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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6357 | (S)-crizotinib | ent-crizotinib | Apoptosis , DNA/RNA Synthesis , MTH1 |
(S)-crizotinib (ent-crizotinib) (IC50 of 72 nM), an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib. | |||
T1661 | Crizotinib | PF-02341066 | c-Met/HGFR , ROS , ALK , Autophagy , ROS Kinase |
Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor. | |||
T8399 | Crizotinib hydrochloride | PF-02341066 hydrochloride | c-Met/HGFR , ROS , ALK , Autophagy , ROS Kinase |
Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM) | |||
T1661L | Crizotinib acetate | PF02341066,PF-2341066,PF 02341066,PF-02341066,PF2341066 | |
Crizotinib, an orally bioavailable agent, belongs to the class of c-met/hepatocyte growth factor receptor (HGFR) tyrosine kinase inhibitors with potential antineoplastic activity. |