T7698 |
BS194
|
1092443-55-4
|
99.64%
|
|
BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.
|
T12642 |
(R)-Simurosertib
|
1330782-69-8
|
99.64%
|
|
(R)-Simurosertib ((R)-TAK-931) is an inhibitor of the ATP-competitive cell division cycle 7 (CDC7) kinase.
|
T22106 |
MLS-573151
|
10179-57-4
|
99.64%
|
|
MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM). It is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 ...
|
T8430 |
Senexin B
|
1449228-40-3
|
99.63%
|
|
Senexin B is a potent and selective inhibitor of CDK8/19(CDK8 and CDK19 with Kds of 140 nM and 80 nM).
|
T8930 |
CID44216842
|
1222513-26-9
|
99.63%
|
|
CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM...
|
T61439 |
DSS30
|
883027-32-5
|
99.61%
|
|
DSS30 is a P25/CDK5 inhibitor.DSS30 acts by inhibiting the phosphorylation of amyloid precursor protein cleaving enzyme 1 (BACEl), which reduces the secretion of...
|
T3166 |
VX-11e
|
896720-20-0
|
99.6%
|
|
VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; antitumor agent.
|
T21720 |
GP-82996
|
359886-84-3
|
99.57%
|
|
GP-82996 (CINK4) (CINK4) is a pharmacological inhibitor of CDK4/6. GP-82996 has IC 50 s of 1.5, 5.6 and 25 μM for CDK4/cyclin D1, CDK6/cyclin D1 and Cdk5/p35, re...
|
T15732 |
Ribociclib succinate
|
1374639-75-4
|
99.57%
|
|
Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively). It also is over 1,000-fold less potent again...
|
T6139L |
A-674563 2HCl(552325-73-2(fb-2hcl))
|
T6139L
|
99.57%
|
|
A-674563 2HCl is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
|
T23589 |
9-Isopropylolomoucine
|
158982-15-1
|
99.56%
|
|
9-Isopropylolomoucine (N9-Isopropylolomoucine), a cell cycle protein-dependent kinase inhibitor, is a thiopurine.
|
T15454 |
GW843682X
|
660868-91-7
|
99.56%
|
|
GW843682X (GW843682) is a selective and ATP-competitive inhibitor of PLK1 and PLK3 (IC50s = 2.2 nM and 9.1 nM).
|
T39752 |
CDK12-IN-2
|
2244987-03-7
|
99.54%
|
|
CDK12-IN-2 (CDK12 inhibitor 2) is an effective and selective inhibitor of CDK12 with an IC50 of 52 nM, >100 μM, >10 μM and 16 μM for CDK12, CDK2, CDK7, and CDK9....
|
T2029 |
Bohemine
|
189232-42-6
|
99.53%
|
|
Bohemine is a cyclin-dependent kinase inhibitor.
|
TQ0078 |
CDK-IN-2
|
1269815-17-9
|
99.52%
|
|
CDK-IN-2 (CDK inhibitor II) is a potent and specific CDK9 inhibitor (IC50: <8 nM).
|
T22461 |
YKL-5-124
|
1957203-01-8
|
99.5%
|
|
YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displays ...
|
T6177 |
PF-562271 besylate
|
939791-38-5
|
99.5%
|
|
PF-562271 besylate (PF-00562271 Besylate) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK a...
|
T8801 |
SRI-29329
|
2086809-58-5
|
99.49%
|
|
SRI-29329 is a potent, specific inhibitor of CDC-like kinase (with IC50 of 78 nM, 16 nM and 86 nM for CLK1, CLK2 and CLK4, respectively).
|
T7444 |
6-(Dimethylamino)purine
|
938-55-6
|
99.49%
|
|
6-(Dimethylamino)purine (N,N-Dimethyladenine) is a serine threonine protein kinase and CDK inhibitor
|
T77619 |
WAY-322243
|
332939-32-9
|
99.47%
|
|
WAY-322243 has antibacterial and anti-inflammatory activity and has an inhibitory effect on CLK-1, which can be used to study Alzheimer's disease.
|