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Calcium Channel

A calcium channel is an ion channel which shows selective permeability to calcium ions. It is sometimes synonymous with voltage-gated calcium channel, although there are also ligand-gated calcium channels.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T21263 Amlodipine maleate 88150-47-4 99.4%
Amlodipine maleate
Amlodipine maleate (Amvaz) is an orally active dihydropyridine calcium channel blocker that inhibits calcium inward flow by blocking voltage-dependent L-type cal...
T23097 O-1602 317321-41-8 99.4%
O-1602
O-1602 is a novel GPR55 agonist, an atypical cannabinoid associated with the central nervous system and obesity, and is a candidate compound for the treatment of...
TN3466 Atherosperminine 5531-98-6 99.4%
Atherosperminine
Atherosperminine shows cholinesterase inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Atherosperminine shows strong ant...
T0702 Gabapentin 60142-96-3 99.39%
Gabapentin
Gabapentin (Neurontin) is an Anti-epileptic Agent. The physiologic effect of gabapentin is by means of Decreased Central Nervous System Disorganized Electrical A...
T28164 Nexopamil 136033-49-3 99.39%
Nexopamil
Nexopamil (LU-49938) is a calcium channel antagonist and a 5-hydroxytryptamine 2A receptor antagonist. Nexopamil inhibits 5-HT-induced contraction and proliferat...
T0825 Ebselen 60940-34-3 99.38%
Ebselen
Ebselen (CCG-39161) is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimet...
T10690 Cav 2.2 blocker 1 1567335-29-8 99.38%
Cav 2.2 blocker 1
Cav 2.2 blocker 1 is an N-type calcium channel (Cav 2.2; IC50: 1 nM) blocker for the treatment of pain.
T28974 Ticolubant 154413-61-3 99.33%
Ticolubant
Ticolubant is orally active leukotriene B4 antagonist with high affinity for the human neutrophil LTB4 receptor (Ki = 0.78 nM), blocks LTB4-induced Ca2+ migrati...
T8448 ZSET1446 887603-94-3 99.32%
ZSET1446
ZSET1446 (ST-101) is a T-type calcium channel activator potentially for the treatment of learning deficits in various types of Alzheimer disease (AD) models.
T1146 Nifedipine 21829-25-4 99.30%
Nifedipine
Nifedipine (Procardia) is a dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myoca...
TQ0302 Thapsigargin 67526-95-8 99.3%
Thapsigargin
Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer. Thapsigarg...
T5632 Suvecaltamide 953778-58-0 99.29%
Suvecaltamide
Suvecaltamide (MK-8998) as potent inhibitors of T-type calcium channels.
T27087 Cronidipine 113759-50-5 99.25%
Cronidipine
Cronidipine (LF 20254), a calcium channel antagonist, is used potentially for the treatment of hypertension and myocardia ischemia.
TP1852L Myomodulin acetate(110570-93-9 free base) TP1852L 99.24%
Myomodulin acetate(110570-93-9 free base)
Myomodulin acetate is present in two identified aplysia neurons that contain myomodulin A the ARC motor neuron B16 and the abdominal neuron L10.
TN1136 Procyanidin A1 103883-03-0 99.23%
Procyanidin A1
Procyanidin A1 (Proanthocyanidin A1) has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2+; influx from an intern...
T68123 Oxodipine 90729-41-2 99.22%
Oxodipine
Oxodipine, a dihydropyridine-type calcium antagonist , inhibited KCl-induced aortic contraction in rabbits and reduced cardiac force in less potent rat ventricul...
T77640 Ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate 99429-64-8 99.19%
Ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate
ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate inhibits NAD(P)H: quinone oxidoreductase 1.
T3465L Vesnarinone HCl T3465L 99.17%
Vesnarinone HCl
Vesnarinone HCl (OPC-8212 HCl) is an orally active phosphodiesterase 3 (PDE3) inhibitor.Vesnarinone HCl modulates calcium and potassium ions, increasing calcium ...
