T81205 |
SARS-CoV-2-IN-66
|
1807620-38-7
|
98%
|
|
SARS-CoV-2-IN-66 (1), a derivative of vitamin K, functions as an inhibitor of SARS-CoV-2, exhibiting an effective concentration (EC50) of 70.8 μM in VeroE6/TMPRS...
|
T81206 |
SARS-CoV-2-IN-65
|
|
98%
|
|
SARS-CoV-2-IN-65 (compound 2f (81)) is a potent, orally active reversible inhibitor of SARS-CoV-2 entry, primarily obstructing the RBD:ACE2 interaction and TMPRS...
|
T81207 |
SARS-CoV-2-IN-64
|
|
98%
|
|
SARS-CoV-2-IN-64 (compound 9), derived from chenodeoxycholic acid, serves as a potent inhibitor of the SARS-CoV-2 spike glycoprotein [1].
|
T81208 |
SARS-CoV-2-IN-63
|
2350285-21-9
|
98%
|
|
SARS-CoV-2-IN-63 (Compound R3e) serves as an inhibitor of SARS-CoV-2 replication, demonstrating low cytotoxicity. It effectively suppresses viral replication wit...
|
T81209 |
SARS-CoV-2-IN-62
|
2350285-18-4
|
98%
|
|
SARS-CoV-2-IN-62 (Compound R3b) effectively inhibits SARS-CoV-2 replication in Vero E6 and Calu-3 cells, demonstrating low cytotoxicity and EC50 values of 2.97 μ...
|
T81210 |
SARS-CoV-2 Mpro-IN-12
|
370583-15-6
|
98%
|
|
SARS-CoV-2 Mpro-IN-12 (compound D026) serves as an inhibitor of the main protease (Mpro) of SARS-CoV-2, exhibiting antiviral properties [1].
|
T81388 |
Propiolactone
|
57-57-8
|
98%
|
|
Propiolactone (β-propiolactone; 2-Oxetanone), a chemosterilant, effectively inactivates viruses, rendering them non-infectious. It has been utilized at a 1:1000 ...
|
T81849 |
MAT-POS-e194df51-1
|
|
98%
|
|
MAT-POS-e194df51-1 is an orally active, non-covalent, non-peptide inhibitor of the SARS-CoV-2 main protease (M^pro) with an IC_50 of 37nM. It exhibits cytotoxici...
|
T82230 |
HCoV-OC43-IN-1
|
2809363-81-1
|
98%
|
|
HCoV-OC43-IN-1 (Compound IV-16) serves as an inhibitor of the coronavirus HCoV-OC43, exhibiting antiviral efficacy with an EC50 of 90 nM. It effectively inhibits...
|
T82257 |
GRL-1720 TFA
|
|
98%
|
|
GRL-1720 TFA is a potent SARS-CoV-2 Mpro inhibitor, demonstrating anti-SARS-CoV-2 activity with an EC50 of 15 μM [1].
|
T82622 |
D1N8
|
2894770-40-0
|
98%
|
|
D1N8 is a potent inhibitor of the SARS-CoV-2 3CL protease, displaying an IC50 value of 0.44 μM and a CC50 value of greater than 20 μM. It holds promise for the d...
|
T82623 |
D1N52
|
2894770-48-8
|
98%
|
|
D1N52 is a potent inhibitor of the SARS-CoV-2 3CL protease, demonstrating an inhibitory concentration half-maximal (IC50) value of 0.53 μM [1].
|
T72364 |
SARS-CoV-2 3CLpro-IN-5
|
2913186-57-7
|
98%
|
|
SARS-CoV-2 3CLpro-IN-5 is a covalent inhibitor targeting the 3C-like protease (3CLpro), exhibiting potent inhibitory activity with an IC50 of 3.8 nM and demonstr...
|
T73051 |
Leritrelvir
|
2923310-64-7
|
98%
|
|
Leritrelvir (RAY1216) is a potent orally active inhibitor of the SARS-CoV-2 main protease, exhibiting a slow-tight binding mechanism with an inhibition constant ...
|
T1188 |
Mizoribine
|
50924-49-7
|
99.98%
|
|
Mizoribine (NSC-289637) belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.
|
T0828 |
Bromhexine hydrochloride
|
611-75-6
|
99.98%
|
|
Bromhexine hydrochloride (Bisolvon) is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.
|
T0211L |
Azelastine hydrochloride
|
79307-93-0
|
99.94%
|
|
Azelastine hydrochloride (Astelin) is a phthalazinone derivative with antihistaminergic activity.
|
T4474 |
Asunaprevir
|
630420-16-5
|
99.92%
|
|
Asunaprevir (BMS-650032) is an effective hepatitis C virus (HCV) NS3 protease inhibitor.
|
T3334 |
Velpatasvir
|
1377049-84-7
|
99.91%
|
|
Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor. GS-5816 has demonstrated pan-genotypic activity and a h...
|
T13142L |
Theodrenaline hydrochloride
|
2572-61-4
|
99.89%
|
|
Theodrenaline hydrochloride is an inhibitor targeting SARS-CoV-2 for the study of hypotension induced by spinal anesthesia.
|