5-HT Receptor

5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission.

Cat. No.	Product name	CAS No.	Purity
TQ0315	Tandospirone	87760-53-0	98%
TQ0315	Tandospirone (SM-3997) is a selective partial agonist of 5-HT1A receptor (Ki: 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Kis...
T12262	NPS ALX Compound 4a	299433-10-6	98%
T12262	NPS ALX Compound 4a is a potent and selective antagonist of 5-HT6 receptor (IC50 of 7.2 nM)
T4375	Methiothepin maleate	19728-88-2	98%
T4375	Methiothepin maleate (Metitepine) is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors.
T10075L2	2-Methyl-5-HT hydrochloride	845861-49-6	98%
T10075L2	2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.
T12842	SB-269970	201038-74-6	98%
T12842	SB-269970 is a antagonist of 5-HT7 receptor(pKi of 8.3).
TN4092	Galanolactone	115753-79-2	98%
TN4092	Galanolactone has anti-5-HT effect, a diterpenoid isolated from ginger, is related to antagonism of 5-HT3 receptors, it has inhibit nitric oxide production with ...
T11302	Flumexadol	30914-89-7	98%
T11302	Flumexadol is a selective and affinity 5-HT2C receptor agonist with a Ki of 25 nM for the (+)-enantiomer of Flumexadol, and is 40-fold selective over the 5-HT2A ...
T12865	SCH-23390 maleate	87134-87-0	98%
T12865	SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM, r...
TN3235	7-Hydroxycadalene	2102-75-2	98%
TN3235	7-Hydroxycadalene shows cytotoxicity activity against HCT-15 cell line with IC50 18.89 ± 1.2 uM.
T11293	(±)-Fabesetron hydrochloride	129299-81-6	98%
T11293	FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.
T10075L	2-Methyl-5-HT maleate	78263-91-9	98%
T10075L	2-Methyl-5-HT maleate (2-Methyl-5-hydroxytryptamine maleate) is a potent and selective 5-HT3 receptor agonist, which is shown to display anti-depressive-like eff...
T10371	Arotinolol	68377-92-4	98%
T10371	Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radiol...
T22296	Cisapride hydrate	260779-88-2	98%
T22296	Cisapride acts directly as a selective agonist of serotonin 5-HT4 receptor with IC50 value of 0.483 μM. And It also acts indirectly as a parasympathomimetic.
T12899L	SEP-363856 hydrochloride	1310422-41-3	99.99%
T12899L	SEP-363856 hydrochloride (SEP-856 hydrochloride) is an agent of orally active and CNS active psychotropic with a unique, non-D2/5-HT2A mechanism of action, exert...
T24885L	Tiaspirone hydrochloride	87691-92-7	99.98%
T24885L	Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity. Tiaspirone hydrochloride influences the electrophysiological activity of dopa...
T1619	Trazodone hydrochloride	25332-39-2	99.98%
T1619	Trazodone hydrochloride (Trazodone HCl) is a serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients wi...
T21629	Loxapine	1977-10-2	99.98%
T21629	Loxapine is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent,used primarily in the treatment of schizo...
T1509	Cyclobenzaprine hydrochloride	6202-23-9	99.98%
T1509	Cyclobenzaprine hydrochloride (MK130 hydrochloride) , a centrally acting muscle relaxant with antidepressant activity, leads to a reduction in muscle spasms.
T0204	Protriptyline hydrochloride	1225-55-4	99.98%
T0204	Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline, a tricyclic secondary amine with an antidepressant property. Protriptyline hydrochlo...
T3648	Hypidone hydrochloride	1339058-04-6	99.97%
T3648	Hypidone hydrochloride (YL0919) is a novel antidepressant candidate with dual activity as a 5-HT1A receptor agonist and a selective serotonin reuptake inhibitor....