T23146 |
PHA 568487 free base
|
527680-56-4
|
99%
|
|
The quinuclidine PHA 568487 free base is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated wi...
|
T5S2361 |
Epiberberine
|
6873-09-2
|
98.95%
|
|
1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/...
|
T12531 |
PQCA
|
1144504-35-7
|
98.95%
|
|
PQCA is a muscarinic M1 receptor-positive allosteric regulator, which is highly selective and effective. PQCA exhibited EC50 values of 49 nM in rhesus monkey and...
|
T23071 |
Nitrocaramiphen hydrochloride
|
98636-73-8
|
98.94%
|
|
M1 muscarinic antagonist
|
T25538 |
Iperoxo
|
247079-84-1
|
98.93%
|
|
Iperoxo (Iperoxo iodide) is an agonist of Muscarinic AChR and can be used to probe activation-related conformational transitions of muscarinic receptors.
|
T13241 |
UB 165 fumarate
|
2454492-43-2
|
98.91%
|
|
UB 165 fumarate is an agonist of the nAChR, a partial agonist of the α4β2 subtype, and a full agonist of the α3β2 subtype, with a Ki value of 0.27 nM for binding...
|
T72038 |
YM-58790
|
168830-70-4
|
98.88%
|
|
YM-58790 free base is a potent mAChR antagonist.YM-58790 free base inhibited M1 mAChR, M2 mAChR, and M3 mAChR with Ki values of 28 nM, 260 nM, and 15 nM, respect...
|
T1474 |
Otilonium bromide
|
26095-59-0
|
98.88%
|
|
Otilonium bromide (SP63) , an antimuscarinic, is utilized as a spasmolytic agent.
|
T9771 |
Velufenacin
|
1648737-78-3
|
98.88%
|
|
Velufenacin is an antagonist of muscarinic receptor[1].
|
T10732 |
Tematropium
|
113932-41-5
|
98.87%
|
|
Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.
|
T1202 |
Cotinine
|
486-56-6
|
98.86%
|
|
Cotinine (NIH-10498) is an alkaloid found in tobacco and is also the predominant metabolite of nicotine.
|
T8551 |
Nitrobenzylthioinosine
|
38048-32-7
|
98.83%
|
|
Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.
|
T12679 |
(Rac)-VU 6008667
|
2092917-63-8
|
98.83%
|
|
(Rac)-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) with IC50 of 1.8 μM and pIC50 of 5.75, has ...
|
T28199 |
NS9283
|
913830-15-6
|
98.81%
|
|
NS9283 is a positive allosteric modulator of α4β2 receptor.
|
T2172 |
SQ22536
|
17318-31-9
|
98.8%
|
|
SQ22536 (9-(tetrahydrofuran-2-yl)-9h-purin-6-amine) , the adenosine analogue 9-(Tetrahydro-2-furyl)adenine, inhibited adenylate cyclase activity of crude membran...
|
T7895 |
Syn-Ake acetate
|
823202-99-9
|
98.79%
|
|
Syn-Ake acetate (Dipeptide diaminobutyroyl benzylamide) is a muscarinic acetylcholine receptor antagonist.
|
T27404 |
GAT107
|
1476807-74-5
|
98.76%
|
|
GAT107 is a novel and potent α7 nicotinic cholinergic receptor modifier agonist and modulator with anti-inflammatory activity that reverses injury perception in ...
|
T12339 |
Oxotremorine M iodide
|
3854-04-4
|
98.75%
|
|
Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.
|
T7955 |
EB-3D
|
1839150-63-8
|
98.75%
|
|
EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.
|
T2285 |
Encenicline hydrochloride
|
550999-74-1
|
98.73%
|
|
Encenicline hydrochloride (EVP-6124 hydrochloride) is a new-type partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).
|