Home Tools
Log in
Cart

Autophagy

Autophagy is the natural, regulated mechanism of the cell that removes unnecessary or disfunctional components. It allows the orderly degradation and recycling of cellular components. Three forms of autophagy are commonly described: macroautophagy, microautophagy, and chaperone-mediated autophagy (CMA). In macroautophagy, expendable cytoplasmic constituents are targeted and isolated from the rest of the cell within a double-membraned vesicle known as an autophagosome, which, in time, fuses with an available lysosome, bringing its specialty process of waste management and disposal; and eventually the contents of the vesicle (now called an autolysosome) are degraded and recycled.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T0213 Thalidomide 50-35-1
Thalidomide
Thalidomide (Thalomid) is a synthetic derivative of glutamic acid (alpha-phthalimido-glutarimide) with teratogenic, immunomodulatory, anti-inflammatory and anti-...
T1939 DMOG 89464-63-1
DMOG
DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.
T2998 Dihydromyricetin 27200-12-0
Dihydromyricetin
Dihydromyricetin (Ampelopsin) is a natural antioxidant flavonoid from Ampelopsis grossedentata. Dihydromyricetin is a potent inhibitor of dihydropyrimidinase wit...
T5070 LC3-mHTT-IN-AN2 7758-73-8
LC3-mHTT-IN-AN2
LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) is found in the plant Passiflora serratodigitata with the antibacterial activity.
T2166 TWS119 601514-19-6
TWS119
TWS119 is a GSK-3β inhibitor; capable of inducing neuronal differentiation
T0078L Lapatinib ditosylate monohydrate 388082-78-8
Lapatinib ditosylate monohydrate
Lapatinib ditosylate (Lapatinib tosilate) monohydrate is a tyrosine kinase receptor inhibitor used in the therapy of advanced breast cancer and other solid tumor...
T0070 Pentoxifylline 6493-05-6
Pentoxifylline
Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodieste...
T6991 Nitroprusside disodium dihydrate 13755-38-9
Nitroprusside disodium dihydrate
Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) is a potent vasodilator working through releasing NO spontaneously in blood.
T2830 Betulinic acid 472-15-1
Betulinic acid
Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has ...
TN1141 Isodeoxyelephantopin 38927-54-7
Isodeoxyelephantopin
Isodeoxyelephantopin exerts antitumor effects on several cancer cells by inducing apoptosis , cell cycle arrest , and inhibiting proliferation. It enhances apopt...
T6053 Turofexorate Isopropyl 629664-81-9
Turofexorate Isopropyl
Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM
T7697 BIX-01294 935693-62-2
BIX-01294
BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).
T3105 PFK-158 1462249-75-7
PFK-158
PFK-158 is an effective and specific inhibitor PFKFB3.
T6036 Brivanib 649735-46-6 98%
Brivanib
Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR...
T20597 Alginic acid 9005-32-7 98%
Alginic acid
Alginic acid (Snow acid algin G) is a natural polysaccharide extracted from brown seaweeds with anti-anaphylactic and anti-inflammatory activities. Alginic acid ...
TN7224 2,2'-Dihydroxy chalcone 15131-80-3 98%
2,2'-Dihydroxy chalcone
2,2'-Dihydroxy chalcone is a potent inhibitor of β-glucuronidase (IC50=1.6±0.2 μM) and lysozyme (IC50=1.4±0.2 μM) release from rat neutrophils stimulated with fM...
T18992 Fluorescein Biotin 134759-22-1 98%
Fluorescein Biotin
Fluorescein Biotin is a biotin-substituting fluorescent dye that detects and quantifies biotin binding sites by fluorescence or absorbance.Fluorescein Biotin und...
T5172 AZ304 942507-42-8 98%
AZ304
AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).
T4001 Euxanthone 529-61-3 98%
Euxanthone
Euxanthone (1,7-Dihydroxyxanthone), an xanthone derivative extracted from the roots of Polygala tenuifolia Willd, has antitumour, neuroprotective and vasorelaxan...
T4252 ML327 1883510-31-3 98%
ML327
ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).
Thalidomide
T0213
Thalidomide (Thalomid) is a synthetic derivative of glutamic acid (alpha-phthalimido-glutarimide) with teratogenic, immunomodulatory, anti-inflammatory and anti-...
DMOG
T1939
DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.
Dihydromyricetin
T2998
Dihydromyricetin (Ampelopsin) is a natural antioxidant flavonoid from Ampelopsis grossedentata. Dihydromyricetin is a potent inhibitor of dihydropyrimidinase wit...
LC3-mHTT-IN-AN2
T5070
LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) is found in the plant Passiflora serratodigitata with the antibacterial activity.
TWS119
T2166
TWS119 is a GSK-3β inhibitor; capable of inducing neuronal differentiation
Lapatinib ditosylate monohydrate
T0078L
Lapatinib ditosylate (Lapatinib tosilate) monohydrate is a tyrosine kinase receptor inhibitor used in the therapy of advanced breast cancer and other solid tumor...
Pentoxifylline
T0070
Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodieste...
Nitroprusside disodium dihydrate
T6991
Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) is a potent vasodilator working through releasing NO spontaneously in blood.
Betulinic acid
T2830
Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has ...
Isodeoxyelephantopin
TN1141
Isodeoxyelephantopin exerts antitumor effects on several cancer cells by inducing apoptosis , cell cycle arrest , and inhibiting proliferation. It enhances apopt...
Turofexorate Isopropyl
T6053
Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM
BIX-01294
T7697
BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).
PFK-158
T3105
PFK-158 is an effective and specific inhibitor PFKFB3.
Brivanib
T6036
Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR...
Alginic acid
T20597
Alginic acid (Snow acid algin G) is a natural polysaccharide extracted from brown seaweeds with anti-anaphylactic and anti-inflammatory activities. Alginic acid ...
2,2'-Dihydroxy chalcone
TN7224
2,2'-Dihydroxy chalcone is a potent inhibitor of β-glucuronidase (IC50=1.6±0.2 μM) and lysozyme (IC50=1.4±0.2 μM) release from rat neutrophils stimulated with fM...
Fluorescein Biotin
T18992
Fluorescein Biotin is a biotin-substituting fluorescent dye that detects and quantifies biotin binding sites by fluorescence or absorbance.Fluorescein Biotin und...
AZ304
T5172
AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).
Euxanthone
T4001
Euxanthone (1,7-Dihydroxyxanthone), an xanthone derivative extracted from the roots of Polygala tenuifolia Willd, has antitumour, neuroprotective and vasorelaxan...
ML327
T4252
ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).
1 ... 44 45 46 47 48
TargetMol