid
Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite (SM) made by A. flavus. Cyclopiazonic acid (CPA) is an endoplasmic reticulum calcium ATPase (Ca2+AT...
T29201 Z944 1199236-64-0 98.29%
Z944
Z944 is a T-type calcium channel blocker. Z944 delays the progression of seizures in the amygdala kindling model. Z944 disrupts prepulse inhibition in both epile...
T1221 Acetylcholine chloride 60-31-1 98.28%
Acetylcholine chloride
Acetylcholine Chloride is the chloride salt form of acetylcholine, a synthetic, quaternary amino alcohol with cholinergic properties. Acetylcholine chloride (Pil...
TQ0144 (S)-(-)-Bay-K-8644 98625-26-4 98.28%
(S)-(-)-Bay-K-8644
(S)-(-)-Bay-K-8644 ((S)-(-)-Bay K 8644) is an agonist of L-type Ca2+ channel and activates Ba2+ currents with an EC50 of 32 nM.
T2003 ISX-9 832115-62-5 98.26%
ISX-9
ISX-9 (Isoxazole 9) is necessary to activate neuron-specific genes as neurogenesis inducer.
T1730 NPS-2143 284035-33-2 98.24%
NPS-2143
NPS-2143 (SB 262470A) is a novel potent and selective antagonist of Ca(2+) receptor.
T10659 Ca2+ channel agonist 1 1402821-24-2 98.21%
Ca2+ channel agonist 1
Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2 (EC50s: 14.23 μM and 3.34 μM) and is used as a potential treatment for motor...
T6633 Ranolazine 95635-55-5 98.2%
Ranolazine
Ranolazine (RS 43285-003) is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina. It affects the sodium-dependent calcium cha...
TN1008 Psoralenoside 905954-17-8 98.17%
Psoralenoside
Psoralenoside is a natural product isolated from the fruits of Psoralea corylifolia, shows estrogen-like activity, osteoblastic proliferation accelerating activi...
Ned 19
T12205
Ned 19 is a selective membrane-permeant non competitive antagonist of NAADP and strongly inhibits tumor growth and vascularization as well as lung metastases in ...
Periplocymarin
TN2054
Periplocymarin is a cardiac glycoside with anticancer potential isolated from Periploca sepium and Periploca graeca.
Dantrolene sodium hemiheptahydrate
T4054
Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium concentration...
Halofuginone hydrobromide
T3524
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of...
Cis-22a
T41233
Cis-22a is a TRPV6 inhibitor (IC50 = 0.32 μM), which exhibits selectivity against related TRPV channels and calcium channels. cis-22a displays antiproliferative ...
Levosemotiadil
T25701
Levosemotiadil(SA 3212) is a novel calcium antagonist and a very potent inhibitor of low-density lipoprotein oxidation.Levosemotiadil may be used to prevent leth...
Tiapamil hydrochloride
T13154
Tiapamil hydrochloride is a blocker of calcium channel.
NS-638
T3543
NS-638 is a Ca2+-channel blocker. It can block K+-stimulated intracellular Ca2+-elevation (IC50: 3.4 μM).
2-Aminoethyl diphenylborinate
T4693
2-Aminoethyl diphenylborinate (2-APB) is a chemical that acts to inhibit both IP3 receptors and TRP channels (although it activates TRPV1, TRPV2, & TRPV3 at high...
Hypophyllanthin
TN1757
Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
GV-58
T11517
GV-58 is a selective N- and P/Q-type Ca2+ channels agonist (EC50: 7.21/8.81 uM for N-type/P-Q-type Ca2+ channel). The inhibitory of GV-58 is 20-fold fewer for CD...
Cyclopiazonic acid
T15027
Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite (SM) made by A. flavus. Cyclopiazonic acid (CPA) is an endoplasmic reticulum calcium ATPase (Ca2+AT...
Z944
T29201
Z944 is a T-type calcium channel blocker. Z944 delays the progression of seizures in the amygdala kindling model. Z944 disrupts prepulse inhibition in both epile...
Acetylcholine chloride
T1221
Acetylcholine Chloride is the chloride salt form of acetylcholine, a synthetic, quaternary amino alcohol with cholinergic properties. Acetylcholine chloride (Pil...
(S)-(-)-Bay-K-8644
TQ0144
(S)-(-)-Bay-K-8644 ((S)-(-)-Bay K 8644) is an agonist of L-type Ca2+ channel and activates Ba2+ currents with an EC50 of 32 nM.
ISX-9
T2003
ISX-9 (Isoxazole 9) is necessary to activate neuron-specific genes as neurogenesis inducer.
NPS-2143
T1730
NPS-2143 (SB 262470A) is a novel potent and selective antagonist of Ca(2+) receptor.
Ca2+ channel agonist 1
T10659
Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2 (EC50s: 14.23 μM and 3.34 μM) and is used as a potential treatment for motor...
Ranolazine
T6633
Ranolazine (RS 43285-003) is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina. It affects the sodium-dependent calcium cha...
Psoralenoside
TN1008
Psoralenoside is a natural product isolated from the fruits of Psoralea corylifolia, shows estrogen-like activity, osteoblastic proliferation accelerating activi...
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TargetMol