T12205 |
Ned 19
|
874374-25-1
|
98.55%
|
|
Ned 19 is a selective membrane-permeant non competitive antagonist of NAADP and strongly inhibits tumor growth and vascularization as well as lung metastases in ...
|
TN2054 |
Periplocymarin
|
32476-67-8
|
98.54%
|
|
Periplocymarin is a cardiac glycoside with anticancer potential isolated from Periploca sepium and Periploca graeca.
|
T4054 |
Dantrolene sodium hemiheptahydrate
|
24868-20-0
|
98.52%
|
|
Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium concentration...
|
T3524 |
Halofuginone hydrobromide
|
64924-67-0
|
98.5%
|
|
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of...
|
T41233 |
Cis-22a
|
1819366-84-1
|
98.49%
|
|
Cis-22a is a TRPV6 inhibitor (IC50 = 0.32 μM), which exhibits selectivity against related TRPV channels and calcium channels. cis-22a displays antiproliferative ...
|
T25701 |
Levosemotiadil
|
116476-16-5
|
98.47%
|
|
Levosemotiadil(SA 3212) is a novel calcium antagonist and a very potent inhibitor of low-density lipoprotein oxidation.Levosemotiadil may be used to prevent leth...
|
T13154 |
Tiapamil hydrochloride
|
57010-32-9
|
98.47%
|
|
Tiapamil hydrochloride is a blocker of calcium channel.
|
T3543 |
NS-638
|
150493-34-8
|
98.44%
|
|
NS-638 is a Ca2+-channel blocker. It can block K+-stimulated intracellular Ca2+-elevation (IC50: 3.4 μM).
|
T4693 |
2-Aminoethyl diphenylborinate
|
524-95-8
|
98.43%
|
|
2-Aminoethyl diphenylborinate (2-APB) is a chemical that acts to inhibit both IP3 receptors and TRP channels (although it activates TRPV1, TRPV2, & TRPV3 at high...
|
TN1757 |
Hypophyllanthin
|
33676-00-5
|
98.39%
|
|
Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
|
T11517 |
GV-58
|
1402821-41-3
|
98.34%
|
|
GV-58 is a selective N- and P/Q-type Ca2+ channels agonist (EC50: 7.21/8.81 uM for N-type/P-Q-type Ca2+ channel). The inhibitory of GV-58 is 20-fold fewer for CD...
|
T15027 |
Cyclopiazonic acid
|
18172-33-3
|
98.3%
|
|
Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite (SM) made by A. flavus. Cyclopiazonic acid (CPA) is an endoplasmic reticulum calcium ATPase (Ca2+AT...
|
T29201 |
Z944
|
1199236-64-0
|
98.29%
|
|
Z944 is a T-type calcium channel blocker. Z944 delays the progression of seizures in the amygdala kindling model. Z944 disrupts prepulse inhibition in both epile...
|
T1221 |
Acetylcholine chloride
|
60-31-1
|
98.28%
|
|
Acetylcholine Chloride is the chloride salt form of acetylcholine, a synthetic, quaternary amino alcohol with cholinergic properties. Acetylcholine chloride (Pil...
|
TQ0144 |
(S)-(-)-Bay-K-8644
|
98625-26-4
|
98.28%
|
|
(S)-(-)-Bay-K-8644 ((S)-(-)-Bay K 8644) is an agonist of L-type Ca2+ channel and activates Ba2+ currents with an EC50 of 32 nM.
|
T2003 |
ISX-9
|
832115-62-5
|
98.26%
|
|
ISX-9 (Isoxazole 9) is necessary to activate neuron-specific genes as neurogenesis inducer.
|
T1730 |
NPS-2143
|
284035-33-2
|
98.24%
|
|
NPS-2143 (SB 262470A) is a novel potent and selective antagonist of Ca(2+) receptor.
|
T10659 |
Ca2+ channel agonist 1
|
1402821-24-2
|
98.21%
|
|
Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2 (EC50s: 14.23 μM and 3.34 μM) and is used as a potential treatment for motor...
|
T6633 |
Ranolazine
|
95635-55-5
|
98.2%
|
|
Ranolazine (RS 43285-003) is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina. It affects the sodium-dependent calcium cha...
|
TN1008 |
Psoralenoside
|
905954-17-8
|
98.17%
|
|
Psoralenoside is a natural product isolated from the fruits of Psoralea corylifolia, shows estrogen-like activity, osteoblastic proliferation accelerating activi...
|