T80433 |
δ-Buthitoxin-Hj1a
|
|
98%
|
|
δ-Buthitoxin-Hj1a, a scorpion-venom peptide, functions as a potent agonist for the NaV1.1 channel, exhibiting an EC50 value of 17 nM. It can be employed in resea...
|
T80437 |
μ-TRTX-Hd1a
|
|
98%
|
|
μ-TRTX-Hd1a, a spider venom-derived compound, selectively inhibits the human NaV 1.7 channel by functioning as a gating modifier. It interacts with the S3b-S4 pa...
|
T80439 |
GTx1-15
|
|
98%
|
|
GTx1-15, an inhibitor cystine knot (ICK) peptide, antagonizes the voltage-dependent calcium channel Cav3.1, as well as voltage-dependent sodium channels Nav1.3 a...
|
T80440 |
GsAF-I
|
|
98%
|
|
GsAF-I is a potent blocker of Na_v and hERG1 channels, exhibiting half-maximal inhibitory concentrations (IC50s) of 0.36 μM (Na_v 1.1), 0.6 μM (Na_v 1.2), 1.28 μ...
|
T80444 |
Phlo1b
|
|
98%
|
|
Phlo1b (μ-TrTx-Phlo1b), a 35-amino acid peptide toxin, selectively inhibits Nav1.7 channels with minimal inhibition of Nav1.2 and Nav1.5 [1].
|
T80445 |
Phlo1a
|
|
98%
|
|
Phlo1a (μ-TrTx-Phlo1a), a 35-amino acid peptide toxin, demonstrates a weak inhibitory effect on Nav1.2 and Nav1.5 channels [1]. Meanwhile, Phlo1b acts as a selec...
|
T80450 |
Pe1b
|
|
98%
|
|
Pe1b (μ-TrTx-Pe1b) is a selective inhibitor of the NaV1.7 channel, exhibiting an inhibitory concentration 50 (IC50) value of 167 nanomolar (nM) [1].
|
T80451 |
Ceratotoxin-2
|
880885-98-3
|
98%
|
|
Ceratotoxin-2 (CcoTx2) is a voltage-gated sodium channel inhibitor, demonstrating half maximal inhibitory concentrations (IC50) of 8 nM for Na v 1.2/β 1 and 88 n...
|
T80452 |
Ceratotoxin-1
|
|
98%
|
|
Ceratotoxin-1 (CcoTx1) is a peptide toxin that functions as an inhibitor of various voltage-gated sodium channel subtypes. It selectively inhibits Nav1.1/β1, Nav...
|
T80454 |
BmK-M1
|
|
98%
|
|
BmK-M1, a scorpion-derived toxin, consists of a 64-amino acid polypeptide stabilized by four disulfide bridges. This compound functions as an inhibitor of the Na...
|
T80455 |
ω-Conotoxin CVIB
|
325164-09-8
|
98%
|
|
ω-Conotoxin CVIB is an antagonist of non-selective N- and P/Q-type voltage-gated calcium channels (VGCCs). It inhibits depolarization-activated whole-cell VGCC c...
|
T80456 |
BDS-II
|
|
98%
|
|
BDS-II, a peptide toxin comprising 43 amino acids, selectively inhibits the Kv3.4 channel [1].
|
T80461 |
Anthopleurin-C
|
|
98%
|
|
Anthopleurin-C (APE 2-1) is a cardiotonic polypeptide exhibiting a potent positive inotropic effect [1].
|
T80485 |
μ-Conotoxin SxIIIC
|
|
98%
|
|
μ-Conotoxin SxIIIC, an irreversible NaV channel inhibitor, is derived from Conus striolatus and is useful in researching neurological disorders, including chroni...
|
T80488 |
µ-Conotoxin SIIIA
|
877860-32-7
|
98%
|
|
μ-Conotoxin SIIIA, a tetrodotoxin (TTX)-resistant sodium channel blocker, is a toxic peptide derived from Conus snail venom. It has applications in researching n...
|
T80490 |
µ-Conotoxin BuIIIC
|
1400096-08-3
|
98%
|
|
μ-Conotoxin BuIIIC (Mu-Conotoxin BuIIIC) effectively inhibits the NaV1.4 sodium channel [1].
|
T80491 |
µ-Conotoxin BuIIIB
|
1400096-06-1
|
98%
|
|
μ-Conotoxin BuIIIB (Mu-Conotoxin BuIIIB), a selective blocker of mammalian neuronal voltage-gated sodium channels (VGSC), is derived from Cone snail venom and se...
|
T80492 |
Mambalgin-2
|
|
98%
|
|
Mambalgin-2 (Mamb-2), a venom peptide sourced from the African black mamba, acts as an inhibitor of acid-sensitive ion channels (ASICs). It is utilized in resear...
|
T80493 |
µ-Conotoxin BuIIIA
|
|
98%
|
|
μ-Conotoxin BuIIIA (Mu-Conotoxin BuIIIA), a toxin derived from Cone snail venom, functions as a voltage-gated sodium channel (VGSC) blocker. This toxic peptide i...
|
T80494 |
Tap1a
|
|
98%
|
|
Theraphotoxin-Tap1a (Tap1a) is a spider venom-derived peptide that acts as an inhibitor of sodium channels, displaying IC50 values of 80 nM for Na v 1.7 and 301 ...
|