T7102 |
BCTC
|
393514-24-4
|
98%
|
|
BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 (IC50 of 35 and 6 nM, respectively)
|
T7189 |
AMG9810
|
545395-94-6
|
98%
|
|
AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid receptor 1 (TRPV1) (IC50s = 24.5 and 85.6 nM for human and rat TRPV1, respectively)...
|
T6660 |
SB-705498
|
501951-42-4
|
98%
|
|
SB705498 is a TRPV1 antagonist for hTRPV1. SB-705498 has been investigated for the treatment of Rhinitis, Chronic Cough, and Non-allergic Rhinitis.
|
T6530 |
HC-030031
|
349085-38-7
|
98%
|
|
HC-030031 (TOSLAB 829227) is a potent TRPA1 inhibitor, which antagonizes AITC- and formalin-evoked calcium influx with IC50s of 6.2±0.2 and 5.3±0.2 μM, respectiv...
|
T5962 |
TRPM8 antagonist WS-3
|
39711-79-0
|
98%
|
|
TRPM8 antagonist WS-3 (Cyclohexanecarboxamide) is an agonist of TRPM8( EC50 : 3.7 μM).
|
T5698 |
TRPM8 antagonist 2
|
259674-19-6
|
98%
|
|
TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM. TRPM8 antagonist 2 is used in the research of neuropathic pain syndromes.
|
T7191 |
Diphenyleneiodonium chloride
|
4673-26-1
|
98%
|
|
Diphenyleneiodonium chloride (DPI)(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 μM, respectively),and displays broad-spectrum...
|
T64337 |
PF-04745637
|
1917294-46-2
|
97.91%
|
|
PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].
|
T1814 |
ICILIN
|
36945-98-9
|
97.61%
|
|
ICILIN (AG-3-5) is a synthetic TRPM8 ion channel super-agonist.
|
T1321 |
Nonivamide
|
2444-46-4
|
97.61%
|
|
Nonivamide (Nonanoic acid vanillylamide) is found in herbs and spices. Nonivamide is an alkaloid from Capsicum species Nonivamide is a flavoring ingredient. Noni...
|
TQ0001 |
1,4-Cineole
|
470-67-7
|
97.15%
|
|
1,4-Cineole (Isocineole) is a natural, oxygenated monoterpene. 1,4-Cineole can activate both human TRPM8 and human TRPA1.
|
T77645 |
JC-229
|
|
97.14%
|
|
JC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. JC-229 can be used to study human African Trypanosomiasis (HAT).
|
T15465 |
HC-070
|
1628291-95-1
|
97.06%
|
|
HC-070 is a TRPC5 and TRPC4 antagonist (IC50 = 9.3 nM and 46 nM).
|
T9776 |
TRPM4 inhibitor 8
|
1353979-43-7
|
97%
|
|
TRPM4 inhibitor 8 is an inhibitor of Transient receptor potential melastatin 4(TRPM4) which contributes to viability, migration, cell cycle shift, and adhesion.
|
T6848 |
GSK1016790A
|
942206-85-1
|
96.25%
|
|
GSK1016790A (GSK101) (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34 nM in choroid plexus epithelial ce...
|
TN2429 |
Capsiate
|
205687-01-0
|
96.24%
|
|
Capsiate is an orally active TRPV1 agonist, a non-irritating capsaicin analog that acts as an antiallergic agent with anti-inflammatory, antioxidant, hypoglycemi...
|
T3865 |
Beta-Eudesmol
|
473-15-4
|
95.62%
|
|
beta-Eudesmol (Beta-Selinenol) is a noncompetitive antagonist of nicotinic acetylcholine receptors (nAChRs). It is a sesquiterpene that has been found in a varie...
|
T23106 |
Olvanil
|
58493-49-5
|
95.06%
|
|
Olvanil (N-Vannilyloleoylamide) is a vanilloid receptor agonist with EC50 of 0.7nM.
|
T22124 |
Oleoyl Serotonin
|
1002100-44-8
|
100.00%
|
|
Oleoyl Serotonin is an antagonist of hTRPV1 with an IC50 of 2.57 μM.
|
T77723 |
RN-1665
|
1803003-65-7
|
100%
|
|
RN-1665 is a potent and selective TRPV4 receptor antagonist.
|