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SARS-CoV

Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1) is a strain of virus that causes severe acute respiratory syndrome (SARS). It is an enveloped, positive-sense, single-stranded RNA virus which infects the epithelial cells within the lungs. The virus enters the host cell by binding to the ACE2 receptor. It infects humans, bats, and palm civets.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T81205 SARS-CoV-2-IN-66 1807620-38-7 98%
SARS-CoV-2-IN-66
SARS-CoV-2-IN-66 (1), a derivative of vitamin K, functions as an inhibitor of SARS-CoV-2, exhibiting an effective concentration (EC50) of 70.8 μM in VeroE6/TMPRS...
T81206 SARS-CoV-2-IN-65 98%
SARS-CoV-2-IN-65
SARS-CoV-2-IN-65 (compound 2f (81)) is a potent, orally active reversible inhibitor of SARS-CoV-2 entry, primarily obstructing the RBD:ACE2 interaction and TMPRS...
T81207 SARS-CoV-2-IN-64 98%
SARS-CoV-2-IN-64
SARS-CoV-2-IN-64 (compound 9), derived from chenodeoxycholic acid, serves as a potent inhibitor of the SARS-CoV-2 spike glycoprotein [1].
T81208 SARS-CoV-2-IN-63 2350285-21-9 98%
SARS-CoV-2-IN-63
SARS-CoV-2-IN-63 (Compound R3e) serves as an inhibitor of SARS-CoV-2 replication, demonstrating low cytotoxicity. It effectively suppresses viral replication wit...
T81209 SARS-CoV-2-IN-62 2350285-18-4 98%
SARS-CoV-2-IN-62
SARS-CoV-2-IN-62 (Compound R3b) effectively inhibits SARS-CoV-2 replication in Vero E6 and Calu-3 cells, demonstrating low cytotoxicity and EC50 values of 2.97 μ...
T81210 SARS-CoV-2 Mpro-IN-12 370583-15-6 98%
SARS-CoV-2 Mpro-IN-12
SARS-CoV-2 Mpro-IN-12 (compound D026) serves as an inhibitor of the main protease (Mpro) of SARS-CoV-2, exhibiting antiviral properties [1].
T81388 Propiolactone 57-57-8 98%
Propiolactone
Propiolactone (β-propiolactone; 2-Oxetanone), a chemosterilant, effectively inactivates viruses, rendering them non-infectious. It has been utilized at a 1:1000 ...
T81849 MAT-POS-e194df51-1 98%
MAT-POS-e194df51-1
MAT-POS-e194df51-1 is an orally active, non-covalent, non-peptide inhibitor of the SARS-CoV-2 main protease (M^pro) with an IC_50 of 37nM. It exhibits cytotoxici...
T82230 HCoV-OC43-IN-1 2809363-81-1 98%
HCoV-OC43-IN-1
HCoV-OC43-IN-1 (Compound IV-16) serves as an inhibitor of the coronavirus HCoV-OC43, exhibiting antiviral efficacy with an EC50 of 90 nM. It effectively inhibits...
T82257 GRL-1720 TFA 98%
GRL-1720 TFA
GRL-1720 TFA is a potent SARS-CoV-2 Mpro inhibitor, demonstrating anti-SARS-CoV-2 activity with an EC50 of 15 μM [1].
T82622 D1N8 2894770-40-0 98%
D1N8
D1N8 is a potent inhibitor of the SARS-CoV-2 3CL protease, displaying an IC50 value of 0.44 μM and a CC50 value of greater than 20 μM. It holds promise for the d...
T82623 D1N52 2894770-48-8 98%
D1N52
D1N52 is a potent inhibitor of the SARS-CoV-2 3CL protease, demonstrating an inhibitory concentration half-maximal (IC50) value of 0.53 μM [1].
T72364 SARS-CoV-2 3CLpro-IN-5 2913186-57-7 98%
SARS-CoV-2 3CLpro-IN-5
SARS-CoV-2 3CLpro-IN-5 is a covalent inhibitor targeting the 3C-like protease (3CLpro), exhibiting potent inhibitory activity with an IC50 of 3.8 nM and demonstr...
T73051 Leritrelvir 2923310-64-7 98%
Leritrelvir
Leritrelvir (RAY1216) is a potent orally active inhibitor of the SARS-CoV-2 main protease, exhibiting a slow-tight binding mechanism with an inhibition constant ...
T1188 Mizoribine 50924-49-7 99.98%
Mizoribine
Mizoribine (NSC-289637) belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.
T0828 Bromhexine hydrochloride 611-75-6 99.98%
Bromhexine hydrochloride
Bromhexine hydrochloride (Bisolvon) is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.
T0211L Azelastine hydrochloride 79307-93-0 99.94%
Azelastine hydrochloride
Azelastine hydrochloride (Astelin) is a phthalazinone derivative with antihistaminergic activity.
