T0242L |
Sitagliptin phosphate monohydrate
|
654671-77-9
|
99.65%
|
|
Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.
|
T15079 |
DBPR108
|
1186426-66-3
|
99.65%
|
|
DBPR108 is an orally bioavailable dipeptide-derived DPP4 inhibitor (IC50: 15 nM) and it has no inhibition on DDP8 and DPP9.
|
T0372 |
Gabexate mesylate
|
56974-61-9
|
99.64%
|
|
Gabexate mesylate (FOY) is a serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and...
|
T7016 |
VR23
|
1624602-30-7
|
99.62%
|
|
VR23 is a potent proteasome inhibitor. Data shows IC50 =1 nM for trypsin-like proteasomes, IC50=50-100 nM for chymotrypsin-like proteasomes, and IC50=3 μM for ca...
|
T8550 |
NDMC101
|
1308631-40-4
|
99.59%
|
|
NDMC101 is an inhibitor of dipeptidyl peptidase-IV activity in human T cells and exhibits immunomodulatory effects. It also acts as a novel inhibitor of NFATc1 a...
|
T13247 |
UK-101
|
1000313-40-5
|
99.58%
|
|
UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting β1i (LMP2), β1c (LMP2), and β5 (LMP2), with IC50s of 104 nM, 15 μM, and 1 μM....
|
T4467 |
UAMC00039 dihydrochloride
|
697797-51-6
|
99.56%
|
|
UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor with an IC50 of 0.48 nM.
|
T3028 |
Tripterin
|
34157-83-0
|
99.48%
|
|
Tripterin (Celastrol) is a natural product, a proteasome inhibitor that inhibits the pancreatic rennet-like activity of the 20S proteasome (IC50=2.5 μM). Tripter...
|
T8978 |
DD1
|
187585-11-1
|
99.46%
|
|
DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.
|
T6027 |
Delanzomib
|
847499-27-8
|
99.46%
|
|
Delanzomib (CEP-18770) is an orally active inhibitor of the chymotrypsin-like activity of proteasome (IC50: 3.8 nM). It only marginally inhibits the tryptic and ...
|
T36583 |
Gly-Pro-pNA hydrochloride
|
103213-34-9
|
99.41%
|
|
Gly-Pro-pNA hydrochloride (Gly-Pro p-nitroanilide hydrochloride) is a dipeptidyl peptidase inhibitor that inhibits dipeptidyl peptidase II, dipeptidyl peptidase ...
|
T0242 |
Sitagliptin
|
486460-32-6
|
99.4%
|
|
Sitagliptin (MK0431), a new oral hypoglycemic (anti-diabetic drug), is a new dipeptidyl peptidase-4 (DPP-4) inhibitor. This enzyme-inhibiting drug is used either...
|
T1176 |
Racecadotril
|
81110-73-8
|
99.39%
|
|
Racecadotril (Acetorphan) has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis.
|
T2370 |
AC-55541
|
916170-19-9
|
99.35%
|
|
AC-55541 (AOB2796) is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobiliz...
|
T9090 |
MUN57694
|
858557-69-4
|
99.24%
|
|
MUN57694 is an inhibitor of 26S proteasome.
|
TQ0038 |
Brensocatib
|
1802148-05-5
|
99.05%
|
|
Brensocatib (AZD7986) is a Dipeptidyl peptidase 1 (DPP1) inhibitor (pIC50s: 6.85, 7.7, 7.6, 7.8, and 7.8 in human, rat, mouse, rabbit, and dog, respectively).
|
T6041 |
Oprozomib
|
935888-69-0
|
99.05%
|
|
Oprozomib (PR-047) (ONX 0912) , an inhibitor for CT-L activity of 20S proteasome β5(IC50=36 nM)/LMP7(IC50=82 nM), is orally bioavailable. Oprozomib also has pote...
|
T2583 |
Cilastatin
|
82009-34-5
|
99.03%
|
|
Cilastatin (MK0791) is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, ...
|
T12710 |
Retagliptin Phosphate
|
1256756-88-3
|
98.97%
|
|
Retagliptin Phosphate (SP 2086) is pharmaceutical composition of DPP-4 inhibitor, for treating type-2 diabetes.
|
T6237 |
Trelagliptin
|
865759-25-7
|
98.94%
|
|
Trelagliptin (SYR-472) is a highly specific and long-acting DPP-4 inhibitor.
|