Home Tools
Log in
Cart

Search Result

Search Results for " vemurafenib "

Targets

7

Compounds

1

Libraries

Cat No. Product Name Synonyms Targets
T2382 Vemurafenib RO5185426,RG7204,PLX4032 Raf , MAPK , ACK , Src , Autophagy
Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently. Vemurafenib exhibits antitumor activity and is used for the treatment of BRAF V600E mutation-positive...
T8654 Plx-4032 Vemurafenib Raf
Plx-4032 (Vemurafenib) is a small-molecule B-Raf inhibitor for the potential treatment of malignant melanoma.
T27537 Hexafluoro
Hexafluoro is an inhibitor of DRP1 phosphorylation. Honokiol DCA stimulates a phenotype suggestive of respiration through mitochondrial normalization and demonstrates activity in Vemurafenib-resistant melanoma in vivo.
T27551 Honokiol DCA Honokiol Bis-Dichloroacetate
Honokiol DCA is an inhibitor of DRP1 phosphorylation. Honokiol DCA stimulates a phenotype suggestive of respiration through mitochondrial normalization and demonstrating activity in Vemurafenib-resistant melanoma in vivo...
T70424 EBI-907
EBI-907 is a highly potent and orally efficacious B-RafV600E inhibitor. EBI-907 displays a low single-digit nanomolar activity (IC50 = 4.9 nM), which is >10-fold more potent than Vemurafenib (IC50 = 59 nM). EBI-907 also...
T78777 Vem-L-Cy5 Raf
Vem-L-Cy5 (compound 3), a Vemurafenib-based BRAF inhibitor conjugated with the near-infrared (NIR) fluorophore cyanine-5 (Cy5), selectively targets the BRAF V600E mutation and inhibits MEK phosphorylation. This compound ...
T63210 Everafenib
Everafenib is a potent BRAF inhibitor that crosses the blood-brain barrier and also inhibits the MAPK pathway. Everafenib inhibits the activity of a range of V600EBRAF melanoma cell lines (IC50: 2-10 nM) and is more effe...
Cat No. Product Name
L8800 Drug-Fragment Library

1158 compounds
1158 drug fragments,a must-have tool for FBDD;
TargetMol