T12321 ORM-10103 488847-28-5 99.15%
ORM-10103
ORM-10103 is a novel potent and selective inhibitor of the Na+/Ca2+ exchanger (NCX).ORM-10103 inhibited NCX currents with estimated IC50 values of 55 and 67 nM a...
T4564 Ethacrynic acid 58-54-8 99.15%
Ethacrynic acid
Ethacrynic acid (Edecrin) is a nonsulfonamide loop diuretic that inhibits the activity of the Na+/K+/2Cl- cotransporter NKCC2 in the thick ascending limb of the ...
Amlodipine maleate
T21263
Amlodipine maleate (Amvaz) is an orally active dihydropyridine calcium channel blocker that inhibits calcium inward flow by blocking voltage-dependent L-type cal...
O-1602
T23097
O-1602 is a novel GPR55 agonist, an atypical cannabinoid associated with the central nervous system and obesity, and is a candidate compound for the treatment of...
Atherosperminine
TN3466
Atherosperminine shows cholinesterase inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Atherosperminine shows strong ant...
Gabapentin
T0702
Gabapentin (Neurontin) is an Anti-epileptic Agent. The physiologic effect of gabapentin is by means of Decreased Central Nervous System Disorganized Electrical A...
Nexopamil
T28164
Nexopamil (LU-49938) is a calcium channel antagonist and a 5-hydroxytryptamine 2A receptor antagonist. Nexopamil inhibits 5-HT-induced contraction and proliferat...
Ebselen
T0825
Ebselen (CCG-39161) is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimet...
Cav 2.2 blocker 1
T10690
Cav 2.2 blocker 1 is an N-type calcium channel (Cav 2.2; IC50: 1 nM) blocker for the treatment of pain.
Ticolubant
T28974
Ticolubant is orally active leukotriene B4 antagonist with high affinity for the human neutrophil LTB4 receptor (Ki = 0.78 nM), blocks LTB4-induced Ca2+ migrati...
ZSET1446
T8448
ZSET1446 (ST-101) is a T-type calcium channel activator potentially for the treatment of learning deficits in various types of Alzheimer disease (AD) models.
Nifedipine
T1146
Nifedipine (Procardia) is a dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myoca...
Thapsigargin
TQ0302
Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer. Thapsigarg...
Suvecaltamide
T5632
Suvecaltamide (MK-8998) as potent inhibitors of T-type calcium channels.
Cronidipine
T27087
Cronidipine (LF 20254), a calcium channel antagonist, is used potentially for the treatment of hypertension and myocardia ischemia.
Myomodulin acetate(110570-93-9 free base)
TP1852L
Myomodulin acetate is present in two identified aplysia neurons that contain myomodulin A the ARC motor neuron B16 and the abdominal neuron L10.
Procyanidin A1
TN1136
Procyanidin A1 (Proanthocyanidin A1) has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2+; influx from an intern...
Oxodipine
T68123
Oxodipine, a dihydropyridine-type calcium antagonist , inhibited KCl-induced aortic contraction in rabbits and reduced cardiac force in less potent rat ventricul...
Ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate
T77640
ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate inhibits NAD(P)H: quinone oxidoreductase 1.
Vesnarinone HCl
T3465L
Vesnarinone HCl (OPC-8212 HCl) is an orally active phosphodiesterase 3 (PDE3) inhibitor.Vesnarinone HCl modulates calcium and potassium ions, increasing calcium ...
ORM-10103
T12321
ORM-10103 is a novel potent and selective inhibitor of the Na+/Ca2+ exchanger (NCX).ORM-10103 inhibited NCX currents with estimated IC50 values of 55 and 67 nM a...
Ethacrynic acid
T4564
Ethacrynic acid (Edecrin) is a nonsulfonamide loop diuretic that inhibits the activity of the Na+/K+/2Cl- cotransporter NKCC2 in the thick ascending limb of the ...
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TargetMol