Akt

Protein kinase B (PKB), also known as Akt, is a serine/threonine-specific protein kinase that plays a key role in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration.

Cat. No.	Product name	CAS No.	Purity
T2895	Lupeol	545-47-1	99.31%
T2895	Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity.
T1920	Capivasertib	1143532-39-1	99.29%
T1920	Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity. Capivasertib h...
T72968	ZINC00640089	667880-11-7	99.27%
T72968	ZINC00640089 is a selective lipid carrier protein-2 (LCN2) inhibitor. ZINC00640089 inhibited cell proliferation and cell viability, and reduced AKT phosphorylati...
T24398	Lenaldekar	418800-15-4	99.25%
T24398	Lenaldekar (LDK) inhibits T-cell expansion and autoimmune encephalomyelitis. Lenaldekar causes dephosphorylation of members of the PI3 kinase/AKT/mTOR pathway an...
T6139	A-674563	552325-73-2	99.21%
T6139	A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
T6303	CCT128930	885499-61-6	99.18%
T6303	CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, 28-fold greater selectivity for Akt2 than the closely related PKA kinas...
T2S2215	Crebanine	25127-29-1	99.17%
T2S2215	1. Crebanine iv 5mg/kg can eonvert BaCl_2-induced arrhythmia into sinus rhythm in rats, and can significantly increase the tolerant dose of aconitine to produce ...
TN1433	Batatasin III	56684-87-8	99.16%
TN1433	Batatasin III inhibits cancer migration and invasion by suppressing epithelial to mesenchymal transition and FAK-AKT signals and possesses anti-cancer activities...
T3826	Polygalasaponin F	882664-74-6	99.15%
T3826	Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and re...
T8969	API-1	36707-00-3	99.07%
T8969	API-1 (NSC-177223) is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .
T2790	Oridonin	28957-04-2	99.04%
T2790	Oridonin (NSC-250682) is a diterpenoid isolated from Rabdosia rubescens with anti-tumor, anti-bacterial and anti-inflammatory effects. It acts as an inhibitor of...
T6252	Ipatasertib	1001264-89-6	99.03%
T6252	Ipatasertib (GDC-0068) (GDC-0068), a highly specific pan-Akt inhibitor, targets Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM, respectively.
T2482	AT13148	1056901-62-2	99%
T2482	AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.
TN1990	Norathyriol	3542-72-1	98.93%
TN1990	Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.
T39988	6'-GNTI dihydrochloride	2410327-94-3	98.91%
T39988	6'-GNTI dihydrochloride is a κ-opioid receptor (KOR) agonist that favors activation of G-protein-mediated signaling over recruitment of β-aspirin 2. 6'-GNTI dihy...
T10276L	AKT Kinase Inhibitor HCl		98.87%
T10276L	AKT Kinase Inhibitor HCl is an Akt inhibitor with antitumor activity.
T36310	AKT-IN-6	1430056-54-4	98.83%
T36310	AKT-IN-6 (INCB-047775) has an inhibitory effect on ATK. Akt is an important component of cellular signaling for growth factors, cytokines, and other cell stimuli...
T6285	GSK-690693	937174-76-0	98.78%
T6285	GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.
T3346	AKT inhibitor VIII	612847-09-3	98.77%
T3346	AKT inhibitor VIII (AKTi-1/2) is a highly specific Akt1/2 inhibitor (IC50: 58/210 nM). The selectivity for Akt1 is higher about 36-fold than Akt3.
T5736	1,3-Dicaffeoylquinic acid	19870-46-3	98.68%
T5736	1,3-Dicaffeoylquinic acid (CYNARIN) is a natural product. It shows antioxidant and choleretic properties and is a potential immunosuppressive agent.