Cat. No. | Product name | CAS No. | Purity | Chemical Structure |
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T7624 | DAPTA | 106362-34-9 | 100% |
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DAPTA (Adaptavir) is an inhibitor of CCR5, shows potent anti-HIV activities. | ||||
T6016 | Maraviroc | 376348-65-1 | 100% |
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Maraviroc (Selzentry) is a C-C Chemokine Receptor Type 5 (CCR5) antagonist, and for MIP-1α(IC50=3.3 nM), MIP-1β (IC50=7.2 nM) and RANTES(IC50=5.2 nM).Maraviroc i... | ||||
T15253 | CCX354 | 1010073-75-2 |
|
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CCX354 (CCR1 antagonist 1) is a potent small molecule CCR1 antagonist with anti-inflammatory activity for the treatment of rheumatoid arthritis. | ||||
T11699 | J-113863 | 353791-85-2 |
|
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J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against... | ||||
T4674 | SB297006 | 58816-69-6 | 98% |
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SB297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. ... | ||||
T9942 | WAY-639418 | 643042-43-7 | 98% |
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WAY-639418 has potential anti-inflammatory and anti-HIV activity and can be used to study CCR5-mediated inflammatory and immunomodulatory diseases. | ||||
TN1599 | Eburicoic acid | 560-66-7 | 98% |
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Eburicoic acid (ZINC4655149) exhibits anti-inflammatory and antioxidant activity thereby protecting the liver from CCl4-induced hepatic damage and can be used in... | ||||
T36478 | BI-6901 | 2040401-92-9 | 98% |
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BI-6901 is a CCR10 antagonist. In a mouse model of DNFB exposure hypersensitivity, BI 6901 displays its anti-inflammatory response in a dose-dependent manner. | ||||
T14688 | BMS CCR2 22 | 445479-97-0 | 98% |
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BMS CCR2 22 is a potent and selective antagonist of CCR2 with calcium flux IC50 of 18 nM, chemotaxis IC50 of 1 nM, and binding IC50 of 5.1 nM. | ||||
T77059 | Leronlimab | 674782-26-4 | 98% |
Leronlimab
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Leronlimab (PRO 140) is a humanized IgG4 anti-CCR5 monoclonal antibody. leronlimumab has both anti-HIV and anti-tumor activity, inhibiting CCR-mediated HIV-1 vir... | ||||
T77118 | Plozalizumab | 1610761-46-0 | 98% |
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Plozalizumab (MLN-1202) is a humanized selective and potent anti-CCR2 antibody.Plozalizumab has antitumor activity.Plozalizumab is used in the study of malignant... | ||||
T13114 | CCR2 antagonist 4 | 226226-39-7 | 98% |
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CCR2 antagonist 4 (Teijin compound 1) is a potent and specific antagonist of CCR2(IC50s of 180 nM), and potently inhibits MCP-1-induced chemotaxis(IC50 of 24 nM)... | ||||
T5384 | RS 504393 | 300816-15-3 | 98% |
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RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1). | ||||
T60336 | CCR4 antagonist 3-1 | 1957-01-3 | 98% |
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CCR4 antagonist 3-1 is a less active chemokine receptor 4 (CCR4) antagonist that inhibits [125I]TARC (thymus and activation-regulated chemokine) with an IC50 val... |