T79228 |
SARS-CoV-2-IN-50
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98%
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SARS-CoV-2-IN-50 (Compound X77C) is a potent inhibitor of the SARS-CoV-2 main protease (M^pro), exhibiting high affinity for the enzyme's catalytic site [1].
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T79234 |
RdRP-IN-7
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98%
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RdRP-IN-7, a RNA-dependent RNA polymerase (RdRp) inhibitor, demonstrates efficacy against SARS-CoV-2 infection with an inhibitory concentration (IC50) of 8.2 μM ...
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T79243 |
SARS-CoV-2-IN-43
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31356-11-3
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98%
|
|
Compound 8h, also known as SARS-CoV-2-IN-43, is a powerful inhibitor effective in obstructing the replication of SARS-CoV-2, exhibiting significant antiviral act...
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T79244 |
SARS-CoV-2-IN-44
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1311271-71-2
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98%
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|
SARS-CoV-2-IN-44, an inhibitor of SARS-CoV-2, effectively suppresses viral replication with an EC50 value of 0.6μM and exhibits negligible cytotoxicity in Calu-3...
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T79245 |
SARS-CoV-2-IN-45
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|
98%
|
|
SARS-CoV-2-IN-45 (Compound 8p) serves as an inhibitor of SARS-CoV-2, effectively hindering viral replication in Calu-3 cells with an EC50 value of 0.5 μM and exh...
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T79278 |
SARS-CoV-2 Mpro-IN-7
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98%
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|
SARS-CoV-2 Mpro-IN-7 (compound 6g) effectively inhibits SARS-CoV-2 main protease (Mpro) with an IC50 value of 8.8 μM and exhibits a cytotoxic concentration (CC50...
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T79279 |
SARS-CoV-2 Mpro-IN-8
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|
98%
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|
SARS-CoV-2 Mpro-IN-8 (compound 6b) is an antiviral agent effective against SARS-CoV-2 [1].
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T79310 |
SARS-CoV-2-IN-53
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|
98%
|
|
ARS-CoV-2-IN-53 (Compd 5d) exhibits an inhibitory effect on SARS-CoV-2 replication, with an effective concentration (EC50) value of 14.3 μM, and demonstrates not...
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T79328 |
SARS-CoV-2-IN-54
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|
98%
|
|
SARS-CoV-2-IN-54 (Compound 2), a SARS-CoV-2 inhibitor, exhibits antiviral activity by impeding the virus in Vero E6 cells with an inhibitory concentration (IC50)...
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T79329 |
SARS-CoV-2-IN-56
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|
98%
|
|
SARS-CoV-2-IN-56 (Compound 63) is a SARS-CoV-2 inhibitor with antiviral activity, demonstrating inhibition of the virus in Vero E6 cells with an IC50 of 0.7 μM [...
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T79339 |
NSC89641
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98%
|
|
NSC89641 demonstrates potent inhibition of MERS-CoV M^pro, achieving an IC_50 value of less than 3.5 µM. Furthermore, it exerts significant inhibitory effects on...
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T79344 |
CDD-1819
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2894104-40-4
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98%
|
|
CDD-1819, a non-covalent and non-peptide compound, serves as a potent SARS-CoV-2 Mpro inhibitor, exhibiting a K i value of 5 nM. It also effectively inhibits the...
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T79345 |
CDD-1733
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2894104-33-5
|
98%
|
|
CDD-1733 is a potent, non-covalent, and non-peptide inhibitor of the SARS-CoV-2 main protease (Mpro) with an inhibition constant (K i) of 12 nM. It effectively i...
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T79346 |
CDD-1845
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2894104-50-6
|
98%
|
|
CDD-1845, a non-covalent, non-peptide inhibitor, exhibits potent inhibition of SARS-CoV-2 M^pro with a K_i value of 3 nM. Additionally, CDD-1845 is effective aga...
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T79376 |
SARS-CoV-2 3CLpro-IN-19
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|
98%
|
|
SARS-CoV-2 3CLpro-IN-19 (Compound C5a), a non-covalent, non-peptide inhibitor of the SARS-CoV-2 3CLpro enzyme, exhibits potent in vitro activity with an IC50 of ...
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T79414 |
SARS-CoV-2-IN-60
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98%
|
|
SARS-CoV-2-IN-60 (compound 5a) is a specific, irreversible inhibitor of SARS-CoV-2 nsp16-nsp10 methyltransferase, competing with S-adenosylmethionine (SAM) and e...
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T79426 |
SARS-CoV-2-IN-61
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|
98%
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|
SARS-CoV-2-IN-61 (compound 8i) is a potent inhibitor of the SARS-CoV-2 PLpro, exhibiting an IC50 of 16 µM and demonstrating antiviral activities [1].
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T79455 |
SARS-CoV-2 Mpro-IN-9
|
2754370-99-3
|
98%
|
|
SARS-CoV-2 Mpro-IN-9 (compound c7), a nonpeptidic, noncovalent inhibitor of SARS-CoV-2 main protease (Mpro), exhibits potent inhibitory action (IC50 = 0.085 μM) ...
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T79462 |
SARS-CoV-2 3CLpro-IN-14
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|
98%
|
|
SARS-CoV-2 3CLpro-IN-14 (compound 11j) is an orally active inhibitor of SARS-CoV-2 3CLpro, demonstrating potent anti-SARS-CoV-2 properties with an EC50 of 0.18 μ...
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T79515 |
SARS-CoV-2 Mpro-IN-10
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|
98%
|
|
SARS-CoV-2 Mpro-IN-10 (27h) is a potent inhibitor of the Mpro enzyme, exhibiting IC50 and EC50 values of 10.9 nM and 43.6 nM, respectively. It is utilized in res...
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