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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6084 | Rabusertib | LY2603618,IC-83 | Chk , PDK , Autophagy |
Rabusertib (IC-83) is an inhibitor of the cell cycle checkpoint kinase 1 (chk1) with potential chemopotentiating activity. Rabusertib has been used in trials studying the treatment of Cancer, Solid Tumors, Advanced Cance... | |||
T10442 | A 83-01 sodium salt | ALK | |
A 83-01 sodium salt is a potent inhibitor of TGF-β type I receptor ALK5 kinase, ALK4 and ALK7, with IC 50 s of 12 nM, 45 nM and 7.5 nM against the ALK5, ALK4 and ALK7 induced transcription, respectively [1]. |