T4474 Asunaprevir 630420-16-5 99.92%
Asunaprevir
Asunaprevir (BMS-650032) is an effective hepatitis C virus (HCV) NS3 protease inhibitor.
T3334 Velpatasvir 1377049-84-7 99.91%
Velpatasvir
Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor. GS-5816 has demonstrated pan-genotypic activity and a h...
T13142L Theodrenaline hydrochloride 2572-61-4 99.89%
Theodrenaline hydrochloride
Theodrenaline hydrochloride is an inhibitor targeting SARS-CoV-2 for the study of hypotension induced by spinal anesthesia.
SARS-CoV-2-IN-66
T81205
SARS-CoV-2-IN-66 (1), a derivative of vitamin K, functions as an inhibitor of SARS-CoV-2, exhibiting an effective concentration (EC50) of 70.8 μM in VeroE6/TMPRS...
SARS-CoV-2-IN-65
T81206
SARS-CoV-2-IN-65 (compound 2f (81)) is a potent, orally active reversible inhibitor of SARS-CoV-2 entry, primarily obstructing the RBD:ACE2 interaction and TMPRS...
SARS-CoV-2-IN-64
T81207
SARS-CoV-2-IN-64 (compound 9), derived from chenodeoxycholic acid, serves as a potent inhibitor of the SARS-CoV-2 spike glycoprotein [1].
SARS-CoV-2-IN-63
T81208
SARS-CoV-2-IN-63 (Compound R3e) serves as an inhibitor of SARS-CoV-2 replication, demonstrating low cytotoxicity. It effectively suppresses viral replication wit...
SARS-CoV-2-IN-62
T81209
SARS-CoV-2-IN-62 (Compound R3b) effectively inhibits SARS-CoV-2 replication in Vero E6 and Calu-3 cells, demonstrating low cytotoxicity and EC50 values of 2.97 μ...
SARS-CoV-2 Mpro-IN-12
T81210
SARS-CoV-2 Mpro-IN-12 (compound D026) serves as an inhibitor of the main protease (Mpro) of SARS-CoV-2, exhibiting antiviral properties [1].
Propiolactone
T81388
Propiolactone (β-propiolactone; 2-Oxetanone), a chemosterilant, effectively inactivates viruses, rendering them non-infectious. It has been utilized at a 1:1000 ...
MAT-POS-e194df51-1
T81849
MAT-POS-e194df51-1 is an orally active, non-covalent, non-peptide inhibitor of the SARS-CoV-2 main protease (M^pro) with an IC_50 of 37nM. It exhibits cytotoxici...
HCoV-OC43-IN-1
T82230
HCoV-OC43-IN-1 (Compound IV-16) serves as an inhibitor of the coronavirus HCoV-OC43, exhibiting antiviral efficacy with an EC50 of 90 nM. It effectively inhibits...
GRL-1720 TFA
T82257
GRL-1720 TFA is a potent SARS-CoV-2 Mpro inhibitor, demonstrating anti-SARS-CoV-2 activity with an EC50 of 15 μM [1].
D1N8
T82622
D1N8 is a potent inhibitor of the SARS-CoV-2 3CL protease, displaying an IC50 value of 0.44 μM and a CC50 value of greater than 20 μM. It holds promise for the d...
D1N52
T82623
D1N52 is a potent inhibitor of the SARS-CoV-2 3CL protease, demonstrating an inhibitory concentration half-maximal (IC50) value of 0.53 μM [1].
SARS-CoV-2 3CLpro-IN-5
T72364
SARS-CoV-2 3CLpro-IN-5 is a covalent inhibitor targeting the 3C-like protease (3CLpro), exhibiting potent inhibitory activity with an IC50 of 3.8 nM and demonstr...
Leritrelvir
T73051
Leritrelvir (RAY1216) is a potent orally active inhibitor of the SARS-CoV-2 main protease, exhibiting a slow-tight binding mechanism with an inhibition constant ...
Mizoribine
T1188
Mizoribine (NSC-289637) belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.
Bromhexine hydrochloride
T0828
Bromhexine hydrochloride (Bisolvon) is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.
Azelastine hydrochloride
T0211L
Azelastine hydrochloride (Astelin) is a phthalazinone derivative with antihistaminergic activity.
Asunaprevir
T4474
Asunaprevir (BMS-650032) is an effective hepatitis C virus (HCV) NS3 protease inhibitor.
Velpatasvir
T3334
Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor. GS-5816 has demonstrated pan-genotypic activity and a h...
Theodrenaline hydrochloride
T13142L
Theodrenaline hydrochloride is an inhibitor targeting SARS-CoV-2 for the study of hypotension induced by spinal anesthesia.
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TargetMol