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Search Results for " sars-cov2 "

Targets

7

Compounds

1

Natural Products

Cat No. Product Name Synonyms Targets
T9705 TL-895 BTK
TL-895 is an ATP-competitive, and highly selective irreversible inhibitor of Bruton’s Tyrosine Kinase(BTK). TL-895 showed good potency with an IC50 of 1.5 nM and a Ki of 11.9 nM.
T15271 Denifanstat FASN-IN-2,TVB2640,TVB-2640 Fatty Acid Synthase
Denifanstat (FASN-IN-2) is a Fatty Acid Synthase (FASN) inhibitor(IC50 of 0.052 μM and an EC50 of 0.072 μM),with potential antineoplastic activity.
T62089 FWM-1
FWM-1 is a potent inhibitor of SARS-COV-2 NSP13 resolvase (free energy of binding: -328.6 kcal/mol).FWM-1 shows effective disruption of the binding of ATP to SARS-COV2 resolvase.
T72446 SARS-CoV-2 Mpro-IN-4
SARS-CoV-2 Mpro-IN-4 is a dual inhibitor targeting Main Protease (M Pro) and Cathepsin L (CatL), exhibiting inhibition concentrations (IC50) of 900 nM and 60 nM, respectively. It demonstrates antiviral activity by effect...
T76999 Cilgavimab
Cilgavimab (AZD-1061; COV2-2130), a humanized SARS-CoV-2-neutralizing monoclonal antibody, forms part of the monoclonal antibody combination AZD7442 with Tixagevimab. It demonstrates protective effects in mouse models of...
T72447 SARS-CoV-2 Mpro-IN-5
SARS-CoV-2 Mpro-IN-5 is a dual inhibitor targeting Main Protease (M Pro) and Cathepsin L (CatL) with IC50 values of 1800 nM and 145 nM, respectively. This compound demonstrates antiviral activity by inhibiting SARS-CoV-2...
T70929 Naldemedine tosylate S-297995 tosylate
Naldemedine tosylate (S-297995) is an orally active μ-opioid receptor antagonist (PAMORA) with high binding affinities (K_i = 0.34, 0.43, 0.94 nM) and potent antagonist activities (IC_50 = 25.57, 7.09, 16.1 nM) towards h...
Cat No. Product Name Synonyms Targets
T75273 Teicoplanin sodium
Teicoplanin sodium (Antibiotic MDL-507 sodium) is a potent lipoglycopeptide antibiotic . Teicoplanin sodium shows antiviral activity for HIV-1 , SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity [1] [2...
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