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Sodium Channel

Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T4550 Ajmaline 4360-12-7 98.19%
Ajmaline
Ajmaline (Cardiorythmine) is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or v...
T2391 Camostat mesylate 59721-29-8 98.17%
Camostat mesylate
Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.
T7587 Tenapanor 1234423-95-0 98.08%
Tenapanor
Tenapanor (RDX 5791) is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which plays a prominent role in sodium handling in the gastrointestinal tr...
T30249 AZD 7009 335619-18-6 98.08%
AZD 7009
AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM. AZD 7009 inhibited late sodium cur...
T69552 Suzetrigine 2649467-58-1 98.08%
Suzetrigine
Suzetrigine(VX-548) is an orally active and specific NaV1.8 inhibitor. Suzetrigine has analgesic activity and can be used to study acute pain and neurotransmissi...
T13177L Tocainide 41708-72-9 98.04%
Tocainide
Tocainide is a blocker of the sodium channel and used for the treatment of tinnitus.
T12421 PF-04885614 1480833-70-2 98.02%
PF-04885614
PF-04885614 is a potent inhibitor of NaV1.8, has potential for neurological and neurodevelopmental diseases treatment.
T14380 AZD7507 1041852-85-0 98.01%
AZD7507
AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.
T7349 Ralfinamide 133865-88-0 98%
Ralfinamide
Ralfinamide (Priralfinamide) is an orally available Na-channel blocker for the treatment of neuropathic pain and other pain conditions.
T4590 (+)-Kavain 500-64-1 98%
(+)-Kavain
(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.
T0802 Procaine hydrochloride 51-05-8 98%
Procaine hydrochloride
Procaine hydrochloride (Novocaine HCl) is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties....
T0675 Topiramate 97240-79-4 98%
Topiramate
Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associate...
T7182 Metaflumizone 139968-49-3 98%
Metaflumizone
Metaflumizone (BAS-320I) is a sodium channel blocker insecticide.
T7336 ICA-121431 313254-51-2 98%
ICA-121431
ICA-121431 (2,2-Diphenyl-N-[4-(thiazol-2-ylsulfamoyl) is a nanomolar potent small molecule Nav1.7 channel inhibitor with IC50 of 19 nM for rat Nav1.7, with littl...
T23439 TC-N 1752 1211866-85-1 97.87%
TC-N 1752
TC-N 1752 is an orally active inhibitor of Nav1.7 channel with IC50 of 0.17 μM. TC-N 1752 shows analgesic activities.
T6856 Halofuginone 55837-20-2 97.67%
Halofuginone
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml ...
T12219 NHE3-IN-1 632355-68-1 97.44%
NHE3-IN-1
NHE3-IN-1 is a inhibitor of Na+/H+-exchanger 3 (NHE-3).
T2238 Cariporide 159138-80-4 97.41%
Cariporide
Cariporide (HOE-642) (HOE-642), an effective NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-...
T15174 DSP-2230 1233231-30-5 97.31%
DSP-2230
DSP-2230 is a selective blocker of Nav1.7/Nav1.8.
T2024 A-803467 944261-79-4 96.94%
A-803467
A-803467 is a selective NaV1.8 channel blocker.
Ajmaline
T4550
Ajmaline (Cardiorythmine) is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or v...
Camostat mesylate
T2391
Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.
Tenapanor
T7587
Tenapanor (RDX 5791) is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which plays a prominent role in sodium handling in the gastrointestinal tr...
AZD 7009
T30249
AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM. AZD 7009 inhibited late sodium cur...
Suzetrigine
T69552
Suzetrigine(VX-548) is an orally active and specific NaV1.8 inhibitor. Suzetrigine has analgesic activity and can be used to study acute pain and neurotransmissi...
Tocainide
T13177L
Tocainide is a blocker of the sodium channel and used for the treatment of tinnitus.
PF-04885614
T12421
PF-04885614 is a potent inhibitor of NaV1.8, has potential for neurological and neurodevelopmental diseases treatment.
AZD7507
T14380
AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.
Ralfinamide
T7349
Ralfinamide (Priralfinamide) is an orally available Na-channel blocker for the treatment of neuropathic pain and other pain conditions.
(+)-Kavain
T4590
(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.
Procaine hydrochloride
T0802
Procaine hydrochloride (Novocaine HCl) is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties....
Topiramate
T0675
Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associate...
Metaflumizone
T7182
Metaflumizone (BAS-320I) is a sodium channel blocker insecticide.
ICA-121431
T7336
ICA-121431 (2,2-Diphenyl-N-[4-(thiazol-2-ylsulfamoyl) is a nanomolar potent small molecule Nav1.7 channel inhibitor with IC50 of 19 nM for rat Nav1.7, with littl...
TC-N 1752
T23439
TC-N 1752 is an orally active inhibitor of Nav1.7 channel with IC50 of 0.17 μM. TC-N 1752 shows analgesic activities.
Halofuginone
T6856
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml ...
NHE3-IN-1
T12219
NHE3-IN-1 is a inhibitor of Na+/H+-exchanger 3 (NHE-3).
Cariporide
T2238
Cariporide (HOE-642) (HOE-642), an effective NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-...
DSP-2230
T15174
DSP-2230 is a selective blocker of Nav1.7/Nav1.8.
A-803467
T2024
A-803467 is a selective NaV1.8 channel blocker.
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TargetMol