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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15579 | INDY | 1-(3-ethyl-5-hydroxy-1,3-benzothiazol-2-ylidene)propan-2-one | DYRK |
INDY is an ATP-competitive inhibitor of Dyrk1A and Dyrk1B with IC50s of 0.24 μM and 0.23 μM and a Ki of 0.18 μM for Dyrk1A ATP pocket, respectively. | |||
T23186 | ProINDY | Pro-indy | DYRK |
ProINDY (Pro-indy) is a potent DYRK inhibitor that activates NFAT for the study of Down syndrome. | |||
T73551 | FINDY | ||
FINDY is a folding intermediate-selective inhibitor of DYRK1A . FINDY can inhibit Ser97 autophosphorylation with an IC 50 value of 35 μM. FINDY can be used for the research of neurological disorder . |