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AChR

An acetylcholine receptor (abbreviated AChR) is an integral membrane protein that responds to the binding of acetylcholine, a neurotransmitter.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T23146 PHA 568487 free base 527680-56-4 99%
PHA 568487 free base
The quinuclidine PHA 568487 free base is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated wi...
T5S2361 Epiberberine 6873-09-2 98.95%
Epiberberine
1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/...
T12531 PQCA 1144504-35-7 98.95%
PQCA
PQCA is a muscarinic M1 receptor-positive allosteric regulator, which is highly selective and effective. PQCA exhibited EC50 values of 49 nM in rhesus monkey and...
T23071 Nitrocaramiphen hydrochloride 98636-73-8 98.94%
Nitrocaramiphen hydrochloride
M1 muscarinic antagonist
T25538 Iperoxo 247079-84-1 98.93%
Iperoxo
Iperoxo (Iperoxo iodide) is an agonist of Muscarinic AChR and can be used to probe activation-related conformational transitions of muscarinic receptors.
T13241 UB 165 fumarate 2454492-43-2 98.91%
UB 165 fumarate
UB 165 fumarate is an agonist of the nAChR, a partial agonist of the α4β2 subtype, and a full agonist of the α3β2 subtype, with a Ki value of 0.27 nM for binding...
T72038 YM-58790 168830-70-4 98.88%
YM-58790
YM-58790 free base is a potent mAChR antagonist.YM-58790 free base inhibited M1 mAChR, M2 mAChR, and M3 mAChR with Ki values of 28 nM, 260 nM, and 15 nM, respect...
T1474 Otilonium bromide 26095-59-0 98.88%
Otilonium bromide
Otilonium bromide (SP63) , an antimuscarinic, is utilized as a spasmolytic agent.
T9771 Velufenacin 1648737-78-3 98.88%
Velufenacin
Velufenacin is an antagonist of muscarinic receptor[1].
T10732 Tematropium 113932-41-5 98.87%
Tematropium
Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.
T1202 Cotinine 486-56-6 98.86%
Cotinine
Cotinine (NIH-10498) is an alkaloid found in tobacco and is also the predominant metabolite of nicotine.
T8551 Nitrobenzylthioinosine 38048-32-7 98.83%
Nitrobenzylthioinosine
Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.
T12679 (Rac)-VU 6008667 2092917-63-8 98.83%
(Rac)-VU 6008667
(Rac)-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) with IC50 of 1.8 μM and pIC50 of 5.75, has ...
T28199 NS9283 913830-15-6 98.81%
NS9283
NS9283 is a positive allosteric modulator of α4β2 receptor.
T2172 SQ22536 17318-31-9 98.8%
SQ22536
SQ22536 (9-(tetrahydrofuran-2-yl)-9h-purin-6-amine) , the adenosine analogue 9-(Tetrahydro-2-furyl)adenine, inhibited adenylate cyclase activity of crude membran...
T7895 Syn-Ake acetate 823202-99-9 98.79%
Syn-Ake acetate
Syn-Ake acetate (Dipeptide diaminobutyroyl benzylamide) is a muscarinic acetylcholine receptor antagonist.
T27404 GAT107 1476807-74-5 98.76%
GAT107
GAT107 is a novel and potent α7 nicotinic cholinergic receptor modifier agonist and modulator with anti-inflammatory activity that reverses injury perception in ...
T12339 Oxotremorine M iodide 3854-04-4 98.75%
Oxotremorine M iodide
Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.
T7955 EB-3D 1839150-63-8 98.75%
EB-3D
EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.
T2285 Encenicline hydrochloride 550999-74-1 98.73%
Encenicline hydrochloride
Encenicline hydrochloride (EVP-6124 hydrochloride) is a new-type partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).
PHA 568487 free base
T23146
The quinuclidine PHA 568487 free base is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated wi...
Epiberberine
T5S2361
1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/...
PQCA
T12531
PQCA is a muscarinic M1 receptor-positive allosteric regulator, which is highly selective and effective. PQCA exhibited EC50 values of 49 nM in rhesus monkey and...
Nitrocaramiphen hydrochloride
T23071
M1 muscarinic antagonist
Iperoxo
T25538
Iperoxo (Iperoxo iodide) is an agonist of Muscarinic AChR and can be used to probe activation-related conformational transitions of muscarinic receptors.
UB 165 fumarate
T13241
UB 165 fumarate is an agonist of the nAChR, a partial agonist of the α4β2 subtype, and a full agonist of the α3β2 subtype, with a Ki value of 0.27 nM for binding...
YM-58790
T72038
YM-58790 free base is a potent mAChR antagonist.YM-58790 free base inhibited M1 mAChR, M2 mAChR, and M3 mAChR with Ki values of 28 nM, 260 nM, and 15 nM, respect...
Otilonium bromide
T1474
Otilonium bromide (SP63) , an antimuscarinic, is utilized as a spasmolytic agent.
Velufenacin
T9771
Velufenacin is an antagonist of muscarinic receptor[1].
Tematropium
T10732
Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.
Cotinine
T1202
Cotinine (NIH-10498) is an alkaloid found in tobacco and is also the predominant metabolite of nicotine.
Nitrobenzylthioinosine
T8551
Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.
(Rac)-VU 6008667
T12679
(Rac)-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) with IC50 of 1.8 μM and pIC50 of 5.75, has ...
NS9283
T28199
NS9283 is a positive allosteric modulator of α4β2 receptor.
SQ22536
T2172
SQ22536 (9-(tetrahydrofuran-2-yl)-9h-purin-6-amine) , the adenosine analogue 9-(Tetrahydro-2-furyl)adenine, inhibited adenylate cyclase activity of crude membran...
Syn-Ake acetate
T7895
Syn-Ake acetate (Dipeptide diaminobutyroyl benzylamide) is a muscarinic acetylcholine receptor antagonist.
GAT107
T27404
GAT107 is a novel and potent α7 nicotinic cholinergic receptor modifier agonist and modulator with anti-inflammatory activity that reverses injury perception in ...
Oxotremorine M iodide
T12339
Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.
EB-3D
T7955
EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.
Encenicline hydrochloride
T2285
Encenicline hydrochloride (EVP-6124 hydrochloride) is a new-type partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).
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TargetMol