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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14921 | CE-245677 | Tie-2 , Trk receptor | |
CE-245677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases. With a cellular IC50s of 4.7 and 1 nM. | |||
T68286 | CE-245677 mesylate | ||
CE-245677 is a selective, orally active Tie2 kinase inhibitor identified by Pfizer previously in development for the treatment of certain cancers. CE-245,677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases w... |