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Serotonin Transporter

The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that in humans is encoded by the SLC6A4 gene. SERT is a type of monoamine transporter protein that transports serotonin from the synaptic cleft back to the presynaptic neuron.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T0450 Fluoxetine 54910-89-3 99.65%
Fluoxetine
Fluoxetine (LY-110140) is a highly specific serotonin uptake inhibitor and selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine has antidepressant...
T22453 Venlafaxine 93413-69-5 99.62%
Venlafaxine
Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depres...
T11078 Deschloroclozapine 1977-07-7 99.61%
Deschloroclozapine
Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4D...
T8708 Paroxetine 61869-08-7 99.45%
Paroxetine
Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression.
T6188 Desvenlafaxine succinate hydrate 386750-22-7 99.39%
Desvenlafaxine succinate hydrate
Desvenlafaxine succinate hydrate (WY 45233 Succinate) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).
T1483 Citalopram hydrobromide 59729-32-7 99.35%
Citalopram hydrobromide
Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, thereby poten...
T2395 Vortioxetine 508233-74-7 99.34%
Vortioxetine
Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum ...
T7940 Milnacipran ((1S-cis) hydrochloride) 175131-60-9 99.3%
Milnacipran ((1S-cis) hydrochloride)
Milnacipran (1S-cis) hydrochloride (Levomilnacipran Hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI), treatment of fibromyalgia.
T0255 Clomipramine hydrochloride 17321-77-6 99.07%
Clomipramine hydrochloride
Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is ...
TN2285 DL-Tryptophan 54-12-6 98.95%
DL-Tryptophan
DL-Tryptophan ((±)-Tryptophan) containing dipeptides are interesting ingredients for functional foods as a natural prevention for hypertension with reduced side ...
T3526 Dasotraline hydrochloride 675126-08-6 98.92%
Dasotraline hydrochloride
Dasotraline hydrochloride (SEP-225289 hydrochloride) (SEP-225289 hydrochloride) is a triple reuptake inhibitor that inhibits dopamine, norepinephrine, and seroto...
T27047 Clovoxamine fumarate 54739-19-4 98.88%
Clovoxamine fumarate
Clovoxamine fumarate (DU 23811 fumarate) is a 5-hydroxytryptamine reuptake, serotonin and norepinephrine inhibitor with antidepressant and anticonvulsant activit...
T34795 Tedatioxetine 508233-95-2 98.58%
Tedatioxetine
Tedatioxetine (Lu AA24530) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) with antidepressant properties.Tedatioxetine acts as a CYP2D6 substr...
T12232 Nitroxazepine 47439-36-1 98.46%
Nitroxazepine
Nitroxazepine (CIBA 2330Go) is a serotonin-norepinephrine reuptake inhibitor, and treatment depression. Nitroxazepine is a tricyclic antidepressant (TCA) for the...
T24613 PF-00217830 846032-02-8 98.30%
PF-00217830
PF-00217830 is a serotonin 1A receptor agonist, dopamine D2 receptor agonist, and serotonin 2A receptor antagonist.PF-00217830 may be used in the study of schizo...
T1317 Cinchonidine 485-71-2 98.25%
Cinchonidine
Cinchonidine (L-Cinchonidine) is an alkaloid extracted from Cinchona officinalis. It is a pseudo-enantiomer and stereoisomer of cinchonine.
T13458 (Z)-Thiothixene 3313-26-6 97.58%
(Z)-Thiothixene
(Z)-Thiothixene (Thiothixene) is an antagonist of serotonergic receptor.
T7521 Azaphen 24853-80-3 97.12%
Azaphen
Azaphen (Pipofezin hydrochloride) is the reuptake of serotonin inhibitor.with antidepressant action and has sedative effects, suggesting antihistamine activity.
T0185 Escitalopram 128196-01-0 94.62%
Escitalopram
Escitalopram (Seroplex) is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing e...
T1189 Milnacipran hydrochloride 101152-94-7 100%
Milnacipran hydrochloride
Milnacipran hydrochloride (Savella) is a serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders. Milnacipran hydrochloride is a...
Fluoxetine
T0450
Fluoxetine (LY-110140) is a highly specific serotonin uptake inhibitor and selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine has antidepressant...
Venlafaxine
T22453
Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depres...
Deschloroclozapine
T11078
Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4D...
Paroxetine
T8708
Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression.
Desvenlafaxine succinate hydrate
T6188
Desvenlafaxine succinate hydrate (WY 45233 Succinate) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).
Citalopram hydrobromide
T1483
Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, thereby poten...
Vortioxetine
T2395
Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum ...
Milnacipran ((1S-cis) hydrochloride)
T7940
Milnacipran (1S-cis) hydrochloride (Levomilnacipran Hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI), treatment of fibromyalgia.
Clomipramine hydrochloride
T0255
Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is ...
DL-Tryptophan
TN2285
DL-Tryptophan ((±)-Tryptophan) containing dipeptides are interesting ingredients for functional foods as a natural prevention for hypertension with reduced side ...
Dasotraline hydrochloride
T3526
Dasotraline hydrochloride (SEP-225289 hydrochloride) (SEP-225289 hydrochloride) is a triple reuptake inhibitor that inhibits dopamine, norepinephrine, and seroto...
Clovoxamine fumarate
T27047
Clovoxamine fumarate (DU 23811 fumarate) is a 5-hydroxytryptamine reuptake, serotonin and norepinephrine inhibitor with antidepressant and anticonvulsant activit...
Tedatioxetine
T34795
Tedatioxetine (Lu AA24530) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) with antidepressant properties.Tedatioxetine acts as a CYP2D6 substr...
Nitroxazepine
T12232
Nitroxazepine (CIBA 2330Go) is a serotonin-norepinephrine reuptake inhibitor, and treatment depression. Nitroxazepine is a tricyclic antidepressant (TCA) for the...
PF-00217830
T24613
PF-00217830 is a serotonin 1A receptor agonist, dopamine D2 receptor agonist, and serotonin 2A receptor antagonist.PF-00217830 may be used in the study of schizo...
Cinchonidine
T1317
Cinchonidine (L-Cinchonidine) is an alkaloid extracted from Cinchona officinalis. It is a pseudo-enantiomer and stereoisomer of cinchonine.
(Z)-Thiothixene
T13458
(Z)-Thiothixene (Thiothixene) is an antagonist of serotonergic receptor.
Azaphen
T7521
Azaphen (Pipofezin hydrochloride) is the reuptake of serotonin inhibitor.with antidepressant action and has sedative effects, suggesting antihistamine activity.
Escitalopram
T0185
Escitalopram (Seroplex) is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing e...
Milnacipran hydrochloride
T1189
Milnacipran hydrochloride (Savella) is a serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders. Milnacipran hydrochloride is a...
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TargetMol