T3047 |
SRT3109
|
1204707-71-0
|
99.92%
|
|
SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.
|
T0617 |
Nicotinamide N-oxide
|
1986-81-8
|
99.9%
|
|
Nicotinamide N-oxide (Nicotinamide 1-oxide) is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD...
|
T3327 |
Artemotil
|
75887-54-6
|
99.76%
|
|
Artemotil (SM-227) is a new, fast-acting antimalarial drug.
|
T17208 |
USL311
|
1373268-67-7
|
99.73%
|
|
USL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4. USL311 inhibits CXCR4 activation an...
|
T5207 |
LIT927
|
2172879-52-4
|
99.73%
|
|
LIT927 (LIT-927) is an orally active CXCL12 neutraligand (Ki: 267 nM for CXCL12 binding to CXCR4).
|
TP2112L |
TC14012 acetate
|
TP2112L
|
99.71%
|
|
TC14012 acetate is a serum-stable derivative of T140 which is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM. TC14012 is also a potent C...
|
TP1348 |
FC131 TFA (606968-52-9 free base)
|
842166-42-1
|
99.67%
|
|
FC131 TFA (606968-52-9 free base) (FC131 TFA) is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hiv act...
|
T4032 |
MSX-127
|
6616-56-4
|
99.61%
|
|
MSX-127 elicites positive response in peptide CXCR4.
|
T7499 |
TAK-779
|
229005-80-5
|
99.58%
|
|
TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).
|
T8497 |
SX-682
|
1648843-04-2
|
99.57%
|
|
SX-682 is a potent, selective and orally bioavailable inhibitor of CXCR1/2 ,has the potential to treat castration-resistant prostate cancer.
|
T10905 |
CXCR2-IN-1
|
1873376-49-8
|
99.53%
|
|
CXCR2-IN-1 has a pIC50 of 9.3 and is a CXCR2 antagonist of the central nervous system penetration agent.
|
T39078 |
CXCR7 antagonist-1
|
1613021-99-0
|
99.51%
|
|
CXCR7 antagonist-1 is a specific antagonist of the binding of the SDF-1 chemokine or I-TAC to the chemokine receptor CXCR7. CXCR7 antagonist-1 prevents tumor cel...
|
T13324 |
VUF11207 fumarate
|
1785665-61-3
|
99.5%
|
|
VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).
|
T4033 |
MSX-130
|
4051-59-6
|
99.44%
|
|
MSX-130 is CXCR4 Antagonist.
|
T68052 |
Delmetacin
|
16401-80-2
|
99.42%
|
|
Delmetacin (Demethacin) is a non-steroidal anti-inflammatory compound with anti-inflammatory and analgesic activity and inhibitory effects on the CXC chemokine r...
|
T25131 |
AZD8309
|
333742-48-6
|
99.17%
|
|
AZD8309 is a potent, orally available antagonist of the chemokine receptor CXCR2 that regulates neutrophil transport, significantly reduces MPO in the pancreas a...
|
T7208 |
AMD 3465 hexahydrobromide
|
185991-07-5
|
99.03%
|
|
AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.
|
T7681 |
AZD-5069
|
878385-84-3
|
98.85%
|
|
AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).
|
T3396 |
Baohuoside I
|
113558-15-9
|
98.85%
|
|
Baohuoside I (Icariside-II) is a component of Epimedium koreanum, exhibits anti-inflammatory activity and anti-osteoporosis activities.
|
T2477 |
UNBS5162
|
956590-23-1
|
98.38%
|
|
UNBS5162 (UNBS-5162) is a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers.
|