T20029 |
Buformin hydrochloride
|
1190-53-0
|
97.83%
|
|
Buformin hydrochloride (NSC-528218) is a potent AMPK activator,an oral antidiabetic drug of the biguanide class. Buformin delays the absorption of glucose from t...
|
T9010 |
IMM-H007
|
1221412-23-2
|
97.73%
|
|
IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression
|
TN1702 |
Glycycoumarin
|
94805-82-0
|
97.64%
|
|
Glycycoumarin is an estrogen agonist, it shows moderate inhibitory effects against CYP1A2 and CYP2B6.
|
T60128 |
N,N-Didesethyl Sunitinib Hydrochloride
|
873077-70-4
|
97.1%
|
|
N,N-Didesethyl Sunitinib Hydrochloride is a potent AMPK inhibitor with IC50 of 393 nM and 141 nM for AMPKα1 and AMPK2,respectively.
|
T24626 |
PF-249
|
1467059-70-6
|
97.02%
|
|
PF-249 (PF-06685249) is a β1-selective AMPK with an EC50 of 12 nM for AMPK α1β1γ1 and can be used in studies about diabetic nephropathy.
|
TN2097 |
Pomolic acid
|
13849-91-7
|
96.84%
|
|
Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-mediat...
|
T60122 |
Aldometanib
|
2904601-67-6
|
100%
|
|
Aldometanib (LXY-05-029) is an orally active aldolase inhibitor. Aldometanib prevents FBP from binding to v-ATPase-associated aldolase and activates lysosomal AM...
|
T73350 |
BAY-3827
|
2377576-35-5
|
100%
|
|
BAY-3827 is a potent and selective AMPK inhibitor with potential antitumor activity, showing antiproliferative activity in an androgen-dependent prostate cancer ...
|
T6291 |
WZ4003
|
1214265-58-3
|
100%
|
|
WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively. It is no significant inhibition on 139 othe...
|
TP2312 |
MOTS-c(Human) Acetate(1627580-64-6 free)
|
TP2312
|
100%
|
|
MOTS-c(Human) Acetate is a mitochondrial-derived peptide. MOTS-c(human) acetate induces the accumulation of AMP analog AICAR, increases activation of AMPK and ex...
|
T10789 |
Chitosan oligosaccharide
|
148411-57-8
|
|
|
Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine. It has the ability to activate AMPK and simultaneously inhibit inflammatory signal...
|
T2978 |
Mogroside V
|
88901-36-4
|
|
|
Mogroside V is a widely used sweetener, has in vitro AMPK activating effect, it also has anti-inflammatory potential in murine macrophages and a murine ear edema...
|
TN6751 |
1-HEXACOSANOL
|
506-52-5
|
|
|
Hexacosanol activates AMPK and hepatic autophagy and inhibits SREBP2, resulting in hypocholesterolemic activities and improvement of hepatic steatosis.
|
T2750 |
Ginkgolide C
|
15291-76-6
|
|
|
Ginkgolide C (BN-52022), a natural product, can enhance the cardiac function of rats in the body.
|
T7362 |
O-304
|
1261289-04-6
|
|
|
O-304 is a pan-activator of AMP-activated protein kinase (AMPK).
|
T60675L |
AMPK activator 2 hydrochloride( 2410961-69-0 Free base)
|
|
98%
|
|
AMPK activator 2 hydrochloride is a fluoroguanidine-containing derivative that up-regulates the AMPK signaling pathway and down-regulates mTOR/4EBP1/p70S6K.AMPK ...
|
T41162 |
ZLN 024 hydrochloride
|
1883548-91-1
|
98%
|
|
ZLN 024 hydrochloride is an AMPK allosteric activator and stimulates the inactive α1 subunit truncations α1 (1-394) and α1 (1-335) but not α1 (1-312).
|
T73712 |
Metformin-d6 hydrochloride
|
1185166-01-1
|
98%
|
|
Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuterated form of Metformin that can be used to study Metformin metabolism in vivo, and is often us...
|
T14149 |
AICAR phosphate
|
681006-28-0
|
98%
|
|
AICAR phosphate (Acadesine phosphate) is an AMPK activator and inhibitor of autophagy, YAP, and mitophagy, as well as an adenosine analog that regulates glucose ...
|
T13173 |
TMPA
|
1258275-73-8
|
98%
|
|
TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist.
|