Home Tools
Log in
Cart

CDK

Cyclin-dependent kinases (CDKs) are the families of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells.They are present in all known eukaryotes, and their regulatory function in the cell cycle has been evolutionarily conserved.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T9117 BSJ-4-116 2519823-34-6 99.09%
BSJ-4-116
BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. It downregulates DDR genes through a premature termination of transcript...
T4321 Indisulam 165668-41-7 99.07%
Indisulam
Indisulam (E 7070) is a carbonic anhydrase inibitor and Antitumor CDK inhibitor. Indisulam targets the G1 phase of the cell cycle by depleting cyclin E. inducing...
T6563 LDC000067 1073485-20-7 99.07%
LDC000067
LDC000067 (LDC067) is a highly specific and selective CDK9 inhibitor with an IC50 value of 44±10 nM.
T77613 SNX7 685097-43-2 99.05%
SNX7
SNX7 (WAY-323879) is an inhibitor of the cell cycle protein-dependent kinase inhibitor (CDKI) pathway. SNX7 can be utilized as a tool for investigating the aging...
T14918 CDK9-IN-2 1263369-28-3 99%
CDK9-IN-2
CDK9-IN-2 is a special CDK9 inhibitor extracted from patent WO/2012131594A1 (compound CDKI(8)) and has an IC50 of 5 nM and 7 nM in A2058 skin cell line (72 hours...
T72048 CDK8-IN-12 2613307-67-6 98.97%
CDK8-IN-12
CDK8-IN-12 is a selective, potent and orally active inhibitor of CDK8 (Ki: 14 nM) and is an anti-cancer agent. CDK8-IN-12 inhibits GSK-3α, GSK-3β and PCK-θ with ...
T8576 P18IN011 77408-67-4 98.94%
P18IN011
P18IN011 (P18IN011 - CAS 77408-67-4 - Calbiochem) is a novel inhibitor of p18(INK4C).
TN1299 Desmethylglycitein 17817-31-1 98.93%
Desmethylglycitein
Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which has antioxidant...
T4205 AG-494 133550-35-3 98.9%
AG-494
AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.
T2670 ML167 1285702-20-6 98.85%
ML167
ML167 (CID44968231) is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor.
T21966 MeBIO 667463-95-8 98.84%
MeBIO
MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.
T36933 Cdk2 Inhibitor II 222035-13-4 98.84%
Cdk2 Inhibitor II
Cdk2 Inhibitor II is a selective and potent CDK2 inhibitor50 at 60 nM.
T70388L (R)-Enitociclib 1610408-96-2 98.82%
(R)-Enitociclib
(R)-Enitociclib, an enantiomer of BAY-1251152, is a CDK9 inhibitor with anticancer activity.
T14778 BRD6989 642008-81-9 98.82%
BRD6989
BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant C...
T10746 CDK9-IN-8 2105956-51-0 98.77%
CDK9-IN-8
CDK9-IN-8 is a highly potent and selective CDK9 inhibitor (IC50: 12 nM).
T77341 GSK-3 inhibitor 4 2227279-83-4 98.77%
GSK-3 inhibitor 4
GSK-3 inhibitor 4 is an orally active and brain-permeable triple inhibitor of GSK-3, CDK2 and CDK5 with inhibitory effects on GSK-3β, GSK-3α, CDK2 and CDK5, with...
T1901 (E/Z)-TG003 300801-52-9 98.73%
(E/Z)-TG003
(E/Z)-TG003 is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor.
T23897 CLK1/2-IN-3 1005784-60-0 98.71%
CLK1/2-IN-3
CLK1/2-IN-3 (Cpd-3) is a potent and selective CLK1 and CLK2 inhibitor with antiproliferative activity and inhibits the activities of CLK1, CLK2, SRPK1, SRPK2, an...
TQ0053 Fadraciclib 1070790-89-4 98.71%
Fadraciclib
Fadraciclib (CYC065) is an orally available, second-generation ATP-competitive inhibitor of CDK2/CDK9 kinases (IC50s: 5/26 nM).
T6940 PHA-767491 hydrochloride 942425-68-5 98.69%
PHA-767491 hydrochloride
PHA-767491 hydrochloride (CAY-10572 hydrochloride) is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM). It has ~20-fold selectivity against...
BSJ-4-116
T9117
BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. It downregulates DDR genes through a premature termination of transcript...
Indisulam
T4321
Indisulam (E 7070) is a carbonic anhydrase inibitor and Antitumor CDK inhibitor. Indisulam targets the G1 phase of the cell cycle by depleting cyclin E. inducing...
LDC000067
T6563
LDC000067 (LDC067) is a highly specific and selective CDK9 inhibitor with an IC50 value of 44±10 nM.
SNX7
T77613
SNX7 (WAY-323879) is an inhibitor of the cell cycle protein-dependent kinase inhibitor (CDKI) pathway. SNX7 can be utilized as a tool for investigating the aging...
CDK9-IN-2
T14918
CDK9-IN-2 is a special CDK9 inhibitor extracted from patent WO/2012131594A1 (compound CDKI(8)) and has an IC50 of 5 nM and 7 nM in A2058 skin cell line (72 hours...
CDK8-IN-12
T72048
CDK8-IN-12 is a selective, potent and orally active inhibitor of CDK8 (Ki: 14 nM) and is an anti-cancer agent. CDK8-IN-12 inhibits GSK-3α, GSK-3β and PCK-θ with ...
P18IN011
T8576
P18IN011 (P18IN011 - CAS 77408-67-4 - Calbiochem) is a novel inhibitor of p18(INK4C).
Desmethylglycitein
TN1299
Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which has antioxidant...
AG-494
T4205
AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.
ML167
T2670
ML167 (CID44968231) is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor.
MeBIO
T21966
MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.
Cdk2 Inhibitor II
T36933
Cdk2 Inhibitor II is a selective and potent CDK2 inhibitor50 at 60 nM.
(R)-Enitociclib
T70388L
(R)-Enitociclib, an enantiomer of BAY-1251152, is a CDK9 inhibitor with anticancer activity.
BRD6989
T14778
BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant C...
CDK9-IN-8
T10746
CDK9-IN-8 is a highly potent and selective CDK9 inhibitor (IC50: 12 nM).
GSK-3 inhibitor 4
T77341
GSK-3 inhibitor 4 is an orally active and brain-permeable triple inhibitor of GSK-3, CDK2 and CDK5 with inhibitory effects on GSK-3β, GSK-3α, CDK2 and CDK5, with...
(E/Z)-TG003
T1901
(E/Z)-TG003 is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor.
CLK1/2-IN-3
T23897
CLK1/2-IN-3 (Cpd-3) is a potent and selective CLK1 and CLK2 inhibitor with antiproliferative activity and inhibits the activities of CLK1, CLK2, SRPK1, SRPK2, an...
Fadraciclib
TQ0053
Fadraciclib (CYC065) is an orally available, second-generation ATP-competitive inhibitor of CDK2/CDK9 kinases (IC50s: 5/26 nM).
PHA-767491 hydrochloride
T6940
PHA-767491 hydrochloride (CAY-10572 hydrochloride) is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM). It has ~20-fold selectivity against...
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
TargetMol