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AChR

An acetylcholine receptor (abbreviated AChR) is an integral membrane protein that responds to the binding of acetylcholine, a neurotransmitter.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T0086 Galanthamine hydrobromide 1953-04-4 99.19%
Galanthamine hydrobromide
Galanthamine hydrobromide (Galantamine hydrobromide), a long-acting and centrally active AChE inhibitor (IC50:410 nM), is an allosteric potentiator at neuronal n...
T1341 Nortropine 538-09-0 99.18%
Nortropine
Nortropine (Nortropenol) is used as muscarinic receptor antagonists.
T1049 Oxybutynin chloride 1508-65-2 99.17%
Oxybutynin chloride
Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties. It competitively antagonizes the M1, M2, ...
T23469 TQS 353483-92-8 99.16%
TQS
TQS (4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) is a positive allosteric modulator of α7 nACh receptors.
T0074L Chlorprothixene hydrochloride 6469-93-8 99.16%
Chlorprothixene hydrochloride
Chlorprothixene hydrochloride (Truxal hydrochloride) brings strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrener...
T10630 BuChE-IN-TM-10 2313524-95-5 99.16%
BuChE-IN-TM-10
BuChE-IN-TM-10 (TM-10) is a potent inhibitor of butyrylcholinesterase (BuChE), exhibiting an IC50 of 8.9 nM. It effectively inhibits and disaggregates self-induc...
T0464 Carbetapentane citrate 23142-01-0 99.15%
Carbetapentane citrate
Carbetapentane citrate (Pentoxyverine citrate) , an antitussive (cough suppressant), is frequently used for a cough related to illnesses like the common cold.
T1220 Ethidium bromide 1239-45-8 99.14%
Ethidium bromide
Ethidium bromide (EB) A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several ...
T0962 L-Hyoscyamine 101-31-5 99.12%
L-Hyoscyamine
L-Hyoscyamine (Daturine) functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities of acety...
T0445 Promethazine 60-87-7 99.11%
Promethazine
Promethazine (Proazamine) is an analogue of anti-glaucoma prostaglandin (PG) .
T12489 Pimethixene 314-03-4 99.1%
Pimethixene
Pimethixene (Calmixen) is a highly potent 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors antagonist...
T3993 BQCA 338747-41-4 99.09%
BQCA
BQCA (benzylquinolone carboxylic acid) a highly selective allosteric M1 mAChR modulator.
T27931 LY2033298 886047-13-8 99.06%
LY2033298
LY2033298, a positive allosteric modulator of muscarine M4 receptor, enhances the inhibitory effect of oximoline on light-induced phase shift in circadian activi...
T4986 Imidafenacin 170105-16-5 99.05%
Imidafenacin
Imidafenacin (KRP-197)(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM.
T1401 Meclofenoxate hydrochloride 3685-84-5 99.04%
Meclofenoxate hydrochloride
Meclofenoxate hydrochloride (Lucidril) is an ester of DIMETHYLAMINOETHANOL and para-chlorophenoxyacetic acid. It has been shown to improve memory and general cog...
T68135L (Rac)-Sabcomeline HCl 133642-67-8 99.03%
(Rac)-Sabcomeline  HCl
Sabcomeline HCl is an M1 receptor agonist that can be used to study Alzheimer's disease.
T9877 Tiquizium 149755-23-7 99.02%
Tiquizium
Tiquizium has effective Antimuscarinic effect, and causes significant bronchodilation in patients with chronic obstructive pulmonary disease.
T6707 Tiotropium Bromide hydrate 411207-31-3 99.02%
Tiotropium Bromide hydrate
Tiotropium Bromide hydrate (BA-679 BR hydrate) is a potent anticholinergic and bronchodilator, serving as a muscarinic receptor antagonist, specifically targetin...
T7422 CCMI 917837-54-8 99%
CCMI
CCMI (AVL-3288) is a potent and selective modulator of α7 nAChR-positive allosteric.
T0716 Molindone hydrochloride 15622-65-8 99%
Molindone hydrochloride
Molindone hydrochloride (EN-1733A) is an indole derivative effective in schizophrenia and other psychoses by blocking the effects of dopamine in the brain.
Galanthamine hydrobromide
T0086
Galanthamine hydrobromide (Galantamine hydrobromide), a long-acting and centrally active AChE inhibitor (IC50:410 nM), is an allosteric potentiator at neuronal n...
Nortropine
T1341
Nortropine (Nortropenol) is used as muscarinic receptor antagonists.
Oxybutynin chloride
T1049
Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties. It competitively antagonizes the M1, M2, ...
TQS
T23469
TQS (4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) is a positive allosteric modulator of α7 nACh receptors.
Chlorprothixene hydrochloride
T0074L
Chlorprothixene hydrochloride (Truxal hydrochloride) brings strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrener...
BuChE-IN-TM-10
T10630
BuChE-IN-TM-10 (TM-10) is a potent inhibitor of butyrylcholinesterase (BuChE), exhibiting an IC50 of 8.9 nM. It effectively inhibits and disaggregates self-induc...
Carbetapentane citrate
T0464
Carbetapentane citrate (Pentoxyverine citrate) , an antitussive (cough suppressant), is frequently used for a cough related to illnesses like the common cold.
Ethidium bromide
T1220
Ethidium bromide (EB) A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several ...
L-Hyoscyamine
T0962
L-Hyoscyamine (Daturine) functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities of acety...
Promethazine
T0445
Promethazine (Proazamine) is an analogue of anti-glaucoma prostaglandin (PG) .
Pimethixene
T12489
Pimethixene (Calmixen) is a highly potent 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors antagonist...
BQCA
T3993
BQCA (benzylquinolone carboxylic acid) a highly selective allosteric M1 mAChR modulator.
LY2033298
T27931
LY2033298, a positive allosteric modulator of muscarine M4 receptor, enhances the inhibitory effect of oximoline on light-induced phase shift in circadian activi...
Imidafenacin
T4986
Imidafenacin (KRP-197)(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM.
Meclofenoxate hydrochloride
T1401
Meclofenoxate hydrochloride (Lucidril) is an ester of DIMETHYLAMINOETHANOL and para-chlorophenoxyacetic acid. It has been shown to improve memory and general cog...
(Rac)-Sabcomeline HCl
T68135L
Sabcomeline HCl is an M1 receptor agonist that can be used to study Alzheimer's disease.
Tiquizium
T9877
Tiquizium has effective Antimuscarinic effect, and causes significant bronchodilation in patients with chronic obstructive pulmonary disease.
Tiotropium Bromide hydrate
T6707
Tiotropium Bromide hydrate (BA-679 BR hydrate) is a potent anticholinergic and bronchodilator, serving as a muscarinic receptor antagonist, specifically targetin...
CCMI
T7422
CCMI (AVL-3288) is a potent and selective modulator of α7 nAChR-positive allosteric.
Molindone hydrochloride
T0716
Molindone hydrochloride (EN-1733A) is an indole derivative effective in schizophrenia and other psychoses by blocking the effects of dopamine in the brain.
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TargetMol