T4550 |
Ajmaline
|
4360-12-7
|
98.19%
|
|
Ajmaline (Cardiorythmine) is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or v...
|
T2391 |
Camostat mesylate
|
59721-29-8
|
98.17%
|
|
Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.
|
T7587 |
Tenapanor
|
1234423-95-0
|
98.08%
|
|
Tenapanor (RDX 5791) is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which plays a prominent role in sodium handling in the gastrointestinal tr...
|
T30249 |
AZD 7009
|
335619-18-6
|
98.08%
|
|
AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM. AZD 7009 inhibited late sodium cur...
|
T69552 |
Suzetrigine
|
2649467-58-1
|
98.08%
|
|
Suzetrigine(VX-548) is an orally active and specific NaV1.8 inhibitor. Suzetrigine has analgesic activity and can be used to study acute pain and neurotransmissi...
|
T13177L |
Tocainide
|
41708-72-9
|
98.04%
|
|
Tocainide is a blocker of the sodium channel and used for the treatment of tinnitus.
|
T12421 |
PF-04885614
|
1480833-70-2
|
98.02%
|
|
PF-04885614 is a potent inhibitor of NaV1.8, has potential for neurological and neurodevelopmental diseases treatment.
|
T14380 |
AZD7507
|
1041852-85-0
|
98.01%
|
|
AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.
|
T7349 |
Ralfinamide
|
133865-88-0
|
98%
|
|
Ralfinamide (Priralfinamide) is an orally available Na-channel blocker for the treatment of neuropathic pain and other pain conditions.
|
T4590 |
(+)-Kavain
|
500-64-1
|
98%
|
|
(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.
|
T0802 |
Procaine hydrochloride
|
51-05-8
|
98%
|
|
Procaine hydrochloride (Novocaine HCl) is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties....
|
T0675 |
Topiramate
|
97240-79-4
|
98%
|
|
Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associate...
|
T7182 |
Metaflumizone
|
139968-49-3
|
98%
|
|
Metaflumizone (BAS-320I) is a sodium channel blocker insecticide.
|
T7336 |
ICA-121431
|
313254-51-2
|
98%
|
|
ICA-121431 (2,2-Diphenyl-N-[4-(thiazol-2-ylsulfamoyl) is a nanomolar potent small molecule Nav1.7 channel inhibitor with IC50 of 19 nM for rat Nav1.7, with littl...
|
T23439 |
TC-N 1752
|
1211866-85-1
|
97.87%
|
|
TC-N 1752 is an orally active inhibitor of Nav1.7 channel with IC50 of 0.17 μM. TC-N 1752 shows analgesic activities.
|
T6856 |
Halofuginone
|
55837-20-2
|
97.67%
|
|
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml ...
|
T12219 |
NHE3-IN-1
|
632355-68-1
|
97.44%
|
|
NHE3-IN-1 is a inhibitor of Na+/H+-exchanger 3 (NHE-3).
|
T2238 |
Cariporide
|
159138-80-4
|
97.41%
|
|
Cariporide (HOE-642) (HOE-642), an effective NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-...
|
T15174 |
DSP-2230
|
1233231-30-5
|
97.31%
|
|
DSP-2230 is a selective blocker of Nav1.7/Nav1.8.
|
T2024 |
A-803467
|
944261-79-4
|
96.94%
|
|
A-803467 is a selective NaV1.8 channel blocker.
|