T80169 |
ProTx-III
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98%
|
|
ProTx-III, a spider venom peptide derived from the Peruvian green velvet tarantula, functions as a selective and potent inhibitor of the voltage-gated sodium cha...
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T80176 |
Crotamine
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98%
|
|
Crotamine, a 42 amino acid toxin featuring three disulfide bridges, functions as a Na+ channel modulator with analgesic properties. This compound interacts with ...
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T80177 |
Phlotoxin-1
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98%
|
|
Phlotoxin-1 (PhlTx1), a 34-amino acid peptide featuring three disulfide bridges, is derived from the Phlogiellus genus spider and acts as an antinociceptive agen...
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T80178 |
Dc1a
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98%
|
|
Dc1a, a toxin isolated from the desert bush spider Diguetia canities [1], potently facilitates the opening of the German cockroach Na v channel (BgNa v 1).
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T80179 |
GrTx1
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98%
|
|
GrTx1, a peptide toxin derived from Grammostola rosea spider venom, selectively inhibits sodium channels Nav1.1, Nav1.2, Nav1.3, Nav1.4, Nav1.6, and Nav1.7, with...
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T80181 |
MitTx-alpha
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98%
|
|
MitTx-alpha, a component of the complex MitTx, acts as a powerful and enduring agonist specifically targeting acid-sensing ion channels (ASICs), with a pronounce...
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T80182 |
MitTx
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98%
|
|
MitTx, a complex consisting of MitTx-α and MitTx-β, serves as an ASIC1 channel activator, demonstrating EC50 values of 9.4 nM and 23 nM for the ASIC1a and ASIC1b...
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T80184 |
GsAF-II
|
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98%
|
|
GsAF-II is a peptide toxin that selectively blocks hERG1 subtype potassium channels through a voltage-dependent mechanism and impedes Nav1.x subtype sodium chann...
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T80186 |
Hainantoxin-III
|
1809149-40-3
|
98%
|
|
Jingzhaotoxin-V is a peptide that suppresses potassium currents in Xenopus laevis oocytes, exhibiting an IC50 of 604.2 nM, while concurrently targeting both tetr...
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T80188 |
Hm1a
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|
98%
|
|
Hm1a, a disulfide-rich spider-venom peptide and NaV1.1 activator, reestablishes the function of inhibitory interneurons in a Dravet syndrome (DS) mouse model [1]...
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T80189 |
Hainantoxin-IV
|
651782-02-4
|
98%
|
|
Hainantoxin-IV acts as a specific antagonist for tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels, with His28 and Lys32 being critical residues for b...
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T80230 |
μ-Conotoxin Sx IIIA
|
1400096-00-5
|
98%
|
|
μ-Conotoxin Sx IIIA is a biologically active peptide that functions as a blocker of NaV1.4 channels.
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T80425 |
Jingzhaotoxin-V
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|
98%
|
|
Jingzhaotoxin-V, a 29-residue polypeptide from Chilobrachys jingzhao spider venom, selectively inhibits tetrodotoxin-resistant and tetrodotoxin-sensitive sodium ...
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T80426 |
Jingzhaotoxin-IX
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98%
|
|
Jingzhaotoxin-IX is a C-terminally amidated peptide neurotoxin consisting of 35 amino acid residues. It inhibits both tetrodotoxin-resistant and tetrodotoxin-sen...
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T80427 |
Jingzhaotoxin-II
|
|
98%
|
|
Jingzhaotoxin-II, a neurotoxin composed of 32 amino acid residues featuring two acidic and two basic residues, selectively inhibits voltage-gated sodium channels...
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T80428 |
Jingzhaotoxin-34
|
|
98%
|
|
Jingzhaotoxin-34, a 35-residue neurotoxic polypeptide, selectively inhibits tetrodotoxin-sensitive (TTX-S) sodium currents in rat dorsal root ganglion neurons wi...
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T80429 |
π-TRTX-Hm3a
|
|
98%
|
|
π-TRTX-Hm3a, a 37-amino acid peptide derived from the venom of the Togo starburst tarantula (Heteroscodra maculata), selectively inhibits the acid-sensing ion ch...
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T80430 |
δ-Theraphotoxin-Hm1b
|
|
98%
|
|
δ-Theraphotoxin-Hm1b, a 42-amino acid peptide derived from the Togo starburst tarantula (Heteroscodra maculata) venom, selectively inhibits the inactivation of N...
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T80431 |
δ-Theraphotoxin-Hm1a toxin
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|
98%
|
|
δ-Theraphotoxin-Hm1a is a selective NaV1.1 activator that induces pain and touch sensitivity, with potential applications in irritable bowel syndrome research [1...
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T80432 |
δ-Buthitoxin-Hj2a
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|
98%
|
|
δ-Buthitoxin-Hj2a, a potent scorpion-venom peptide, acts as a NaV1.1 agonist with an EC50 value of 32 nM and is employed in Dravet syndrome (DS) research [1].
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